Results 41 to 50 of about 45,933 (126)

Altered microRNA profile during fracture healing in rats with diabetes

open access: yesJournal of Orthopaedic Surgery and Research, 2020
Background MicroRNAs (miRNAs) are a class of small non-coding RNA molecules that regulate gene expression. There is increasing evidence that some miRNAs are involved in the pathology of diabetes mellitus (DM) and its complications.
Shunsuke Takahara   +11 more
doaj   +1 more source

Pro-fibrotic and apoptotic activities of circARAP1 in myocardial ischemia–reperfusion injury

open access: yesEuropean Journal of Medical Research, 2023
Reperfusion modality can cause damage to cardiomyocytes, known as myocardial ischemia–reperfusion injury (MI/RI). Circular RNAs (circRNAs) are fundamental regulators associated with many cardiac diseases, including MI/RI. However, their functional impact
Xi Li, Lei Guo, Jingjing Wang, Xing Yang
doaj   +1 more source

Evaluating the expression of miRNAs in the culture medium of human embryos with normal sex chromosomes and embryos with an X sex chromosome (Turner syndrome) [PDF]

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023
Introduction: Assisted reproductive techniques and Preimplantation Genetic Test (PGT) are performed to detect aneuploidy to achieve a euploid baby's birth in infertile or low-fertility couples.
Shahrzad Aghajani   +3 more
doaj  

microRNAs profiling of small extracellular vesicles from midbrain tissue of Parkinson’s disease

open access: yesFrontiers in Molecular Neuroscience, 2023
Small extracellular vesicles (sEVs) are generated by all types of cells during physiological or pathological conditions. There is growing interest in tissue-derived small extracellular vesicles (tdsEVs) because they can be isolated from a single tissue ...
Zhengzhe Li   +12 more
doaj   +1 more source

Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome

open access: yesFrontiers in Cell and Developmental Biology, 2021
Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno   +3 more
doaj   +1 more source

Extracellular Vesicles and Their miRNA Content in Amniotic and Tracheal Fluids of Fetuses with Severe Congenital Diaphragmatic Hernia Undergoing Fetal Intervention

open access: yesCells, 2021
Infants with congenital diaphragmatic hernia (CDH) are at high risk of postnatal mortality due to lung hypoplasia and arterial pulmonary hypertension.
Isabella Fabietti   +10 more
doaj   +1 more source

Identification of miRNA biomarkers for stomach adenocarcinoma

open access: yesBMC Bioinformatics, 2022
Background Stomach adenocarcinoma (STAD) is a common malignant tumor in the world and its prognosis is poor, miRNA plays a role mainly by influencing the expression of mRNAs, and participates in the occurrence and development of tumors. However, reliable
Hao Qian   +3 more
doaj   +1 more source

MicroRNA Signatures in Cartilage Ageing and Osteoarthritis

open access: yesBiomedicines, 2023
Osteoarthritis is the most common degenerative joint disorder. MicroRNAs are gene expression regulators that act post-transcriptionally to control tissue homeostasis.
Panagiotis Balaskas   +7 more
doaj   +1 more source

Androgen-induced exosomal miR-379-5p release determines granulosa cell fate: The cellular mechanism of anovulatory polycystic ovaries

open access: yes, 2023
Abstract Polycystic ovarian syndrome (PCOS) is a complex multi-factorial syndrome associated with androgen excess and anovulatory infertility. In the current study, we investigated the role of dihydrotestosterone-induced exosomal miR-379-5p release in determining the destiny of the developing follicles.
Reza Salehi   +19 more
openaire   +1 more source

Exosomal miRNA-223-3p derived from tumor associated macrophages promotes pulmonary metastasis of breast cancer 4T1 cells

open access: yesTranslational Oncology, 2023
Research about the effect of exosomes derived from tumor associated macrophages (TAM-exos) in the distant organ metastasis of breast cancer is limited. In this study, we found that TAM-exos could promote the migration of 4T1 cells.
Ziyuan Wang   +7 more
doaj   +1 more source

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