Results 71 to 80 of about 2,382 (118)

Additional file 7 of Circular RNA circ-MTHFD1L induces HR repair to promote gemcitabine resistance via the miR-615-3p/RPN6 axis in pancreatic ductal adenocarcinoma

, 2022
Additional file 7: Table S2.
Chen, Zhi-Wen, Hu, Jian-Fei, Wang, Zu-Wei, Liao, Cheng-Yu, Kang, Feng-Ping, Lin, Cai-Feng, Huang, Yi, Huang, Long, Tian, Yi-Feng, Chen, Shi   +9 more
openaire   +1 more source

Uterine Extracellular Vesicles Can Emulate the Long‐Term Effects of Post‐Partum Negative Energy Balance in Dairy Cows

Molecular Reproduction and Development, Volume 92, Issue 10, October 2025.
ABSTRACT Dairy cows often experience a period of negative energy balance (NEB) during the post‐calving period, which can significantly impact economic outcomes due to extended calving‐to‐conception intervals and overall reduced fertility. This reduction is due, in part, to the impact on uterine biology by high nonesterified fatty acids (NEFA) and beta ...
Juliana Germano Ferst, Matheus Andrade Chaves, Amanda Nespolo Silva, Schaienni Fontoura Saldanha, Rogério Ferreira, Ricardo Perecin Nociti, Angélica Camargo dos Santos, Samuel Volpe Souza, Marcos Roberto Chiaratti, Guilherme Pugliesi, Felipe Perecin, Flávio Vieira Meirelles, Juliano Coelho da Silveira   +12 more
wiley   +1 more source

Exploring MicroRNA Biomarkers for Parkinson’s Disease from mRNA Expression Profiles

Cells, 2018
Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disease characterized by both motor and nonmotor features. The diagnose of PD is based on a review of patients’ signs and symptoms, and neurological and physical ...
Y-h. Taguchi, Hsiuying Wang
doaj   +1 more source

Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications

MedComm, Volume 6, Issue 9, September 2025.
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen, Jiachen Liu, Yinhuai Wang, Zebin Deng, Fei Deng   +4 more
wiley   +1 more source

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

Med Research, Volume 1, Issue 2, Page 207-225, September 2025.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang, Yanyun Pang, Peijia Zhu, Zhengdong Zhang, Sen Guo, Zhijian Wei, Wenzhao Wang, Bin Ning   +7 more
wiley   +1 more source

Exosomes in Metabolic Diseases: From Molecular Mechanisms to Clinical Applications

MedComm – Future Medicine, Volume 4, Issue 3, September 2025.
We summarize recent progress in exosome biology and elucidate their roles in interorgan communication networks underlying metabolic pathogenesis. We also comprehensively examine the evolving application of exosomes in metabolic disease management, with a focus on critically evaluating preclinical and clinical advances in exosome‐mediated therapeutic ...
Yanting Wu, Shanshan Yang, You Zhang, Zhiguang Su   +3 more
wiley   +1 more source

Circular RNA 100146 functions as an oncogene through direct binding to miR-361-3p and miR-615-5p in non-small cell lung cancer

Molecular Cancer, 2019
Circular RNAs are widely expressed in eukaryotic cells and associated with cancer. However, limited studies to date have focused on the potential role of circRNAs in progression of lung cancer.
Lijian Chen, Aruo Nan, Nan Zhang, Yangyang Jia, Xin Li, Yihui Ling, Jiabin Dai, Shaozhu Zhang, Qiaoyuan Yang, Yanni Yi, Yiguo Jiang   +10 more
doaj   +1 more source

Entamoeba histolytica Up-Regulates MicroRNA-643 to Promote Apoptosis by Targeting XIAP in Human Epithelial Colon Cells

Frontiers in Cellular and Infection Microbiology, 2019
MicroRNAs (miRNAs) are small non-coding RNAs that function as negative regulators of gene expression. Recent evidences suggested that host cells miRNAs are involved in the progression of infectious diseases, but its role in amoebiasis remains largely ...
Itzel López-Rosas, César López-Camarillo, Yarely M. Salinas-Vera, Olga N. Hernández-de la Cruz, Carlos Palma-Flores, Bibiana Chávez-Munguía, Osbaldo Resendis-Antonio, Nancy Guillen, Carlos Pérez-Plasencia, Carlos Pérez-Plasencia, María Elizbeth Álvarez-Sánchez, Esther Ramírez-Moreno, Laurence A. Marchat   +12 more
doaj   +1 more source

Identification of Prognostic Biomarker Signatures and Candidate Drugs in Colorectal Cancer: Insights from Systems Biology Analysis

Medicina, 2019
Colorectal cancer (CRC) is the second most common cause of cancer-related death in the world, but early diagnosis ameliorates the survival of CRC. This report aimed to identify molecular biomarker signatures in CRC.
Md. Rezanur Rahman, Tania Islam, Esra Gov, Beste Turanli, Gizem Gulfidan, Md. Shahjaman, Nilufa Akhter Banu, Md. Nurul Haque Mollah, Kazim Yalcin Arga, Mohammad Ali Moni   +9 more
doaj   +1 more source

Lipid metabolism-related genes are involved in the occurrence of asthma and regulate the immune microenvironment

BMC Genomics
Background Lipid metabolism plays a pivotal role in asthma pathogenesis. However, a comprehensive analysis of the importance of lipid metabolism-related genes (LMRGs) in regulating the immune microenvironment in asthma remains lacking.
Yuanmin Jia, Haixia Wang, Bin Ma, Zeyi Zhang, Jingjing Wang, Jin Wang, Ou Chen   +6 more
doaj   +1 more source