Cells, 2023 The inhibition of mammalian target of rapamycin (mTOR) with rapamycin (RAPA) provides protection against myocardial ischemia/reperfusion (I/R) injury in diabetes.
Arun Samidurai +6 more
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HGG-05. miR-379-5p REGULATES PROLIFERATION, MIGRATION AND INVASION IN BRAF MUTANT-GLIOBLASTOMA [PDF]
Neuro Oncol, 2018 Zhang R, Li K, Ng H.
europepmc +3 more sources
Frontiers in Pharmacology, 2021 Recently, exosomal miRNAs have been reported to be associated with some diseases, and these miRNAs can be used for diagnosis and treatment. However, diagnostic biomarkers of exosomal miRNAs for ischemic stroke have rarely been studied.
Mengying Niu +7 more
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Altered microRNA profile during fracture healing in rats with diabetes
Journal of Orthopaedic Surgery and Research, 2020 Background MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that regulate gene expression. There is increasing evidence that some miRNAs are involved in the pathology of diabetes mellitus (DM) and its complications.
Shunsuke Takahara +11 more
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Pro-fibrotic and apoptotic activities of circARAP1 in myocardial ischemia–reperfusion injury
European Journal of Medical Research, 2023 Reperfusion modality can cause damage to cardiomyocytes, known as myocardial ischemia–reperfusion injury (MI/RI). Circular RNAs (circRNAs) are fundamental regulators associated with many cardiac diseases, including MI/RI. However, their functional impact
Xi Li, Lei Guo, Jingjing Wang, Xing Yang
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Evaluating the expression of miRNAs in the culture medium of human embryos with normal sex chromosomes and embryos with an X sex chromosome (Turner syndrome) [PDF]
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023 Introduction: Assisted reproductive techniques and Preimplantation Genetic Test (PGT) are performed to detect aneuploidy to achieve a euploid baby's birth in infertile or low-fertility couples.
Shahrzad Aghajani +3 more
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microRNAs profiling of small extracellular vesicles from midbrain tissue of Parkinson’s disease
Frontiers in Molecular Neuroscience, 2023 Small extracellular vesicles (sEVs) are generated by all types of cells during physiological or pathological conditions. There is growing interest in tissue-derived small extracellular vesicles (tdsEVs) because they can be isolated from a single tissue ...
Zhengzhe Li +12 more
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mir-374-5p, mir-379-5p, and mir-503-5p Regulate Proliferation and Hypertrophic Differentiation of Growth Plate Chondrocytes in Male Rats. [PDF]
Endocrinology, 2018 Growth plate chondrocytes undergo sequential differentiation to form the resting zone, the proliferative zone (PZ), and the hypertrophic zone (HZ). The important role of microRNAs (miRNAs) in the growth plate was previously revealed by cartilage-specific ablation of Dicer, an enzyme essential for biogenesis of many miRNAs.
Jee YH +7 more
europepmc +4 more sources
Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome
Frontiers in Cell and Developmental Biology, 2021 Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno +3 more
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Cells, 2021 Infants with congenital diaphragmatic hernia (CDH) are at high risk of postnatal mortality due to lung hypoplasia and arterial pulmonary hypertension.
Isabella Fabietti +10 more
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