Results 111 to 118 of about 2,382 (118)
Some of the next articles are maybe not open access.
Life Sciences, 2020
Bortezomib (BTZ) is described as the first-line agent for multiple myeloma (MM) chemotherapy, but the emergence of BTZ resistance usually results in the failure of chemotherapy in MM. Circular RNA (circRNA) itchy E3 ubiquitin protein ligase (circITCH) is a novel identified circRNA that plays a vital role in the development of human cancers.
Jianhua, Liu +6 more
openaire +2 more sources
Bortezomib (BTZ) is described as the first-line agent for multiple myeloma (MM) chemotherapy, but the emergence of BTZ resistance usually results in the failure of chemotherapy in MM. Circular RNA (circRNA) itchy E3 ubiquitin protein ligase (circITCH) is a novel identified circRNA that plays a vital role in the development of human cancers.
Jianhua, Liu +6 more
openaire +2 more sources
Journal of Proteomics, 2023
Non-small cell lung cancer (NSCLC) is associated with high morbidity and mortality. Propofol functions as a tumor-inhibitor drug by regulating microRNAs (miRNAs). The primary objective of this study is to explore the functional mechanism of propofol in cisplatin (Cis) resistance of NSCLC cells by regulating the miR-744-5p/miR-615-3p axis. Cis-resistant
Bin, Han +3 more
openaire +2 more sources
Non-small cell lung cancer (NSCLC) is associated with high morbidity and mortality. Propofol functions as a tumor-inhibitor drug by regulating microRNAs (miRNAs). The primary objective of this study is to explore the functional mechanism of propofol in cisplatin (Cis) resistance of NSCLC cells by regulating the miR-744-5p/miR-615-3p axis. Cis-resistant
Bin, Han +3 more
openaire +2 more sources
The American Journal of Pathology
In this study, knockout of FOXO3 was found to impair intervertebral disc maturation and homeostasis in postnatal mice as well as facilitating extracellular matrix degradation. RNA sequencing can uncover disease-related gene expression and investigate disease pathophysiology.
Yingjie, Hao +6 more
openaire +2 more sources
In this study, knockout of FOXO3 was found to impair intervertebral disc maturation and homeostasis in postnatal mice as well as facilitating extracellular matrix degradation. RNA sequencing can uncover disease-related gene expression and investigate disease pathophysiology.
Yingjie, Hao +6 more
openaire +2 more sources
Anti-Cancer Agents in Medicinal Chemistry, 2021
Background: Breast Cancer (BC) is the most common malignancy among women with a high mortality rate. The blockade of asparagine-related pathways may be an effective measure to control the progression and reduction of BC metastasis potential. Recently, it has been shown that various miRNAs, as part of small non-coding RNAs, have a great role in cancer ...
Khandan Ilkhani +6 more
openaire +2 more sources
Background: Breast Cancer (BC) is the most common malignancy among women with a high mortality rate. The blockade of asparagine-related pathways may be an effective measure to control the progression and reduction of BC metastasis potential. Recently, it has been shown that various miRNAs, as part of small non-coding RNAs, have a great role in cancer ...
Khandan Ilkhani +6 more
openaire +2 more sources
Cell Biology International, 2017
AbstractOssification of the ligamentum flavum (OLF) is a disease of heterotopic ossification in spinal ligaments. The key of the OLF pathogenesis is the differentiation of fibroblasts into osteoblasts. In this study, we explored the role of miR‐615‐3p in the osteogenic differentiation of human LF cells.
Jichao, Yin +8 more
openaire +2 more sources
AbstractOssification of the ligamentum flavum (OLF) is a disease of heterotopic ossification in spinal ligaments. The key of the OLF pathogenesis is the differentiation of fibroblasts into osteoblasts. In this study, we explored the role of miR‐615‐3p in the osteogenic differentiation of human LF cells.
Jichao, Yin +8 more
openaire +2 more sources
European Journal of Pharmacology, 2019
Increased glycolysis under hypoxic stress is a fundamentally important feature of non-small cell lung cancer (NSCLC) cells, but molecular mechanisms of hypoxia on glycolysis remain elusive. Herein, we aimed to explore whether lncRNAs and miRNAs are involved in the glycolytic reprogramming under hypoxic conditions.
Jiang, Shi +6 more
openaire +2 more sources
Increased glycolysis under hypoxic stress is a fundamentally important feature of non-small cell lung cancer (NSCLC) cells, but molecular mechanisms of hypoxia on glycolysis remain elusive. Herein, we aimed to explore whether lncRNAs and miRNAs are involved in the glycolytic reprogramming under hypoxic conditions.
Jiang, Shi +6 more
openaire +2 more sources
Sa1184 CIRCULAR RNA CIRC-FOXO3 INHIBITS COLORETAL CANCER PROGRESSION VIA THE MIR-615-3P/FOXO3 AXIS
Gastroenterology, 2020Lanping Zhu, Jingwen Zhao, Xin Chen
openaire +1 more source
MicroRNA miR-615-3p and let-7b targets multiple pathways overexpressed in lung adenocarcinoma
2015Kerkentzes, Konstantinos +2 more
openaire +1 more source