Results 61 to 70 of about 4,116 (175)
Salivary miR-21 is a potential biomarker for canine mast cell tumors [PDF]
, 2022 MicroRNAs (miRNAs) are a class of noncoding RNA molecules playing a crucial role in tumor modulation targeting mRNA. This study aimed to validate the diagnostic potential of a panel of 3 miRNAs previously identified in canine mast cell tumors (MCTs), miR-
Cristina Lecchi +7 more
core +1 more source
Molecular characterization of the A52 murine hepatocellular carcinoma cell line
Animal Models and Experimental Medicine, EarlyView.Hepatocellular carcinoma (HCC) is a poor outcome cancer with limited therapeutic choices. To advance therapeutic development we genetically characterized the A52 murine HCC cell line. We noted genetic changes that match a subset of human HCC and this offers the opportunity to test novel targeted therapies in syngeneic mice.
Rhys Gillman +5 more
wiley +1 more source
Cancer Management and Research, 2020 Fei Zhang,1 Chuanxin Duan,1 Shucheng Yin,2 Ying Tian1 1Department of Otolaryngology, Maternal and Child Health Care Hospital of Hubei Province and Women and Children’s Hospital of Hubei Province, Wuhan 430070, People’s Republic of China ...
Zhang F, Duan C, Yin S, Tian Y
doaj
Research progress on biomarkers of traumatic brain injury
Animal Models and Experimental Medicine, EarlyView.Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen +8 more
wiley +1 more source
, 2023 Abstract Polycystic ovarian syndrome (PCOS) is a complex multi-factorial syndrome associated with androgen excess and anovulatory infertility. In the current study, we investigated the role of dihydrotestosterone-induced exosomal miR-379-5p release in determining the destiny of the developing follicles.
Reza Salehi +19 more
openaire +1 more source
Diagnostic and prognostic potential of eight whole blood microRNAs for equine sarcoid disease.
PLoS ONE, 2021 MicroRNAs have been proposed as biomarkers for equine sarcoids, the most prevalent equine skin tumors globally. This study served to validate the diagnostic and prognostic potential of whole blood microRNAs identified in a previous study for long-term ...
Jeanne Cosandey +7 more
doaj +1 more source
Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, EarlyView.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Aging‐Driven Immunosuppression: The Role of Tregs in the Ovarian Tumor Microenvironment
Aging Cell, Volume 25, Issue 5, May 2026.In the aged ovarian TME, cancer cells exhibit increased succinate production. Elevated extracellular succinate activates the SUCNR1 receptor on Tregs, promoting their recruitment and contributing to an immunosuppressive environment. This leads to diminished anti‐tumor T cell responses and reduced survival.
Mary P. Udumula +10 more
wiley +1 more source
Redox Biology, 2018 Methyltransferase DNMT2 is suggested to be involved in the regulation of numerous processes, however its biological significance and underlying molecular mechanisms remain elusive.
Anna Lewinska +6 more
doaj +1 more source
Combining laser microdissection and microRNA expression profiling to unmask microRNA signatures in complex tissues [PDF]
, 2019 Neglecting tissue heterogeneity during the analysis of microRNA (miRNA) levels results in average signals from an unknown mixture of different cell types that are difficult to interpret.
Hackl, Matthias +5 more
core +1 more source