Results 181 to 186 of about 4,926 (186)
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Journal of Periodontal Research, 2022
AbstractBackground and objectivePeriodontal ligament cells (PDLCs) possess the capacity to differentiate into a variety of cell types to benefit periodontal regeneration. In this study, we examined the circSKIL/miR‐532‐5p/Notch1 axis in controlling the osteoblastic differentiation of PDLCs.MethodsPrimary human PDLCs (hPDLCs) were isolated and induced ...
Xiaohuan, Zhong, Huixin, Wang
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AbstractBackground and objectivePeriodontal ligament cells (PDLCs) possess the capacity to differentiate into a variety of cell types to benefit periodontal regeneration. In this study, we examined the circSKIL/miR‐532‐5p/Notch1 axis in controlling the osteoblastic differentiation of PDLCs.MethodsPrimary human PDLCs (hPDLCs) were isolated and induced ...
Xiaohuan, Zhong, Huixin, Wang
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Journal of Periodontal Research, 2023
AbstractObjectiveThe aim of this study was to explore the mechanism underlying periodontal ligament cells (PDLCs) osteogenic differentiation.BackgroundPeriodontitis causes damage to tooth‐supporting apparatus and eventually leads to tooth loss. PDLCs hold great promise in periodontal regeneration due to their osteogenic features.MethodsThe expression ...
Xiaohuan, Zhong, Huixin, Wang
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AbstractObjectiveThe aim of this study was to explore the mechanism underlying periodontal ligament cells (PDLCs) osteogenic differentiation.BackgroundPeriodontitis causes damage to tooth‐supporting apparatus and eventually leads to tooth loss. PDLCs hold great promise in periodontal regeneration due to their osteogenic features.MethodsThe expression ...
Xiaohuan, Zhong, Huixin, Wang
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Inflammation, 2012
MicroRNAs (miRNAs) are short non-coding RNAs that are involved in the epigenetic regulation of cellular processes. To identify more miRNAs which are involved in the macrophage inflammatory response to lipopolysaccharide (LPS) stimulation and dissect the mechanisms more clearly, microRNA profiling of LPS-treated RAW264.7 macrophage cells was performed ...
Ying, Cheng +8 more
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MicroRNAs (miRNAs) are short non-coding RNAs that are involved in the epigenetic regulation of cellular processes. To identify more miRNAs which are involved in the macrophage inflammatory response to lipopolysaccharide (LPS) stimulation and dissect the mechanisms more clearly, microRNA profiling of LPS-treated RAW264.7 macrophage cells was performed ...
Ying, Cheng +8 more
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Cancer Research, 2017
Abstract Our group and others have previously identified TTF-1/NKX2-1 as a lineage survival oncogene in lung adenocarcinoma. Subsequent studies revealed double-edged sword characteristics of TTF-1 in the development of lung adenocarcinoma.
Sebastian Griesing +6 more
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Abstract Our group and others have previously identified TTF-1/NKX2-1 as a lineage survival oncogene in lung adenocarcinoma. Subsequent studies revealed double-edged sword characteristics of TTF-1 in the development of lung adenocarcinoma.
Sebastian Griesing +6 more
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Pakistan journal of pharmaceutical sciences, 2021
The effect of miR-532-5p on human brain microvascular endothelial cells damage induced by ox-LDL is studied. HBMEC-3 were cultured and treated with ox-LDL for 24 h to establish a model of cell oxidative damage. The expression of miR-532-5p was detected by qRT-PCR and that of CLIC4 was detected by Western blot. miR-NC, miR-532-5p mimics, si-NC, si-CLIC4,
Qiping, Yao, Bei, Zhu
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The effect of miR-532-5p on human brain microvascular endothelial cells damage induced by ox-LDL is studied. HBMEC-3 were cultured and treated with ox-LDL for 24 h to establish a model of cell oxidative damage. The expression of miR-532-5p was detected by qRT-PCR and that of CLIC4 was detected by Western blot. miR-NC, miR-532-5p mimics, si-NC, si-CLIC4,
Qiping, Yao, Bei, Zhu
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American journal of clinical and experimental urology
Analyses of our previously determined microRNA (miRNA) expression signature of renal cell carcinoma (RCC) and The Cancer Genome Atlas (TCGA) database revealed that both strands of the pre-miR-532-duplex-miR-532-5p (the guide strand) and miR-532-3p (the passenger strand)- are closely associated with poor prognosis of RCC patients (P = 0.0411 and P = 0 ...
Yasutaka, Yamada +8 more
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Analyses of our previously determined microRNA (miRNA) expression signature of renal cell carcinoma (RCC) and The Cancer Genome Atlas (TCGA) database revealed that both strands of the pre-miR-532-duplex-miR-532-5p (the guide strand) and miR-532-3p (the passenger strand)- are closely associated with poor prognosis of RCC patients (P = 0.0411 and P = 0 ...
Yasutaka, Yamada +8 more
openaire +1 more source