Results 181 to 190 of about 47,292 (192)

Neuroprotective effects of miR-532-5p against ischemic stroke

Metabolic Brain Disease, 2020
Stroke can cause death and disability and has a high incidence with many complications. So far, effective treatment options for stroke are still limited. MicroRNA-532-5p (miR-532-5p) is significantly downregulated in stroke. However, the role of miR-532-5p in ischemic stroke is still unclear.
Jingwei Mu, Xi Cheng, Shanshan Zhong, Xiaohong Chen, Chuansheng Zhao   +4 more
semanticscholar   +3 more sources

MiR-532-5p acts as a tumor suppressor and inhibits glioma cell proliferation by targeting CSF1.

European review for medical and pharmacological sciences, 2020
Since this article has been suspected of research misconduct and the corresponding authors did not respond to our request to prove originality of data and figures, "MiR-532-5p acts as a tumor suppressor and inhibits glioma cell proliferation by targeting CSF1, by Y.-P. Wang, J. Liu, D. Liu, X.-D. Wang, A.-M. Bian, D.-Z. Fang, X.-B.
Y.-P. Wang, J. Liu, D. Liu, X. Wang, A-M Bian, Dazhao Fang, Xiao-bo Hui   +6 more
semanticscholar   +4 more sources

miR-532-5p is a prognostic marker and suppresses cells proliferation and invasion by targeting TWIST1 in epithelial ovarian cancer.

European review for medical and pharmacological sciences, 2018
Dysregulated miR-532-5p has been observed in epithelial ovarian cancer (EOC). However, the potential biological function and clinical significance have not been fully explained. The study aimed to investigate the prognostic value and potential role of miR-532-5p in EOC.MiR-532-5p and Twist homolog 1 (TWIST1) mRNA expression were examined using ...
H. Wei, Q. Tang, K. Zhang, J-J Sun, R. Ding   +4 more
semanticscholar   +3 more sources

A genetic variant located in the miR-532-5p-binding site of TGFBR1 is associated with the colorectal cancer risk

Journal of Gastroenterology, 2018
Genome-wide association studies have identified genes in the transforming growth factor-β (TGFβ) signaling pathway that are responsible for regulating carcinogenesis.We searched for single-nucleotide polymorphisms (SNPs) located within 3'-untranslated regions (3'-UTRs) that might affect the ability of miRNAs to bind genes in the TGFβ pathway for ...
D. Gu, Shuwei Li, Mulong Du, Cuiju Tang, H. Chu, N. Tong, Zhengdong Zhang, Meilin Wang, Jinfei Chen   +8 more
semanticscholar   +3 more sources

Downregulation of miR-27a* and miR-532-5p and Upregulation of miR-146a and miR-155 in LPS-induced RAW264.7 Macrophage Cells

Inflammation, 2012
MicroRNAs (miRNAs) are short non-coding RNAs that are involved in the epigenetic regulation of cellular processes. To identify more miRNAs which are involved in the macrophage inflammatory response to lipopolysaccharide (LPS) stimulation and dissect the mechanisms more clearly, microRNA profiling of LPS-treated RAW264.7 macrophage cells was performed ...
Ying Cheng, Wenhua Kuang, Yongchang Hao, Donglin Zhang, Ming Lei, Li Du, Hanwei Jiao, Xiaoru Zhang, Fengyang Wang   +8 more
semanticscholar   +4 more sources

Abstract 2529: TTF-1/NKX2-1 induced miR-532-5p targets KRAS and MKL2 oncogenes and causes apoptosis in lung adenocarcinoma cells

Cancer Research, 2017
Abstract Our group and others have previously identified TTF-1/NKX2-1 as a lineage survival oncogene in lung adenocarcinoma. Subsequent studies revealed double-edged sword characteristics of TTF-1 in the development of lung adenocarcinoma.
Sebastian Griesing, Taisuke Kajino, M. Tai, Zhuoran Liu, M. Nakatochi, Motoshi Suzuki, Takashi Takahashi   +6 more
semanticscholar   +2 more sources

MiR‐532‐5p Attenuates Cognitive Deficits and Endoplasmic Reticulum Stress Subsequent to Polystyrene Microplastics

Environmental Toxicology
The increasing prevalence of microplastics pollution is a significant environmental challenge. However, the effects of these particles on learning and memory remain poorly understood.
Leila Mohammadi, T. Baluchnejadmojarad, Mina Goudarzi, Vahid Khodashenas, M. Roghani   +4 more
semanticscholar   +1 more source

Effects of miR-532-5p on human brain microvascular endothelial cells damage induced by ox-LDL via down-regulating CLIC4 expression.

Pakistan journal of pharmaceutical sciences, 2021
The effect of miR-532-5p on human brain microvascular endothelial cells damage induced by ox-LDL is studied. HBMEC-3 were cultured and treated with ox-LDL for 24 h to establish a model of cell oxidative damage. The expression of miR-532-5p was detected by qRT-PCR and that of CLIC4 was detected by Western blot. miR-NC, miR-532-5p mimics, si-NC, si-CLIC4,
Qiping, Yao, Bei, Zhu
openaire   +1 more source

Role of pre-miR-532 (miR-532-5p and miR-532-3p) in regulation of gene expression and molecular pathogenesis in renal cell carcinoma.

American journal of clinical and experimental urology
Analyses of our previously determined microRNA (miRNA) expression signature of renal cell carcinoma (RCC) and The Cancer Genome Atlas (TCGA) database revealed that both strands of the pre-miR-532-duplex-miR-532-5p (the guide strand) and miR-532-3p (the passenger strand)- are closely associated with poor prognosis of RCC patients (P = 0.0411 and P = 0 ...
Yasutaka, Yamada, Takayuki, Arai, Mayuko, Kato, Satoko, Kojima, Shinichi, Sakamoto, Akira, Komiya, Yukio, Naya, Tomohiko, Ichikawa, Naohiko, Seki   +8 more
openaire   +1 more source

MicroRNA-532-5p upregulation protects neurological deficits after ischemic stroke through inhibition of BTB and CNC homology 1.

International Immunopharmacology, 2021
Jing Wang, Bin Han, Xiaoli Zhao, Yaxuan Sun, Yi Liu, F. Hu, Kun Meng   +6 more
semanticscholar   +1 more source