Results 21 to 30 of about 4,048 (141)
LINC00665/miR-379-5p/GRP78 regulates cisplatin sensitivity in gastric cancer by modulating endoplasmic reticulum stress. [PDF]
Cytotechnology, 2021 Acquired resistance to cisplatin (DDP)-based chemotherapy greatly hinders the treatment of gastric cancer (GC). LINC00665 serves as an oncogene in GC. Hence, the current study was designed to investigate the regulatory effects of LINC00665 on DDP-resistance of GC.
Yue C, Yu C, Peng R, Wang J, Li G, Xu L.
europepmc +3 more sources
Endogenous and Extracellular Roles of a Tumor Suppressor miR-379-5p in Gastric Cancer.
Oncology<p>Introduction: MiRNAs play important roles in development of various cancers including gastric cancer. Exosomes are extracellular vesicles for translocating molecules. This study aimed to investigate the tumor suppressive roles of miR-379-5p in gastric cancer and to investigate the roles of exosomes in transporting miR-379-5p from intracellular
Liu MX, Chu KM.
europepmc +3 more sources
miR‑379‑5p inhibits cell proliferation and promotes cell apoptosis in non‑small cell lung cancer by targeting β‑arrestin‑1. [PDF]
Mol Med Rep, 2020 Lung cancer is the most common fatal type of cancer, demonstrating high incidence rates in both sexes. Therefore, it is of vital importance to devise more effective and targeted therapies to improve the treatment quality for patients. The present study aimed to determine the effects of microRNA (miR)‑379‑5p on cell proliferation and apoptosis, in ...
Jiang Y, Zhu P, Gao Y, Wang A.
europepmc +4 more sources
Author Correction: hsa_circ_0008305 facilitates the malignant progression of hepatocellular carcinoma by regulating AKR1C3 expression and sponging miR-379-5p. [PDF]
Sci RepHuang S +5 more
europepmc +3 more sources
Acta Biochimica Polonica, 2021 Endometrial cancer is a common gynecological malignancy, and the incidence of this disease has increased in recent years. Recently, some studies suggested that the expression of miR-379-5p suppressed the metastasis of breast cancer cells. However, whether the expression of miR-379-5p could affect the proliferation, migration and invasion of endometrial
Minglin, Liang, Hui, Chen, Jie, Min
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Kaohsiung Journal of Medical Sciences, 2022 MicroRNAs (miRNAs) are abundant in neurons and play key roles in the function and development of the nervous system. This study focuses on the function of miR‐379‐5p in neurological function recovery during ischemic stroke.
Yun Mo +4 more
doaj +1 more source
Molecular Biomedicine, 2022 Lipotoxicity induced by the overload of lipid in the liver, especially excess free cholesterol (FC), has been recognized as one of driving factors in the transition from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH).
Yunxia Dong +8 more
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A Concise Review on Dysregulation of LINC00665 in Cancers
Cells, 2022 Long Intergenic Non-Protein Coding RNA 665 (LINC00665) is an RNA gene located on the minus strand of chromosome 19. This lncRNA acts as a competing endogenous RNA for miR-4458, miR-379-5p, miR-551b-5p, miR-3619-5p, miR-424-5p, miR-9-5p, miR-214-3p, miR ...
Soudeh Ghafouri-Fard +5 more
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Cellular Signalling, 2021 Drug resistance is an important cause of death for most patients with chronic myeloid leukemia (CML). The bone marrow microenvironment is believed to be mainly responsible for resistance to BCR-ABL tyrosine kinase inhibitors. The mechanism involved, however, is still unclear.Bioinformatic analysis from GEO database of AKR1C3 was utilized to identify ...
Di, Pan +8 more
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Transcriptome reveals key microRNAs involved in fat deposition between different tail sheep breeds
PLoS ONE, 2022 MicroRNA (miRNA) is a kind of noncoding RNA whose function involved in various biological processes in neuronal maturation and adipocyte cells, such as differentiation, proliferation, development, apoptosis, and metabolism.
Xiaojuan Fei +10 more
doaj +2 more sources