Results 51 to 60 of about 319,465 (163)

Establishment of Repertoire of Placentome-Associated MicroRNAs and Their Appearance in Blood Plasma Could Identify Early Establishment of Pregnancy in Buffalo (Bubalus bubalis)

open access: yesFrontiers in Cell and Developmental Biology, 2021
Precise early pregnancy diagnosis in dairy animals is of utmost importance for an efficient dairy production system. Not detecting a dairy animal pregnant sufficiently early after the breeding results to extending the unproductive time of their milk ...
Parul Sarwalia   +14 more
doaj   +1 more source

Bioinformatics predicted oar-miR-3955-5p binding sites on XLOC005698, and oar-miR-544-5p binding sites on XLOC000629.

open access: yes, 2016
(a) Alignment between XLOC005698 and oar-miR-3955-5p as well as between XLOC000629 and oar-miR-544-5p. (b) The oar-miR-3955-5p miRNA binding sites on XLOC005698. (c)The oar-miR-544-5p miRNA binding sites on XLOC000629.
Tingting Guo (101831)   +8 more
core   +1 more source

miR-149-5p mitigates tumor necrosis factor-α-induced chondrocyte apoptosis by inhibiting TRADD

open access: yes, 2020
Introduction Chondrocyte apoptosis as a prominent characteristic is usually accompanied by cartilage degeneration in osteoarthritis (OA). Herein, we aimed to determine the roles of miR-149-5p in tumor necrosis factor-α (TNF-α)-induced chondrocyte ...
Shi-cheng Xie   +4 more
core   +1 more source

Additional file 1 of Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: cellular mechanism involved in polycystic ovaries

open access: yes, 2023
Additional file 1: Supplementary Figure 1. Androgen excess in human PCOS subjects is associated with reduced follicular fluid-derived exosomal mir-379-5p content and granulosa cell proliferation. (A) Follicular fluids from the dominant follicles (≥ 20 mm;
Reza Salehi (8272320)   +19 more
core   +1 more source

Understanding of Molecular Mechanisms and Breeding Strategies for Enhancing Oleic Acid Biosynthesis in Oil Crops

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Oleic acid (C18:1), a monounsaturated fatty acid, is a key determinant of nutritional value and oxidative stability of vegetable oils. Increasing its concentration has therefore become a central objective in oilseed crop improvement. This review summarizes current knowledge on the molecular mechanisms and breeding strategies underlying oleic ...
Muhammad Jawad Umer   +12 more
wiley   +1 more source

MicroRNA-379-5p attenuates cancer stem cells and reduces cisplatin resistance in ovarian cancer by regulating RAD18/Polη axis

open access: yesCell Death and Disease
Ovarian cancer (OC) is an aggressive malignancy of the female reproductive organs, associated with a low 5-year survival rate. Emerging evidence suggests the pivotal role of microRNAs (miRNAs) in regulating chemoresistance and metastasis in OC, primarily
Devendra Shukla   +10 more
doaj   +1 more source

MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background RNA binding proteins (RBPs) have been reported to interact with RNAs to regulate gene expression. Circular RNAs (circRNAs) are a type of endogenous non-coding RNAs, which involved in the angiogenesis of tumor.
Qianru He   +9 more
doaj   +1 more source

Small RNA Sequencing Uncovers New miRNAs and moRNAs Differentially Expressed in Normal and Primary Myelofibrosis CD34+ Cells. [PDF]

open access: yesPLoS ONE, 2015
Myeloproliferative neoplasms (MPN) are chronic myeloid cancers thought to arise at the level of CD34+ hematopoietic stem/progenitor cells. They include essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF).
Paola Guglielmelli   +6 more
doaj   +1 more source

miR-218-5p directly targets HMGB2 and CMPK1 3'UTR.

open access: yes, 2019
(A). Luciferase activity in HEK293T cells cotransfected with miR-218-5p mimic (miR-218-5p; 10 nM) or its control (NC of mimic; 10 nM) and the reporter constructs for 48 h. (B). Luciferase activity in HEK293T cells cotransfected with increasing amounts of
Qin Yan (281622)   +6 more
core   +1 more source

Osteoarthritis: Epidemiology, Diagnosis, and Treatment

open access: yesMedComm, Volume 7, Issue 7, July 2026.
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru   +7 more
wiley   +1 more source

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