Results 201 to 210 of about 255,804 (230)

SP1-induced overexpression of LINC00520 facilitates non-small cell lung cancer progression through miR-577/CCNE2 pathway and predicts poor prognosis

Human Cell, 2021
Long noncoding RNAs (lncRNAs) have gained much attention in the past few years. Long intergenic non-protein coding RNA 520 (LINC00520) was one of the newly discovered lncRNA which has been demonstrated to be dysregulated in several cancers. So far, the function and mechanism of LINC00520 in non-small cell lung cancer (NSCLC) are unclear. In this paper,
Ji-fang Wang, Zhuo-na Xi, Hong-jian Su, Zhen Bao, Ya-hong Qiao   +4 more
openaire   +2 more sources

miR-577 inhibits glioblastoma tumor growth via the Wnt signaling pathway.

Molecular carcinogenesis, 2016
microRNAs (miRNAs) are commonly altered in glioblastoma. Publicly available algorithms suggest the Wnt pathway is a potential target of miR-577 and the Wnt pathway is commonly altered in glioblastoma. Glioblastoma has not been previously evaluated for miR-577 expression. Glioblastoma tumors and cell lines were evaluated for their expression of miR-577.
Weiguang, Zhang, Chen, Shen, Chenguang, Li, Guang, Yang, Huailei, Liu, Xin, Chen, Dan, Zhu, Huichao, Zou, Yunbo, Zhen, Daming, Zhang, Shiguang, Zhao   +10 more
openaire   +1 more source

Up-regulated lnc-SNHG1 contributes to osteosarcoma progression through sequestration of miR-577 and activation of WNT2B/Wnt/β-catenin pathway

Biochemical and Biophysical Research Communications, 2018
Long noncoding RNA small nucleolar RNA host gene 1 (lnc-SNHG1) was reported to play an oncogenic role in the progression of cancers. However, the roles of SNHG1 and its molecular mechanism in osteosarcoma (OS) cells are largely unknown. In present study, we found that the expression of SNHG1 was up-regulated in OS tissues and cell lines.
Zhe, Jiang, Chunshan, Jiang, Jinnv, Fang
openaire   +2 more sources

Mechanism of PWAR6 regulating cisplatin drug sensitivity in non-small cell lung cancer through miR-577/PHACTR1

Gene
lncRNA Prader Willi/Angelman Region RNA 6 (PWAR6) is considered to play a protective lncRNA in glioma, but, the role of PWAR6 in the occurrence and cisplatin resistance of non-small cell lung cancer (NSCLC) is elusive. In the study, we aimed to assess the role of PWAR6 in the cisplatin resistance of NSCLC.
Wenjun, Tang, Jingru, Luo, Shu, Lin, Junnv, Xu, Qixing, Yan   +4 more
openaire   +2 more sources

Long non-protein coding RNA DANCR functions as a competing endogenous RNA to regulate osteoarthritis progression via miR-577/SphK2 axis

Biochemical and Biophysical Research Communications, 2018
Long noncoding RNAs (lncRNAs) have been known to be involved in multiple diverse diseases, including osteoarthritis (OA). This study aimed to explore the role of differentiation antagonizing non-protein coding RNA (DANCR) in OA and identify the potential molecular mechanisms.
Xiaochen, Fan, Jishan, Yuan, Jun, Xie, Zhanpeng, Pan, Xiang, Yao, Xiangyi, Sun, Pin, Zhang, Lei, Zhang   +7 more
openaire   +2 more sources

Exploring miR‐577 and miR‐494‐3p as Emerging Biomarkers in Sepsis‐Associated Acute Kidney Injury: Diagnostic and Prognostic Perspectives

Microbiology and Immunology
ABSTRACT Sepsis‐associated acute kidney injury (AKI) poses a severe threat to patients' lives and health, making early predictions, intervention, and treatment crucial. This study aims to preliminarily explore the clinical role of miR‐577 and miR‐494‐3p in sepsis‐associated AKI.
Lixia, Xu, Jingpo, Li, Li, Li, Qiushuang, Zhang, Qiuju, Feng, Lijie, Bai   +5 more
openaire   +2 more sources

Crocin suppressed cell proliferation and migration by regulating miR-577/NFIB in renal cell carcinoma.

JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2020
L, Niu, X F, Wang, X R, Wang
openaire   +2 more sources

MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH

Cell Metabolism, 2022
Wei Ying, Jerrold Olefsky, Zhongmou Jin   +2 more
exaly  

miR-577 inhibits glioblastoma tumor growth via the Wnt signaling pathway

Molecular Carcinogenesis, 2015
Weiguang Zhang, Chen Shen, Chenguang Li, Guang Yang, Huailei Liu, Xin Chen, Dan Zhu, Huichao Zou, Yunbo Zhen, Daming Zhang, Shiguang Zhao   +10 more
openaire   +1 more source

[The Targeted Regulating Role of Has-miR-577 and Has-miR-583 on Gene FGF-21 Detected by the Dual Luciferase Reporter System.]

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2018
To determine the targeted regulating role of has-miR-577 and has-miR-583 on the expression of fibroblast growth factor 21 (FGF-21) based on a constructed luciferase reporter FGF-21 gene vector.The site of has-miR-577 and has-miR-583 target genes FGF-21 were predicted by the bioinformatics analyzing tools online.FGF-21 gene fragments,combined with has ...
Mei, Zhang, He, He, Hao-Lan, Song, Jun, Zhou, Heng-Jian, Huang, Bin-Wu, Ying, Zhen-Mei, An   +6 more
openaire   +1 more source