Results 31 to 40 of about 2,382 (118)
Cervical cancer (CC) is one of the world’s most common and severe cancers. This cancer includes two histological types: squamous cell carcinoma (SCC) and adenocarcinoma (ADC). The current study aims at identifying novel potential candidate mRNA and miRNA
Parinaz Tabrizi-Nezhadi +5 more
doaj +1 more source
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer. [PDF]
Colorectal cancer (CRC) is one of the leading causes of cancer related deaths and the search for prognostic biomarkers that might improve treatment decisions is warranted.
Kristina Schee +8 more
doaj +1 more source
Elevated miR-615-3p Expression Predicts Adverse Clinical Outcome and Promotes Proliferation and Migration of Prostate Cancer Cells [PDF]
miR-615-3p has previously been described as up-regulated in prostate cancer (PC) tissue samples compared with nonmalignant controls; however, its prognostic potential and functional role in PC remain largely unknown. In this study, we investigated the clinical and biological relevance of miR-615-3p in PC. The expression of miR-615-3p was measured in PC
Emma B. Laursen +14 more
openaire +5 more sources
MicroRNAs Regulate Cellular ATP Levels by Targeting Mitochondrial Energy Metabolism Genes during C2C12 Myoblast Differentiation. [PDF]
In our previous study, we identified an miRNA regulatory network involved in energy metabolism in porcine muscle. To better understand the involvement of miRNAs in cellular ATP production and energy metabolism, here we used C2C12 myoblasts, in which ATP ...
Puntita Siengdee +5 more
doaj +1 more source
CircVAPA promotes proliferation and metastasis of retinoblastoma by modulating miR-615-3p and SMARCE1 [PDF]
Abstract Background Growing evidence reveals that circular RNAs (circRNAs) play roles in cancer development. However, the effects and possible mechanisms of circRNAs in retinoblastoma (RB) are far from clear. Methods circVAPA expression pattern was identified by RT-qPCR.
openaire +1 more source
Identification of key miRNAs in prostate cancer progression based on miRNA-mRNA network construction
Prostate cancer (PC) is one of the major male cancers. Differential diagnosis of PC is indispensable for the individual therapy, i.e., Gleason score (GS) that describes the grade of cancer can be used to choose the appropriate therapy.
Giulia Dal Santo +4 more
doaj +1 more source
Identifying target microRNAs (miRNAs) might serve as a basis for developing advanced therapies for Parkinson’s disease (PD) and Alzheimer’s disease. This review aims to identify the main therapeutic targets of miRNAs that can potentially act in Parkinson’
Idiberto José Zotarelli-Filho +11 more
doaj +1 more source
Background Prostate cancer is one of the most common and socially significant cancers among men. The aim of our study was to reveal changes in miRNA expression profiles associated with lymphatic dissemination in prostate cancer and to identify the most ...
Elena A. Pudova +18 more
doaj +1 more source
Background As the fetal heart develops, cardiomyocyte proliferation potential decreases while fatty acid oxidative capacity increases in a highly regulated transition known as cardiac maturation.
Adar Aharon-Yariv +3 more
doaj +1 more source
Graves ophthalmopathy (GO), a manifestation of Graves’ disease, is an organ-specific autoimmune disease. Intravenous glucocorticoid therapy (ivGCs) is the first-line treatment for moderate-to-severe and active GO.
Jingxue Sun +8 more
doaj +1 more source

