Results 171 to 180 of about 47,292 (192)

Circ_0007841 knockdown confers cisplatin sensitivity to ovarian cancer cells by down-regulation of NFIB expression in a miR-532-5p-dependent manner

Journal of Chemotherapy, 2022
Cisplatin (DDP) is first-line management for ovarian cancer (OC). Previous data have suggested that circular RNA_0007841 (circ_0007841) regulates OC progression; however, there is no data on its role in the sensitivity of OC cells to DDP.
Yuan Gao, Yan Huang
semanticscholar   +3 more sources

miR-532-5p Inhibits Non-Small Cell Lung Cancer Progression In Vivo and In Vitro by Targeting Yin Yang 1.

Critical Reviews in Eukaryotic Gene Expression, 2022
Lung cancer is a common cancer that is familiar to people and has the highest global incidence; among all lung cancer patients, 85% are non-small cell lung cancer (NSCLC).
Song Li, Chunling Zhu, Quandong Wang, Yong Wen   +3 more
semanticscholar   +3 more sources

MiR-532-5p alleviates hypoxia-induced cardiomyocyte apoptosis by targeting PDCD4.

Gene, 2018
MicroRNAs (miRNAs) are a class of endogenous non-coding RNAs involved in regulating various biological processes at the post-transcription level. Accumulating evidence suggests that hypoxia caused by acute myocardial infarction induces cardiomyocyte ...
Jideng Ma, Jinwei Zhang, Yujie Wang, K. Long, Xun Wang, L. Jin, Q. Tang, Li Zhu, G. Tang, Xuewei Li, Mingzhou Li   +10 more
semanticscholar   +3 more sources

LncRNA JHDM1D-AS1 promotes osteogenic differentiation of periodontal ligament cells by targeting miR-532-5p to activate IGF1R signaling.

Journal of Periodontal Research, 2023
OBJECTIVE The aim of this study was to explore the mechanism underlying periodontal ligament cells (PDLCs) osteogenic differentiation. BACKGROUND Periodontitis causes damage to tooth-supporting apparatus and eventually leads to tooth loss.
Xiaohuan Zhong, Huixin Wang
semanticscholar   +3 more sources

Bone marrow mesenchymal stem cells‐derived exosomes mediate nuclear receptor coactivator‐3 expression in osteoblasts by delivering miR‐532‐5p to influence osteonecrosis of the femoral head development

Cell Biology International, 2022
Exosomes (Exo) originated from bone marrow mesenchymal stem cells (BMSCs) have therapeutic impacts on osteonecrosis of the femoral head (ONFH), and microRNA (miR)‐532‐5p has been confirmed to participate in ONFH progression.
XiaoYong Lan, Haiping Ma, Yipin Xiong, Lingfeng Zou, Zhen Yuan, Yuhong Xiao   +5 more
semanticscholar   +3 more sources

circSKIL promotes osteoblastic differentiation of periodontal ligament cells by sponging miR-532-5p to activate Notch signaling.

Journal of Periodontal Research, 2022
BACKGROUND AND OBJECTIVE Periodontal ligament cells (PDLCs) possess the capacity to differentiate into a variety of cell types to benefit periodontal regeneration.
Xiaohuan Zhong, Huixin Wang
semanticscholar   +3 more sources

LncRNA TUG1 knockdown protects cardiomyocytes against hypoxia/reoxygenation-induced injury via regulating miR-532-5p/Sox8 axis.

Journal of Cardiovascular Pharmacology, 2020
Long non-coding RNA taurine upregulated gene 1 (lncRNA TUG1) has been reported to involve in the processing of cardiac ischemia/reperfusion (I/R) injury following myocardial infarction.
Xinyong Cai, S. Wang, Lan Hong, Songping Yu, Bin Li, H. Zeng, Xu Yang, Ping Zhang, Liang Shao   +8 more
semanticscholar   +3 more sources

YWHAE long non-coding RNA competes with miR-323a-3p and miR-532-5p through activating K-Ras/Erk1/2 and PI3K/Akt signaling pathways in HCT116 cells.

Human Molecular Genetics, 2019
YWHAE gene product belongs to the 14-3-3 protein family that mediates signal transduction in plants and mammals. A protein-coding and a non-coding RNA (lncRNA) transcripts have been reported for this gene in human.
Hassan Bjeije, B. Soltani, M. Behmanesh, M. Zali   +3 more
semanticscholar   +3 more sources

CircCHMP5 Contributes to Ox-LDL-induced Endothelial Cell Injury Through the Regulation of MiR-532-5p/ROCK2 axis

Cardiovascular Drugs and Therapy, 2022
Aberrant expression of circular RNA (circRNA) has been demonstrated to be related to atherosclerosis (AS) formation. However, the mechanism of circCHMP5 (also known as hsa_circ_0003575) in AS formation remains unclear.Oxidized low-density lipoprotein (ox-LDL) was used to treat human umbilical vein endothelial cells (HUVECs) to construct a cell injury ...
Xia Li, Xiaoli Kang, Yali Di, Shuxian Sun, Liming Yang, Bin Wang, Zheng Ji   +6 more
semanticscholar   +3 more sources

Two potential regulatory axes in breast cancer patients: hsa_circ_0001546/hsa-miR-532-5p/ZFHX3 and hsa_circ_0025244/hsa-miR-210-5p/BTG2

Cukurova Medical Journal
Purpose: This study aims to investigate the expression profiles of hsa_circ_0025244 and hsa_circ_0001546 in breast tissue samples and to propose potential regulatory axes for these circular RNAs.
Fahrunnisa Abanoz, Ilknur Suer, Murat Kaya, Asmaa Abuaisha, S. Emiroğlu, Ş. Öztürk   +5 more
semanticscholar   +2 more sources