Results 91 to 100 of about 255,804 (230)

Circular RNA hsa_circRNA_101996 modulates gastric cancer cell proliferation and apoptosis through the miR-577/HMGN5 axis

World Journal of Gastrointestinal Oncology
BACKGROUND Circular RNAs (circRNAs) are critical regulators in tumorigenesis, functioning as microRNA sponges or protein decoys. Although numerous circRNAs have been implicated in gastric cancer progression, the role of hsa_circRNA_101996 remains unclear.
Wang, Xiao-Lei, Zhang, Lin, Shang, Qing
openaire   +2 more sources

STAT3-induced upregulation of lncRNA DUXAP8 functions as ceRNA for miR-577 to promote the migration and invasion in colorectal cancer through the regulation of RAB14.

European review for medical and pharmacological sciences, 2019
Previous reports have shown that long non-coding RNAs (lncRNAs) are involved in a series of biological processes and cancer in humans. Recently, lncRNA double homeobox A pseudogene 8 (DUXAP8) was frequently reported to be aberrantly expressed in multiple cancers and play a functional role.
Du, C., Wang, H.-X., Chen, P., Chen, C.-H.   +3 more
openaire   +2 more sources

Stress responsive miR-23a attenuates skeletal muscle atrophy by targeting MAFbx /atrogin-1 [PDF]

, 2008
Muscle atrophy occurs in many pathological states and results primarily from accelerated protein degradation by the ubiquitin-proteasome pathway. We used dexamethasone to induce muscle wasting and investigated the role of a microRNA (miRNA) in the ...
Shigeru Miyaki, Yoshio Kato, Shogo Wada, Zhen Yan, Katsuhiko Suzuki, Takashi Ushida, Takayuki Akimoto, Mitsuharu Okutsu, Hiroshi Asahara   +8 more
core  

List of predicted top murine targets of mmu-miR-711, mmu-miR-2137, and mmu-miR-710.

, 2019
a. The predicted targets of miR-711 clustered with genes related to apoptosis, angiogenesis, cell adhesion, and immune regulation. The predicted targets of miRNA-2137 clustered with drug resistance and proliferation.
Nikhil Meka (8124602), Patrick Sheedy (8124605), Pamela Pantazopoulos (2528401), Byunghee Yoo (2346787), Zdravka Medarova (2229724), Ann-Marie Billig (8124608)   +5 more
core   +1 more source

 miR-577 inhibits pancreatic β-cell function and survival by targeting fibroblast growth factor 21 (FGF-21) in pediatric diabetes

Genetics and Molecular Research, 2015
Pancreatic β-cell dysfunction is a central component of the pathogenesis of pediatric diabetes. MicroRNA (miRNA) have become one of the most encouraging and fruitful fields in biological research, and have been implicated as new players in the pathogenesis of diabetes and diabetes-associated complications.
X Y, Chen, G M, Li, Q, Dong, H, Peng
openaire   +2 more sources

Effects of intermittent exposure to hypobaria and cold on the microarchitecture and morphofunctional profile of rat gastrocnemius muscle

The Anatomical Record, EarlyView.
Abstract Intermittent hypobaric hypoxia (IHH) enhances oxygen transport, muscle metabolism, and cardiovascular health; however, the combined effects of hypobaria and cold are less well understood. Exposure to these stressful environmental factors, even intermittently, can affect skeletal muscle due to its plasticity, thereby altering its metabolic and ...
Garoa Santocildes, Teresa Pagès, Ginés Viscor, Joan Ramon Torrella   +3 more
wiley   +1 more source

MicroRNA-mediated modulation of signalling pathways in lung cancer: implications for diagnosis and treatment

Journal of Basic and Applied Zoology
Background As the leading cause of cancer-related deaths worldwide, lung cancer (LC) continues to be a significant public health concern. These microscopic non-coding RNAs (ncRNA), also known as microRNAs (miRNAs), are essential for controlling gene ...
Mogeshwaran Appasamy, Prakavi Kirubaharan, Vijayalakshmi Sulluru, Thirunavukkarasu Palaniyandi, Gomathy Baskar, Mugip Rahaman Abdul Wahab   +5 more
doaj   +1 more source

MicroRNAs and predicted targets in the switch from monolayered to spheroids of cholangiocarcinoma cells

Experimental and Molecular Pathology
Background: Extrahepatic cholangiocarcinoma (eCCA) is characterized by marked molecular heterogeneity and limited therapeutic options. MicroRNAs (miRNAs) are key post-transcriptional regulators of cancer-related pathways, but their contribution to tumor ...
Leda Roncoroni, Anna Terrazzan, Luca Elli, Pietro Ancona, Paula Olaizola, Silvia Tabano, Patrizia Colapietro, Filippo Gamberini, Chiara Orlandi, Gianluca Aguiari, Cristian Taccioli, Luisa Doneda, Nicoletta Bianchi   +12 more
doaj   +1 more source

anamud/mir-dev: MIR v1.0.0

, 2017
<p>This is the first release of MIR, hence v1.0.0.</p> <p>MIR is a task-based runtime system library specialized for high performance execution and detailed yet cost-effective profiling of OpenMP programs.</p> <p>Fork the ...
Peter A. Jonsson, Peder Langdal, Ananya Muddukrishna   +2 more
core   +1 more source

Exploring the cranial morphology and possible convergences of Triassic non‐crocodylomorph pseudosuchians (Archosauria: Pseudosuchia) with other sauropsids through linear morphometrics

The Anatomical Record, EarlyView.
Abstract Triassic pseudosuchians had highly diversified cranial morphologies. These archosaurs occupied diverse ecological roles, ranging from terrestrial predators and herbivores to semiaquatic ambush predators and possible waders. Here, we apply linear cranial morphometrics to assess possible convergences with other sauropsids from the clades ...
Rafael Terras, Rodrigo Temp Müller, Leonardo Kerber, Mirian Carbonera   +3 more
wiley   +1 more source