Results 61 to 70 of about 45,933 (126)

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen   +12 more
wiley   +1 more source

MOV10 binding circ-DICER1 regulates the angiogenesis of glioma via miR-103a-3p/miR-382-5p mediated ZIC4 expression change

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background RNA binding proteins (RBPs) have been reported to interact with RNAs to regulate gene expression. Circular RNAs (circRNAs) are a type of endogenous non-coding RNAs, which involved in the angiogenesis of tumor.
Qianru He   +9 more
doaj   +1 more source

Small RNA Sequencing Uncovers New miRNAs and moRNAs Differentially Expressed in Normal and Primary Myelofibrosis CD34+ Cells. [PDF]

open access: yesPLoS ONE, 2015
Myeloproliferative neoplasms (MPN) are chronic myeloid cancers thought to arise at the level of CD34+ hematopoietic stem/progenitor cells. They include essential thrombocythemia (ET), polycythemia vera (PV) and primary myelofibrosis (PMF).
Paola Guglielmelli   +6 more
doaj   +1 more source

Advanced extracellular vesicle immunotherapy

open access: yesFlexMat, Volume 3, Issue 1, Page 117-143, March 2026.
A diagrammatic depiction of the therapeutic applicability of extracellular vesicles (EVs) in immunotherapy. This review explores the dual roles of tumor‐derived and immune cell‐derived EVs in cancer immunotherapy, discusses recent progress in EV engineering that improve their clinical utility, and evaluates their potential to augment existing ...
Jingjing Zhang   +6 more
wiley   +1 more source

EVALUATION OF THE PLASMA MICRO RNA EXPRESSION LEVELS IN SECONDARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2013
Background: Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hyper inflammatory disease. Micro RNAs (miRNA) are about 22 nucleotide-long, small RNAs encoded with genes, and they have regulatory functions in immune response.
Ali Bay   +5 more
doaj   +1 more source

Circulating microRNAs in patients with hormone receptor-positive, metastatic breast cancer treated with dovitinib

open access: yesClinical and Translational Medicine, 2017
Background Serial analysis of biomarkers in the circulation of patients undergoing treatment (“liquid biopsies”) can provide new insights into drug effects.
Narayan Shivapurkar   +4 more
doaj   +1 more source

Integrated Hypothalamic Transcriptome Profiling Reveals the Reproductive Roles of mRNAs and miRNAs in Sheep

open access: yesFrontiers in Genetics, 2020
Early studies have provided a wealth of information on the functions of microRNAs (miRNAs). However, less is known regarding their functions in the hypothalamus involved in sheep reproduction. To explore the potential roles of hypothalamic messenger RNAs
Zhuangbiao Zhang   +10 more
doaj   +1 more source

Differential expression of microRNAs in adipose tissue after long-term high-fat diet-induced obesity in mice. [PDF]

open access: yesPLoS ONE, 2012
Obesity is a major health concern worldwide which is associated with increased risk of chronic diseases such as metabolic syndrome, cardiovascular disease and cancer.
Dionysios V Chartoumpekis   +6 more
doaj   +1 more source

Changes in expression of miRNAs from the DLK1-DIO3 locus are characteristic of relapsing-remitting multiple sclerosis regardless of the disease activity

open access: yesНеврология, нейропсихиатрия, психосоматика, 2022
The role of miRNAs – small, regulatory, noncoding RNAs – in the multiple sclerosis (MS) development is being intensively investigated. Previously, we the first who observed a significant increase in the expression of 26 microRNA genes localized in the ...
N. M. Baulina   +3 more
doaj   +1 more source

Chromatin Accessibility in Cancer: Biological Functions, Mechanisms, Therapeutic Potential, and Future Directions

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia   +4 more
wiley   +1 more source

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