Results 51 to 60 of about 4,084 (142)
miR-543 and miR-590-3p regulate human mesenchymal stem cell aging via direct targeting of AIMP3/p18 [PDF]
AGE, 2014 Previously, AIMP3 (aminoacyl-tRNAsynthetase-interacting multifunctional protein-3) was shown to be involved in the macromolecular tRNA synthetase complex or to act as a tumor suppressor. In this study, we report a novel role of AIMP3/p18 in the cellular aging of human mesenchymal stem cells (hMSCs).
Seunghee Lee +9 more
openalex +5 more sources
miR-590-3p is a novel microRNA which suppresses osteosarcoma progression by targeting SOX9
Biomedicine & Pharmacotherapy, 2018 Osteosarcoma is the most common primary bone malignancy and arises primarily in the metaphyseal ends of long bones in children and adolescents. m iR-590 has been found to have anti-tumor effects in many other cancers. However, the role of miR-590-3p in osteosarcoma is poorly understood. In this study, we show that miR-590-3p was significantly decreased
Peng Zhao +5 more
openaire +3 more sources
Zhongliu Fangzhi Yanjiu, 2018 Objective To investigate the expression of long non-coding RNA (LncRNA) HCG11 and miR-590-3p in squamous carcinoma of cervix and paired adjacent tissues, and their correlation with patients' clinical data and prognosis.
CHEN Xiaojie, LIU Ping
doaj +1 more source
Acta Biochimica Polonica, 2020 Background: MicroRNAs play a crucial role in diabetic peripheral neuropathic pain (DPNP). miR-590-3p is a novel miRNA and involved in multiple diseases. However, the pathological mechanism of miR-590-3p in DPNP needs to be elucidated. Materials and methods: The db/db mice and db/m mice were selected to mimic diabetes and control, respectively, for in ...
Yihua Wu, Ye Gu, Bimin Shi
openaire +3 more sources
Profil Ekspresi MikroRNA Kanker Payudara di Purwokerto
Jurnal Kesehatan Andalas, 2021 Penemuan metode deteksi dini kanker payudara secara sensitif, spesifik dan minimal invasif merupakan kunci dalam keberhasilan pengobatan. Hal ini dapat dilakukan menggunakan biomarker yang bersirkulasi dalam plasma darah yaitu mikroRNA.
Ari Dwi Nurasih +2 more
doaj +1 more source
Potential Value of Circular RNA circTBC1D4 in Gastrointestinal Stromal Tumors
Journal of Immunology Research, 2022 Aims. To explore the expression of circular RNA (circRNA) in gastrointestinal stromal tumors. Background. Gastrointestinal stromal tumors (GIST) are mainly distributed in the stomach and small intestine.
null Chunyan-Zou +7 more
doaj +1 more source
Coordinated Expressional Landscape of the Human Placental miRNome and Transcriptome
Frontiers in Cell and Developmental Biology, 2021 Placenta is a unique organ that serves its own function, and contributes to maternal gestational adaptation and fetal development. Coordination of its transcriptome to satisfy all the maternal-fetal needs across gestation is not fully understood ...
Rain Inno +3 more
doaj +1 more source
Discovery of Novel miRNAs in Colorectal Cancer: Potential Biological Roles and Clinical Utility
Non-Coding RNA, 2023 Deregulated miRNAs are associated with colorectal cancer (CRC), with alterations depending on the tumor location. Novel tissue-specific miRNAs have been identified in different tumors and are associated with cancer.
Iael Weissberg Minutentag +10 more
doaj +1 more source
miR-590-3p Is a Novel MicroRNA in Myocarditis by Targeting Nuclear Factor Kappa-B in vivo
Cardiology, 2015 <b><i>Objective:</i></b> Nuclear factor kappa-B (NF-κB)-induced inflammation leads to myocarditis and heart dysfunction. How microRNAs (miRNAs) contribute to this process is poorly defined. The aim of this study was to investigate whether miRNAs regulate NF-κB-induced inflammation in experimental autoimmune ...
Xiao-Zhen Zhuo +11 more
openaire +3 more sources
ATF-3/miR-590/GOLPH3 signaling pathway regulates proliferation of breast cancer
BMC Cancer, 2018 Background Breast cancer is one of the leading causes of death in women worldwide. Fast growth is the important character of breast cancer, which makes sure the subsequent metastasize and invasion breast cancer.
Qiong Song +8 more
doaj +1 more source