Results 31 to 40 of about 4,116 (175)

Transcriptome reveals key microRNAs involved in fat deposition between different tail sheep breeds

PLoS ONE, 2022
MicroRNA (miRNA) is a kind of noncoding RNA whose function involved in various biological processes in neuronal maturation and adipocyte cells, such as differentiation, proliferation, development, apoptosis, and metabolism.
Xiaojuan Fei, Meilin Jin, Yuqin Wang, Taotao Li, Zengkui Lu, Zehu Yuan, Huihua Wang, Jian Lu, Kai Quan, Ran Di, Caihong Wei   +10 more
doaj   +2 more sources

Kinetics of the chromosome 14 microRNA cluster ortholog and its potential role during placental development in the pregnant mare [PDF]

, 2018
Background: The human chromosome 14 microRNA cluster (C14MC) is a conserved microRNA (miRNA) cluster across eutherian mammals, reported to play an important role in placental development.
Ball, Barry A, Carossino, Mariano, Daels, Peter, Dini, Pouya, Esteller-Vico, Alejandro, Loux, Shavahn C, Scoggin, Kirsten E   +6 more
core   +7 more sources

Integrated Analysis of lncRNA–miRNA–mRNA Regulatory Network in Rapamycin-Induced Cardioprotection against Ischemia/Reperfusion Injury in Diabetic Rabbits

Cells, 2023
The inhibition of mammalian target of rapamycin (mTOR) with rapamycin (RAPA) provides protection against myocardial ischemia/reperfusion (I/R) injury in diabetes.
Arun Samidurai, Amy L. Olex, Ramzi Ockaili, Donatas Kraskauskas, Sean K. Roh, Rakesh C. Kukreja, Anindita Das   +6 more
doaj   +1 more source

HGG-05. miR-379-5p REGULATES PROLIFERATION, MIGRATION AND INVASION IN BRAF MUTANT-GLIOBLASTOMA [PDF]

Neuro Oncol, 2018
Zhang R, Li K, Ng H.
europepmc   +3 more sources

Circulating Exosomal miRNAs as Novel Biomarkers Perform Superior Diagnostic Efficiency Compared With Plasma miRNAs for Large-Artery Atherosclerosis Stroke

Frontiers in Pharmacology, 2021
Recently, exosomal miRNAs have been reported to be associated with some diseases, and these miRNAs can be used for diagnosis and treatment. However, diagnostic biomarkers of exosomal miRNAs for ischemic stroke have rarely been studied.
Mengying Niu, Hong Li, Xu Li, Xiaoqian Yan, Aijun Ma, Xudong Pan, Xudong Pan, Xiaoyan Zhu   +7 more
doaj   +1 more source

Focal adhesion kinase: Insight into molecular roles and functions in hepatocellular carcinoma [PDF]

, 2017
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide. Due to the high incidence of post-operative recurrence after current treatments, the identification of new and more effective drugs is required.
Alisi, Anna, Crudele, Annalisa, Gnani, Daniela, Panera, Nadia, Romito, Ilaria   +4 more
core   +2 more sources

Gene expression and microrna expression analysis in small arteries of spontaneously hypertensive rats. Evidence for er stress [PDF]

, 2015
Small arteries are known to develop functional and structural alterations in hypertension. However, the mechanisms of this remodeling are not fully understood.We hypothesized that altered gene expression is associated with the development of ...
Arribas, Silvia M., Bakker, Erik N T P, De Vos, Judith, Groma, Gergely, Jongejan, Aldo, Moerland, Perry D., Palao, Teresa, Swärd, Karl, Van Bavel, Ed, Van Weert, Angela   +9 more
core   +5 more sources

miRNA-mRNA integrative analysis in primary myelofibrosis CD34+ cells: role of miR-155/JARID2 axis in abnormal megakaryopoiesis [PDF]

, 2014
Primary myelofibrosis (PMF) is a myeloproliferative neoplasm characterized by megakaryocyte (MK) hyperplasia, bone marrow fibrosis, and abnormal stem cell trafficking. PMF may be associated with somatic mutations in JAK2, MPL, or CALR.
Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative, Investigators, Barosi, Giovanni, Bianchi, Elisa, Bisognin, Andrea, Bogani, Costanza, Bortoluzzi, Stefania, Cazzola, Mario, Fanelli, Tiziana, Ferrari, Sergio, Guglielmelli, Paola, Manfredini, Rossella, Mannarelli, Carmela, Norfo, Ruggiero, Pennucci, Valentina, Pietra, Daniela, Prudente, Zelia, Rambaldi, Alessandro, Rontauroli, Sebastiano, Rosti, Vittorio, Ruberti, Samantha, Sacchi, Giorgia, Salati, Simona, Salmoiraghi, Silvia, Tagliafico, Enrico, Vannucchi, Alessandro M, Zini, Roberta   +25 more
core   +1 more source

A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons [PDF]

, 2018
Mutations in fused in sarcoma (FUS) cause amyotrophic lateral sclerosis (ALS). FUS is a multifunctional protein involved in the biogenesis and activity of several types of RNAs, and its role in the pathogenesis of ALS may involve both direct effects of
Biscarini, Silvia, Bozzoni, Irene, Caffarelli, Elisa, Capauto, Davide, Colantoni, Alessio, Laneve, Pietro, Lu, Lei, Morlando, Mariangela, Peruzzi, Giovanna, Santini, Tiziana, Shneider, Neil A.   +10 more
core   +2 more sources

miR-379 links glucocorticoid treatment with mitochondrial response in Duchenne muscular dystrophy [PDF]

, 2020
Duchenne Muscular Dystrophy (DMD) is a lethal muscle disorder, caused by mutations in the DMD gene and affects approximately 1:5000-6000 male births. In this report, we identified dysregulation of members of the Dlk1-Dio3 miRNA cluster in muscle biopsies
Amor, F, Barthélémy, I, Bigot, A, Blot, S, Bourg, N, Bénit, P, Corre, G, Israeli, D, Massourides, E, Pinset, C, Richard, I, Rustin, P, Sanson, M, Servais, L, Suel, L, Voit, T, Vu Hong, A   +16 more
core   +4 more sources