Functional Roles and Biological Mechanisms of Circular RNAs and Their Encoded Peptides in Glioma: A Narrative Review [PDF]
, 2021 Circular RNAs (circRNAs) are a complicated class of non-coding RNAs that have a covalently closed loop structure and are very stable and cautious. Multiple biological processes of malignancy, including tumorigenesis, development, invasion, metastasis ...
Bakhti, Seyedeh Zahra +3 more
core +2 more sources
Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome
Frontiers in Cell and Developmental Biology, 2021 Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno +3 more
doaj +1 more source
Regulation of microRNA during cardiomyocyte maturation in sheep. [PDF]
, 2015 BACKGROUND: There is a limited capacity to repair damage in the mammalian heart after birth, which is primarily due to the inability of cardiomyocytes to proliferate after birth.
Botting, Kimberley J +6 more
core +2 more sources
Expression profile of the chromosome 14 Microrna Cluster (C14MC) ortholog in equine maternal circulation throughout pregnancy and its potential implications [PDF]
, 2019 Equine chromosome 24 microRNA cluster (C24MC), the ortholog of human C14MC, is a pregnancy-related miRNA cluster. This cluster is believed to be implicated in embryonic, fetal, and placental development.
A. Ball, Barry +7 more
core +1 more source
Identification of miRNA biomarkers for stomach adenocarcinoma
BMC Bioinformatics, 2022 Background Stomach adenocarcinoma (STAD) is a common malignant tumor in the world and its prognosis is poor, miRNA plays a role mainly by influencing the expression of mRNAs, and participates in the occurrence and development of tumors. However, reliable
Hao Qian +3 more
doaj +1 more source
MicroRNA Signatures in Cartilage Ageing and Osteoarthritis
Biomedicines, 2023 Osteoarthritis is the most common degenerative joint disorder. MicroRNAs are gene expression regulators that act post-transcriptionally to control tissue homeostasis.
Panagiotis Balaskas +7 more
doaj +1 more source
Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria [PDF]
, 2016 Malaria remains one of the greatest public health challenges worldwide, particularly in sub-Saharan Africa. The clinical outcome of individuals infected with Plasmodium falciparum parasites depends on many factors including host systemic inflammatory ...
A Bhoumik +64 more
core +1 more source
To Detach, Migrate, Adhere, and Metastasize: CD97/ADGRE5 in Cancer [PDF]
, 2022 Tumorigenesis is a multistep process, during which cells acquire a series of mutations that lead to unrestrained cell growth and proliferation, inhibition of cell differentiation, and evasion of cell death.
Aust, Gabriela +2 more
core +2 more sources
Translational Oncology, 2023 Research about the effect of exosomes derived from tumor associated macrophages (TAM-exos) in the distant organ metastasis of breast cancer is limited. In this study, we found that TAM-exos could promote the migration of 4T1 cells.
Ziyuan Wang +7 more
doaj +1 more source
, 2023 Abstract Polycystic ovarian syndrome (PCOS) is a complex multi-factorial syndrome associated with androgen excess and anovulatory infertility. In the current study, we investigated the role of dihydrotestosterone-induced exosomal miR-379-5p release in determining the destiny of the developing follicles.
Reza Salehi +19 more
openaire +1 more source