Results 51 to 60 of about 248,159 (173)

Extracellular Vesicles and Their miRNA Content in Amniotic and Tracheal Fluids of Fetuses with Severe Congenital Diaphragmatic Hernia Undergoing Fetal Intervention

open access: yesCells, 2021
Infants with congenital diaphragmatic hernia (CDH) are at high risk of postnatal mortality due to lung hypoplasia and arterial pulmonary hypertension.
Isabella Fabietti   +10 more
doaj   +1 more source

Identification of miRNA biomarkers for stomach adenocarcinoma

open access: yesBMC Bioinformatics, 2022
Background Stomach adenocarcinoma (STAD) is a common malignant tumor in the world and its prognosis is poor, miRNA plays a role mainly by influencing the expression of mRNAs, and participates in the occurrence and development of tumors. However, reliable
Hao Qian   +3 more
doaj   +1 more source

MicroRNA Signatures in Cartilage Ageing and Osteoarthritis

open access: yesBiomedicines, 2023
Osteoarthritis is the most common degenerative joint disorder. MicroRNAs are gene expression regulators that act post-transcriptionally to control tissue homeostasis.
Panagiotis Balaskas   +7 more
doaj   +1 more source

MiR-21-5p, miR-18a-5p, miR-27a-3p and miR-423-5p expression in AMI_T0 and CAD groups (n = 3). [PDF]

open access: yes, 2019
(A) MiR-21-5p expression in CAD and AMI_T0 groups. Mann-Whitney U = 196, n.s. (B) MiR-18a-5p expression in CAD and AMI_T0 groups. Mann-Whitney U = 190, n.s. (C) MiR-27a-3p expression in CAD and AMI_T0 groups. Mann-Whitney U = 106, n.s.
Ruggiero Mango (266696)   +11 more
core   +1 more source

BCL11A expression was negatively regulated by hsa-miR-190b-5p. [PDF]

open access: yes, 2023
(A, B) qRT-PCR and Western blot analysis of the mRNA and protein expression levels of BCL11A in 293T cells after transfected hsa-miR-190b-5p mimics and negative control mimics. β-actin gene was used as the internal control. (C) hsa-miR-190b-5p expression
Hailong Huang (1449589)   +9 more
core   +1 more source

Data_Sheet_1_CAGE-miR-140-5p-Wnt1 Axis Regulates Autophagic Flux, Tumorigenic Potential of Mouse Colon Cancer Cells and Cellular Interactions Mediated by Exosomes.pdf [PDF]

open access: yes, 2019
Although the cancer/testis antigen CAGE has been implicated in tumorigenesis, the molecular mechanisms of CAGE-promoted tumorigenesis remain largely unknown.
Seungheon Lee (7862393)   +5 more
core   +1 more source

The E‐cadherin‐Wnt‐mir‐994 Axis Repurposes a Cadherin Switch for Niche Robustness and Germline Stem Cell Maintenance

open access: yesCell Proliferation, EarlyView.
In the Drosophila ovarian niche, an E‐cadherin‐to‐N‐cadherin switch, mediated by Wnt‐mir‐994 signalling, is repurposed to ensure niche resilience. This compensatory mechanism maintains niche integrity and stem cell support upon E‐cadherin loss, revealing a robustness circuit.
Renjun Tu   +6 more
wiley   +1 more source

Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: The cellular mechanism of anovulatory polycystic ovaries

open access: yes, 2023
Abstract Polycystic ovarian syndrome (PCOS) is a complex multi-factorial syndrome associated with androgen excess and anovulatory infertility. In the current study, we investigated the role of dihydrotestosterone-induced exosomal miR-379-5p release in determining the destiny of the developing follicles.
Reza Salehi   +19 more
openaire   +1 more source

MiR-497-5p, miR-195-5p and miR-455-3p function as tumor suppressors by targeting hTERT in melanoma A375 cells [PDF]

open access: yes, 2018
Li Chai,1 Xiao-Jing Kang,2 Zhen-Zhu Sun,3 Ming-Feng Zeng,2 Shi-Rong Yu,2 Yuan Ding,2 Jun-Qin Liang,2 Ting-Ting Li,2 Juan Zhao2 1Xinjiang Medical University, Urumqi, China; 2Department of Dermatology and Venereology, People’s Hospital of Xinjiang ...
Sun ZZ   +8 more
core  

Exosomal miRNA-223-3p derived from tumor associated macrophages promotes pulmonary metastasis of breast cancer 4T1 cells

open access: yesTranslational Oncology, 2023
Research about the effect of exosomes derived from tumor associated macrophages (TAM-exos) in the distant organ metastasis of breast cancer is limited. In this study, we found that TAM-exos could promote the migration of 4T1 cells.
Ziyuan Wang   +7 more
doaj   +1 more source

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