MiR-590-3p suppresses hepatocellular carcinoma growth by targeting TEAD1
MicroRNA signature is altered in different disease states including cancer, and some microRNAs act as oncogenes or tumor suppressors. MiR-590-3p has been shown to be involved in human cancer progression.
Xin Ge, Liansheng Gong
doaj +1 more source
Stem cells have two important features, namely the ability for self-renewal and the capacity to differentiate into some cell kinds with specialized functions. These two features are also present in cancer stem cells (CSCs). These cells have been detected
Soudeh Ghafouri-Fard+5 more
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Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules [PDF]
Understanding the molecular mechanisms regulating cardiac cell proliferation during the embryonic, fetal and adult life holds a paramount importance in view of developing innovative strategies aimed at inducing myocardial regeneration after cardiac ...
Torrini, Consuelo
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Objective To investigate the expression of long non-coding RNA (LncRNA) HCG11 and miR-590-3p in squamous carcinoma of cervix and paired adjacent tissues, and their correlation with patients' clinical data and prognosis.
CHEN Xiaojie, LIU Ping
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A statistically inferred microRNA network identifies breast cancer target miR-940 as an actin cytoskeleton regulator [PDF]
International audienceMiRNAs are key regulators of gene expression. By binding to many genes, they create a complex network of gene co-regulation. Here, using a network-based approach, we identified miRNA hub groups by their close connections and common ...
Bhajun, Ricky+9 more
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Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto
Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih+2 more
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The Effect of Chemotherapy in Gestational Trophoblastic Disease on Infertility: A Review on Pathophysiologic Mechanism [PDF]
Today, young women infertility through chemotherapy has become a global challenge. Chemotherapy destructs the malignant cells by reactive oxygen species (ROS) production and inflammatory factors secretion; these factors can also destruct the ovarian and ...
Ebrahimi, Maryam+5 more
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Profiling microRNAs in individuals at risk of progression to rheumatoid arthritis [PDF]
Background: Individuals at risk of rheumatoid arthritis (RA) demonstrate systemic autoimmunity in the form of anti-citrullinated peptide antibodies (ACPA). MicroRNAs (miRNAs) are implicated in established RA.
AV Churov+28 more
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Endometriosis-derived exosomes encapsulated miR-196a-5p mediate macrophage polarization through regulation of the Hippo pathway. [PDF]
Encapsulation of miR‐196a‐5p mimic in serum‐derived exosomes from patients with endometriosis by electrotransfection: exosomes encapsulated with miR‐196a‐5p are phagocytosed by macrophages and release miR‐196a‐5p; miR‐196a‐5p activates the Hippo pathway and promotes macrophage M1‐type polarization, thereby inhibiting 12Z cell metastasis.
Lu B, Huang Q, Zhong Y.
europepmc +2 more sources
Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors
Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou+7 more
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