Results 21 to 30 of about 248,159 (173)
Linchuang shenzangbing zazhi, 2022 ObjectiveTo explore the effect of chikusetsu saponin Ⅳa （CHS） on high glucose-induced human renal tubular epithelial cells （HK-2） injury and examine whether or not its mechanism is correlated with the regulation of circEIF4G2 and miR-379-5p expression ...
Qin Li +3 more
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LINC00665 promotes breast cancer progression through regulation of the miR-379-5p/LIN28B axis. [PDF]
Cell Death Dis, 2020 AbstractBreast cancer is the most common malignant tumor among women worldwide. Although increasing evidence indicates that long noncoding RNAs (lncRNAs) play critical roles during breast tumorigenesis and progression, the involvement of most lncRNAs in breast cancer remains largely unknown. In the current study, we demonstrated that LINC00665 promotes
Ji W +5 more
europepmc +4 more sources
miR-379-5P INHIBITION ENHANCES INTESTINAL EPITHELIAL PROLIFERATION AND BARRIER FUNCTION RECOVERY AFTER ISCHEMIA/REPERFUSION BY TARGETING EIF4G2. [PDF]
Shock, 2023 ABSTRACT Gut barrier dysfunction caused by intestinal ischemia/reperfusion (I/R) injury is associated with substantial death and morbidity. In this research, the role of microRNAs (miRNAs) in regulating intestinal I/R injury was investigated. We used miRNA sequencing to analyze clinical ischemic and normal intestinal samples.
Jia Z +5 more
europepmc +3 more sources
Endogenous and Extracellular Roles of a Tumor Suppressor miR-379-5p in Gastric Cancer.
Oncology<p>Introduction: MiRNAs play important roles in development of various cancers including gastric cancer. Exosomes are extracellular vesicles for translocating molecules. This study aimed to investigate the tumor suppressive roles of miR-379-5p in gastric cancer and to investigate the roles of exosomes in transporting miR-379-5p from intracellular
Liu MX, Chu KM.
europepmc +3 more sources
miR‑379‑5p inhibits cell proliferation and promotes cell apoptosis in non‑small cell lung cancer by targeting β‑arrestin‑1. [PDF]
Mol Med Rep, 2020 Lung cancer is the most common fatal type of cancer, demonstrating high incidence rates in both sexes. Therefore, it is of vital importance to devise more effective and targeted therapies to improve the treatment quality for patients. The present study aimed to determine the effects of microRNA (miR)‑379‑5p on cell proliferation and apoptosis, in ...
Jiang Y, Zhu P, Gao Y, Wang A.
europepmc +4 more sources
Author Correction: hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p. [PDF]
Sci RepHuang S +5 more
europepmc +3 more sources
Acta Biochimica Polonica, 2021 Endometrial cancer is a common gynecological malignancy, and the incidence of this disease has increased in recent years. Recently, some studies suggested that the expression of miR-379-5p suppressed the metastasis of breast cancer cells. However, whether the expression of miR-379-5p could affect the proliferation, migration and invasion of endometrial
Minglin, Liang, Hui, Chen, Jie, Min
openaire +3 more sources
The Effect of miR-34a-5p and miR-145-5p Ectopic Expression on Cell Proliferation and Target Gene Expression in the MDA-MB-231 Cell Line [PDF]
, 2021 Aim:It was aimed to investigate the effect of miR-34a-5p and miR-145-5p on breast cancer cell line MDA-MB-231 and to determine the expression of target genes of these microRNAs (miRNAs).Materials and Methods:Firstly, literature search and in silico ...
Emre ÖZGÜR +5 more
core +1 more source
Kaohsiung Journal of Medical Sciences, 2022 MicroRNAs (miRNAs) are abundant in neurons and play key roles in the function and development of the nervous system. This study focuses on the function of miR‐379‐5p in neurological function recovery during ischemic stroke.
Yun Mo +4 more
doaj +1 more source
Molecular Biomedicine, 2022 Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driving factors in the transition from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).
Yunxia Dong +8 more
doaj +1 more source