Results 1 to 10 of about 2,382 (118)

Mir-615-3p promotes osteosarcoma progression via the SESN2/AMPK/mTOR pathway [PDF]

Cancer Cell International
Background Osteosarcoma (OS) is the most common primary malignant bone neoplasm. Growing researches have highlighted the tumor promoting role of miR-615-3p in various cancers.
Xuecheng Yu, Xin Wang, Fan Xu, Xinyi Zhang, Muyi Wang, Ruikai Zhou, Zhengyi Sun, Xiaohui Pan, Lin Feng, Wanchao Zhang, Yong Sun, Wenting Zhang, Dong Zhou, Yuqing Jiang   +13 more
doaj   +4 more sources

miR-615-3p promotes the epithelial-mesenchymal transition and metastasis of breast cancer by targeting PICK1/TGFBRI axis [PDF]

Journal of Experimental & Clinical Cancer Research, 2020
Background Increasing evidence indicates that epithelial-mesenchymal transition (EMT) can be regulated by microRNAs (miRNAs). miR-615-3p was shown to be involved in tumor development.
Bo Lei, Dandan Wang, Ming Zhang, Yuwei Deng, Huijie Jiang, Yiwen Li   +5 more
doaj   +5 more sources

Mmu-miR-615-3p regulates lipoapoptosis by inhibiting C/EBP homologous protein. [PDF]

PLoS ONE, 2014
Lipoapoptosis occurring due to an excess of saturated free fatty acids such as palmitate is a key pathogenic event in the initiation of nonalcoholic fatty liver disease.
Yasuhiro Miyamoto, Amy S Mauer, Swarup Kumar, Justin L Mott, Harmeet Malhi   +4 more
doaj   +6 more sources

The Influence of rs1859168 Polymorphism on Serum Expression of HOTTIP and Its Target miR-615-3p in Egyptian Patients with Breast Cancer [PDF]

Biomolecules, 2021
Background: Polymorphisms of long noncoding RNAs are lately documented as hazardous factors for the development of numerous tumors. Furthermore, the evaluation of noncoding RNAs has emerged as a novel detector of breast cancer patients.
Omayma O. Abdelaleem, Olfat G. Shaker, Marwa N. AbdelHafez, Noha K. Abdelghaffar, Hanaa M. Eid, Mohamed Zaidan, Abeer A. Khalefa, Naglaa A. Ahmed, Nada F. Hemeda, Othman M. Zaki, Aeshah Ali A. Awaji, Shereen R. Mohammed   +11 more
doaj   +5 more sources

Inhibition of miR-615-3p enhances dentinogenesis in scaps via PVT1-mediated mitochondrial regulation [PDF]

Stem Cell Research & Therapy
Background Mesenchymal stem cells (MSCs) are critical for dental tissue regeneration, yet their differentiation potential is tightly regulated by microRNAs (miRNAs).
Haoqing Yang, Yishu Huang, Jiaxin Song, Xiao Han, Fengning Yuan, Zhipeng Fan   +5 more
doaj   +3 more sources

Knockdown of LRP11-AS1 inhibits papillary thyroid tumor growth by modulating miR-615-3p/AKT2 axis [PDF]

Translational Oncology
Patients with papillary thyroid cancer (PTC) who experience local recurrence and distant metastases have a poor clinical prognosis and low survival rate.
Peng Li, Zhongguang Wu, Lanlan Li, Yudan Chen, Chi Zhang, Weidong Zheng   +5 more
doaj   +3 more sources

The glycosyltransferase ST3GAL2 is regulated by miR-615-3p in the intestinal tract of Campylobacter jejuni infected mice [PDF]

Gut Pathogens, 2021
Background Campylobacter jejuni (C. jejuni) infections are of increasing importance worldwide. As a typical mucosal pathogen, the interaction of C. jejuni with mucins is a prominent step in the colonisation of mucosal surfaces. Despite recent advances in
De Xi, Lukas Hofmann, Thomas Alter, Ralf Einspanier, Stefan Bereswill, Markus M. Heimesaat, Greta Gölz, Soroush Sharbati   +7 more
doaj   +7 more sources

Circular RNA circ-MTHFD1L induces HR repair to promote gemcitabine resistance via the miR-615-3p/RPN6 axis in pancreatic ductal adenocarcinoma [PDF]

Journal of Experimental & Clinical Cancer Research, 2022
Background Chemoresistance of pancreatic cancer is the main reason for the poor treatment effect of pancreatic cancer patients. Exploring chemotherapy resistance-related genes has been a difficult and hot topic of oncology. Numerous studies implicate the
Zhi-Wen Chen, Jian-Fei Hu, Zu-Wei Wang, Cheng-Yu Liao, Feng-Ping Kang, Cai-Feng Lin, Yi Huang, Long Huang, Yi-Feng Tian, Shi Chen   +9 more
doaj   +4 more sources

Long noncoding RNA HOTTIP promotes the metastatic potential of ovarian cancer through the regulation of the miR‐615‐3p/SMARCE1 pathway [PDF]

Kaohsiung Journal of Medical Sciences, 2020
Upregulation of lncRNA HOXA transcript at the distal tip (HOTTIP) plays important roles in cancer progression. Nevertheless, its functions in the growth and metastasis of ovarian carcinoma are unknown.
Hong Wu, Hong‐Yan Wei, Qian‐Qian Chen   +2 more
doaj   +5 more sources

Exosomal Transfer of lncRNA H19 Promotes Erlotinib Resistance in Non-Small Cell Lung Cancer via miR-615-3p/ATG7 Axis [PDF]

Cancer Management and Research, 2020
Rongtao Pan,1 Haiyan Zhou2 1Department of Oncology, Taishan Hospital of Shandong Province, Taian 271000, Shandong, People’s Republic of China; 2Department of Medical Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical ...
Pan R, Zhou H
doaj   +6 more sources