Results 31 to 40 of about 248,159 (173)

A Concise Review on Dysregulation of LINC00665 in Cancers

open access: yesCells, 2022
Long Intergenic Non-Protein Coding RNA 665 (LINC00665) is an RNA gene located on the minus strand of chromosome 19. This lncRNA acts as a competing endogenous RNA for miR-4458, miR-379-5p, miR-551b-5p, miR-3619-5p, miR-424-5p, miR-9-5p, miR-214-3p, miR ...
Soudeh Ghafouri-Fard   +5 more
doaj   +1 more source

AKR1C3 decreased CML sensitivity to Imatinib in bone marrow microenvironment via dysregulation of miR-379-5p

open access: yesCellular Signalling, 2021
Drug resistance is an important cause of death for most patients with chronic myeloid leukemia (CML). The bone marrow microenvironment is believed to be mainly responsible for resistance to BCR-ABL tyrosine kinase inhibitors. The mechanism involved, however, is still unclear.Bioinformatic analysis from GEO database of AKR1C3 was utilized to identify ...
Di, Pan   +8 more
openaire   +2 more sources

SNHG1-miR-186-5p-YY1 feedback loop alleviates hepatic ischemia/reperfusion injury [PDF]

open access: yes, 2022
As a common cause of liver injury, hepatic ischemia/reperfusion injury (HIRI) happens in various clinical conditions including trauma, hepatectomy and liver transplantation.
Qiang Sun (225630)   +5 more
core   +1 more source

Transcriptome reveals key microRNAs involved in fat deposition between different tail sheep breeds

open access: yesPLoS ONE, 2022
MicroRNA (miRNA) is a kind of noncoding RNA whose function involved in various biological processes in neuronal maturation and adipocyte cells, such as differentiation, proliferation, development, apoptosis, and metabolism.
Xiaojuan Fei   +10 more
doaj   +2 more sources

Integrated Analysis of lncRNA–miRNA–mRNA Regulatory Network in Rapamycin-Induced Cardioprotection against Ischemia/Reperfusion Injury in Diabetic Rabbits

open access: yesCells, 2023
The inhibition of mammalian target of rapamycin (mTOR) with rapamycin (RAPA) provides protection against myocardial ischemia/reperfusion (I/R) injury in diabetes.
Arun Samidurai   +6 more
doaj   +1 more source

MiR-942-5p regulates the expression of CST1. [PDF]

open access: yes, 2023
(A) Conserved binding sites of four miRNAs to CST1 sequences. (B) Expression of miR-942-5p in 7 cell lines. (C) Expression of miR-942-5p after transfection of mimics. (D) Expression of miR-942-5p after transfection of inhibitor.
Yi Zhang (9093)   +9 more
core   +1 more source

Circulating Exosomal miRNAs as Novel Biomarkers Perform Superior Diagnostic Efficiency Compared With Plasma miRNAs for Large-Artery Atherosclerosis Stroke

open access: yesFrontiers in Pharmacology, 2021
Recently, exosomal miRNAs have been reported to be associated with some diseases, and these miRNAs can be used for diagnosis and treatment. However, diagnostic biomarkers of exosomal miRNAs for ischemic stroke have rarely been studied.
Mengying Niu   +7 more
doaj   +1 more source

Potential Predictive Value of miR-125b-5p, miR-155-5p and Their Target Genes in the Course of COVID-19 [PDF]

open access: yes, 2022
Xuewen Li,1 Yiting Wang,1 Qi Zhou,2 Junqi Pan,3 Jiancheng Xu1 1Department of Laboratory Medicine, First Hospital of Jilin University, Changchun, People’s Republic of China; 2Department of Pediatrics, First Hospital of Jilin University, Changchun, People ...
Li X, Pan J, Zhou Q, Wang Y, Xu J
core  

Analysis of the Inhibitory Effect of hsa-miR-145-5p and hsa-miR-203a-5p on Imatinib-Resistant K562 Cells by GC/MS Metabolomics Method [PDF]

open access: yes, 2023
Imatinib (IM) resistance is considered to be a significant challenge in the management of chronic myeloid leukemia (CML). Previous studies have reported that hsa-miR-145-5p and hsa-miR-203a-5p can overcome IM resistance and hsa-miR-203a-5p can alter ...
Priyanka Singh (256412)   +7 more
core   +1 more source

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