Stroke: Epidemiology, Risk Factors, Signaling Pathways, and Clinical Management
Overview of clinical management strategies for acute and rehabilitative phases of stroke. The clinical management of IS involves reperfusion therapy during the acute phase and general supportive therapy, including blood pressure management, glucose management, antiplatelet therapy, and rehabilitation therapy during the recovery phase. Stem cell therapy
He Ren +6 more
wiley +1 more source
This review systematically outlines recent advances in the catalytic strategies for converting CO₂ into valuable products, including photocatalysis, electrocatalysis, CO2 hydrogenation, photothermal catalysis, non‐thermal plasma, and biocatalytic processes.
An Zhang +68 more
wiley +1 more source
Fenchone, thiofenchone, and selenofenchone (chalcogenofenchones) are characterized using gas‐phase spectroscopic experiments. The experimentally determined energies of excited states are supported by quantum chemical calculations. Furthermore, near‐ultraviolet femtosecond laser pulses are used to measure the state‐resolved photoelectron circular ...
Sudheendran Vasudevan +23 more
wiley +1 more source
Expression analysis of lung miRNAs responding to ovine VM virus infection by RNA-seq [PDF]
Background: MicroRNAs (miRNAs) are short endogenous, single-stranded, noncoding small RNA molecules of approximately 22 nucleotides in length. They regulate gene expression posttranscriptionally by silencing mRNA expression, thus orchestrating many ...
Abendaño, Naiara +5 more
core +1 more source
The metastatic potential of seminomatous germ cell tumours is associated with a specific microRNA pattern [PDF]
Background Seminomatous germ cell tumours (SGCT) are the most frequent malignancy in young men. Reliable prognostic biomarkers for the prediction of metastasis at diagnosis and the risk of relapse in clinical stage I (CSI) are lacking.
Bohle, Rainer M. +6 more
core +1 more source
ABSTRACT Background BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B) has been found to participate in cancer progression. Nevertheless, the function and mechanism of BUB1B in ovarian cancer (OC) remain unknown. Method Based on datasets GSE14407, GSE18520, and the TCGA combined GTEx database, the differently expressed genes (DEGs) between OC ...
Jing Wang, Xiaoling Su, Nan Lin, Tao Su
wiley +1 more source
A comprehensive method for identification of suitable reference genes in extracellular vesicles
Reverse transcription–quantitative polymerase chain reaction (RT-qPCR) is one of the most sensitive, economical and widely used methods for evaluating gene expression.
Kenneth Gouin +13 more
doaj +1 more source
Differentiation-Associated MicroRNA Alterations in Mouse Heart-Derived Sca-1 + [PDF]
Cardiac resident stem/progenitor cells (CSC/CPCs) are critical to the cellular and functional integrity of the heart because they maintain myocardial cell homeostasis.
Jinxi Zhan +7 more
core +2 more sources
Enhancing Late‐Life Survival and Mobility via Mitohormesis by Reducing Mitochondrial Calcium Levels
RNAi knockdown (KD) of mcu‐1 or mitoxantrone treatment lowers mitochondrial Ca2+, extends lifespan, and preserves motility during aging. Benefits require early intervention and involve a transient ROS increase that activates a pmk‐1, daf‐16, and skn‐1 pathway, enhancing stress defense and mitochondrial integrity while reducing early‐life survival ...
Doruntina Bresilla +13 more
wiley +1 more source
Both host and parasite non-coding RNAs co-ordinate the regulation of macrophage gene expression to reduce pro-inflammatory immune responses and promote tissue repair pathways during infection with fasciola hepatica. [PDF]
Parasitic worms (helminths) establish chronic infection within mammalian hosts by strategically regulating their host's immune responses. Deciphering the mechanisms by which host non-coding RNAs (ncRNA) co-ordinate the activation and regulation of immune
Chowdhury, S +4 more
core +1 more source

