Results 181 to 190 of about 5,056 (201)
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Long Noncoding RNA Taurine-Upregulated Gene 1 Knockdown Protects Cardiomyocytes Against Hypoxia/Reoxygenation-induced Injury Through Regulating miR-532-5p/Sox8 Axis

Journal of Cardiovascular Pharmacology, 2020
Background: Long noncoding RNA taurine-upregulated gene 1 (TUG1) has been reported to involve in the processing of cardiac ischemia/reperfusion injury after myocardial infarction. Thus, this study further investigates the underlying mechanisms of TUG1 in hypoxia/reoxygenation (H/R)-induced cardiomyocyte injury in vitro.
Xinyong, Cai   +8 more
openaire   +2 more sources

Abstract 2529: TTF-1/NKX2-1 induced miR-532-5p targets KRAS and MKL2 oncogenes and causes apoptosis in lung adenocarcinoma cells

Cancer Research, 2017
Abstract Our group and others have previously identified TTF-1/NKX2-1 as a lineage survival oncogene in lung adenocarcinoma. Subsequent studies revealed double-edged sword characteristics of TTF-1 in the development of lung adenocarcinoma.
Sebastian Griesing   +6 more
openaire   +1 more source

Effects of miR-532-5p on human brain microvascular endothelial cells damage induced by ox-LDL via down-regulating CLIC4 expression.

Pakistan journal of pharmaceutical sciences, 2021
The effect of miR-532-5p on human brain microvascular endothelial cells damage induced by ox-LDL is studied. HBMEC-3 were cultured and treated with ox-LDL for 24 h to establish a model of cell oxidative damage. The expression of miR-532-5p was detected by qRT-PCR and that of CLIC4 was detected by Western blot. miR-NC, miR-532-5p mimics, si-NC, si-CLIC4,
Qiping, Yao, Bei, Zhu
openaire   +1 more source

MiR‐532‐5p Attenuates Cognitive Deficits and Endoplasmic Reticulum Stress Subsequent to Polystyrene Microplastics

Environmental Toxicology
ABSTRACTThe increasing prevalence of microplastics pollution is a significant environmental challenge. However, the effects of these particles on learning and memory remain poorly understood. The aim of this investigation was to ascertain the influence of miR‐532‐5p on cognitive and memory deficits induced by polystyrene microplastics (PS‐MPs) and to ...
Leila Mohammadi   +4 more
openaire   +2 more sources

Role of pre-miR-532 (miR-532-5p and miR-532-3p) in regulation of gene expression and molecular pathogenesis in renal cell carcinoma.

American journal of clinical and experimental urology
Analyses of our previously determined microRNA (miRNA) expression signature of renal cell carcinoma (RCC) and The Cancer Genome Atlas (TCGA) database revealed that both strands of the pre-miR-532-duplex-miR-532-5p (the guide strand) and miR-532-3p (the passenger strand)- are closely associated with poor prognosis of RCC patients (P = 0.0411 and P = 0 ...
Yasutaka, Yamada   +8 more
openaire   +1 more source

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