Results 61 to 70 of about 248,159 (173)
ABSTRACT Oleic acid (C18:1), a monounsaturated fatty acid, is a key determinant of nutritional value and oxidative stability of vegetable oils. Increasing its concentration has therefore become a central objective in oilseed crop improvement. This review summarizes current knowledge on the molecular mechanisms and breeding strategies underlying oleic ...
Muhammad Jawad Umer +12 more
wiley +1 more source
miR-30b-5p inhibits osteoblast differentiation through targeting BCL6 [PDF]
Human bone marrow mesenchymal stem cells (hBMSCs) are attractive candidates for new therapies to improve bone regeneration and repair. This study was to identify the function of the miR-30b-5p/BCL6 axis in osteogenic differentiation of hBMSCs.
Bin Ye (686390) +4 more
core +1 more source
Fei Zhang,1 Chuanxin Duan,1 Shucheng Yin,2 Ying Tian1 1Department of Otolaryngology, Maternal and Child Health Care Hospital of Hubei Province and Women and Children’s Hospital of Hubei Province, Wuhan 430070, People’s Republic of China ...
Zhang F, Duan C, Yin S, Tian Y
doaj
Osteoarthritis: Epidemiology, Diagnosis, and Treatment
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru +7 more
wiley +1 more source
EBV-miR-BART1-5P enhances glycolysis of NPC cells. [PDF]
(A) Lactate production, glucose consumption and 2-NBDG uptake (Magnification, ×100) in HONE and CNE1 cells after transfection EBV-miR-BART1-5P mimic alone or co-transfection EBV-miR-BART1-5P mimic and PTEN plasmid.
Jianguo Wang (1400488) +17 more
core +1 more source
BCL11A was a target of hsa-miR-190b-5p. [PDF]
(A) The human BCL11A mRNA 3’-UTR harbored two putative binding sites (499–506 loci: ACATATC; 2553–2559 loci: ACATATC) of hsa-miR-190b-5p. These mutant binding sites (ACATATC>TGTATAG) were shown below. (B) qRT-PCR analysis of hsa-miR-190b-5p expression in
Hailong Huang (1449589) +9 more
core +1 more source
miR-483-5p and incident diabetes. [PDF]
miR-483-5p and incident diabetes.
Widet Gallo (4533472) +3 more
core +1 more source
Diagnostic and prognostic potential of eight whole blood microRNAs for equine sarcoid disease.
MicroRNAs have been proposed as biomarkers for equine sarcoids, the most prevalent equine skin tumors globally. This study served to validate the diagnostic and prognostic potential of whole blood microRNAs identified in a previous study for long-term ...
Jeanne Cosandey +7 more
doaj +1 more source
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li +5 more
wiley +1 more source
miR-708-5p inhibited STK4-mediated Hippo-YAP1 signaling pathway. [PDF]
(A) The targeting sequence of miR-708-5p in the 3’UTR of STK4 was predicated using Starbase (http://starbase.sysu.edu.cn/index.php). (B) The interaction between miR-708-5p and STK4 was identified using dual-luciferase reporter assay.
Hongyu Liang (201342) +3 more
core +1 more source

