LncRNA NEAT1 promotes apoptosis and inflammation in LPS-induced sepsis models by targeting miR-590-3p. [PDF]
Exp Ther Med, 2020 Sepsis is a complication of infection caused by disease or trauma. Increasing evidence have shown that long noncoding RNAs (lncRNAs) are involved in the regulation of sepsis. However, the mechanism of lncRNA nuclear enriched abundant transcript 1 (NEAT1) in the regulation of sepsis progression remains to be elucidated. Lipopolysaccharide (LPS) was used
Liu L +5 more
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MiR-590-3p regulates proliferation, migration and collagen synthesis of cardiac fibroblast by targeting ZEB1. [PDF]
J Cell Mol Med, 2020 AbstractPrevious studies have implicated the attractive and promising role of miR‐590‐3p to restore the cardiac function following myocardial infarction (MI). However, the molecular mechanisms for how miR‐590‐3p involves in cardiac fibrosis remain largely unexplored. Using human cardiac fibroblasts (HCFs) as the cellular model, luciferase report assay,
Yuan X +9 more
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Investigative Opthalmology & Visual Science, 2019 To elucidate the mechanism whereby miR-590-3p regulates pyroptosis in diabetic retinopathy (DR).Human retinal microvascular endothelial cells (HRMECs) incubated with high glucose (HG) were used to establish cell models, and the expression levels of miR-590-3p, caspase-1, IL-1β, NLRP1, NOX4, TXNIP, NLRP3, and ROS were determined.
Chufeng Gu +8 more
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miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18 [PDF]
AGE, 2014 Previously, AIMP3 (aminoacyl-tRNAsynthetase-interacting multifunctional protein-3) was shown to be involved in the macromolecular tRNA synthetase complex or to act as a tumor suppressor. In this study, we report a novel role of AIMP3/p18 in the cellular aging of human mesenchymal stem cells (hMSCs).
Seunghee Lee +9 more
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MicroRNA (miR)-590-3p alleviates high-glucose induced renal tubular epithelial cell damage by targeting C-X3-C motif chemokine ligand 1 (CX3CL1) in diabetic nephropathy. [PDF]
Bioengineered, 2022 Yun J +7 more
europepmc +1 more source
Discover OncologyBackground 5-fluorouracil (5-FU) is conventionally used in chemotherapy for colon adenocarcinomas. Acquired resistance of 5-FU remains a clinical challenge in colon cancer, and efforts to develop targeted agents to reduce resistance have not yielded ...
Zhongshi Hong +7 more
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Figure S4 from miR-590-3p Promotes Ovarian Cancer Growth and Metastasis via a Novel FOXA2–Versican Pathway [PDF]
, 2023 Mohamed E. Salem +11 more
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The Wnt Signalling Pathway: A Tailored Target in Cancer [PDF]
, 2020 Brizzi, Mf, Koni, M, Pinnarò, V
core +1 more source
Long Non-Coding RNA HAND2-AS1 Inhibits Growth and Migration of Gastric Cancer Cells Through Regulating the miR-590-3p/KCNT2 Axis [Retraction]. [PDF]
Onco Targets Ther, 2021 europepmc +1 more source
Hsa-MiR-590-3p Promotes the Malignancy Progression of Pancreatic Ductal Carcinoma by Inhibiting the Expression of p27 and PPP2R2A via G1/S Cell Cycle Pathway. [PDF]
Onco Targets Ther, 2020 Shi X, Sheng W, Jia C, Tang J, Dong M.
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