Results 31 to 40 of about 4,084 (142)

The circ_0054633/miR-590-3p/RUNX2 positive feedback loop promotes the osteogenic differentiation of BMSCs. [PDF]

open access: goldStem Cell Res Ther
Wang L   +10 more
europepmc   +2 more sources

LncRNA NEAT1 promotes apoptosis and inflammation in LPS-induced sepsis models by targeting miR-590-3p. [PDF]

open access: yesExp Ther Med, 2020
Sepsis is a complication of infection caused by disease or trauma. Increasing evidence have shown that long noncoding RNAs (lncRNAs) are involved in the regulation of sepsis. However, the mechanism of lncRNA nuclear enriched abundant transcript 1 (NEAT1) in the regulation of sepsis progression remains to be elucidated. Lipopolysaccharide (LPS) was used
Liu L   +5 more
europepmc   +5 more sources

MiR-590-3p regulates proliferation, migration and collagen synthesis of cardiac fibroblast by targeting ZEB1. [PDF]

open access: yesJ Cell Mol Med, 2020
AbstractPrevious studies have implicated the attractive and promising role of miR‐590‐3p to restore the cardiac function following myocardial infarction (MI). However, the molecular mechanisms for how miR‐590‐3p involves in cardiac fibrosis remain largely unexplored. Using human cardiac fibroblasts (HCFs) as the cellular model, luciferase report assay,
Yuan X   +9 more
europepmc   +4 more sources

Che-1/miR-590-3p/TAZ axis sustains multiple myeloma disease. [PDF]

open access: yesLeukemia
Multiple myeloma (MM) is a blood disease characterized by the malignant accumulation of monoclonal plasma cells in the bone marrow. Among the pathological consequences of the MM, defects in osteogenesis characterized by osteolytic lesions, osteopenia, and pathologic fractures are frequently described.
Bruno T   +13 more
europepmc   +2 more sources

miR-590-3pInhibits Pyroptosis in Diabetic Retinopathy by TargetingNLRP1and Inactivating the NOX4 Signaling Pathway

open access: goldInvestigative Opthalmology & Visual Science, 2019
To elucidate the mechanism whereby miR-590-3p regulates pyroptosis in diabetic retinopathy (DR).Human retinal microvascular endothelial cells (HRMECs) incubated with high glucose (HG) were used to establish cell models, and the expression levels of miR-590-3p, caspase-1, IL-1β, NLRP1, NOX4, TXNIP, NLRP3, and ROS were determined.
Chufeng Gu   +8 more
openalex   +3 more sources

MiR-590-3p promotes proliferation and metastasis of colorectal cancer via Hippo pathway. [PDF]

open access: yesOncotarget, 2017
Studies reported that miR-590-3p was involved in human cancer progression. However, its roles of oncogene or anti-oncogene in malignancies still remain elusive. This study was aimed to investigate the effect of miR-590-3p on the cell proliferation and metastasis via Hippo pathway in colorectal cancer (CRC).
Sun ZQ   +11 more
europepmc   +4 more sources

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