Hsa_circRNA_100146 Promotes Prostate Cancer Progression by Upregulating TRIP13 via Sponging miR-615-5p [PDF]
Frontiers in Molecular Biosciences, 2021 Objective: This study was conducted for investigating the functions of circular RNA circRNA_100146 (circRNA_100146) in the development of prostate cancer (PCa) and identifying the underlying mechanisms of the circRNA_100146/miR-615-5p/TRIP13 axis ...
Liang Zeng +4 more
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Mir-615-5p inhibits cervical cancer progression by targeting TMIGD2 [PDF]
HereditasBackground Cervical cancer (CC) is a prevalent gynecological malignancy, contributing to a substantial number of fatalities among women. MicroRNAs (miRNAs) have emerged as promising biomarkers with significant potential for the early detection and ...
Yan Zhao +6 more
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Hydroxyacid Oxidase 2 (HAO2) Inhibits the Tumorigenicity of Hepatocellular Carcinoma and Is Negatively Regulated by miR-615-5p [PDF]
Journal of Immunology Research, 2022 Background. Hepatocellular carcinoma (HCC) is the sixth most common kind of cancer worldwide and the third leading cause of cancer mortality. Although a few studies have shown that hydroxyacid oxidase 2 (HAO2) may prevent HCC development, the molecular ...
Yuxuan Li +9 more
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Y-box protein-1 modulates circSPECC1 to promote glioma tumorigenesis via miR-615-5p/HIP1/AKT axis [PDF]
Acta Biochimica et Biophysica Sinica, 2023 Y-box binding protein-1 (YB-1) is upregulated in glioma and plays an important role in its occurrence and drug resistance. However, the involved regulatory processes and downstream pathways are still unclear. Since
Lan Ping +9 more
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circ_0006789 promotes cervical cancer development via the miR-615-5p/HSF1 axis [PDF]
Discover OncologyObjective Circular RNAs (circRNAs) are involved in the development of human cancers, including cervical cancer (CC). However, the role and mechanism of circ_0006789 (circSLC25A43) in CC are unclear.
Wenyu Zhou, Weiwei Song, Meisong Lu
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Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis [PDF]
Journal of NeuroinflammationDemyelination and failure of remyelination in the central nervous system (CNS) characterize a number of neurological disorders. Spontaneous remyelination in demyelinating diseases is limited, as oligodendrocyte precursor cells (OPCs), which are often ...
Xiao-Yu Ji +14 more
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RETRACTED ARTICLE: The novel circular RNA circ-CAMK2A enhances lung adenocarcinoma metastasis by regulating the miR-615-5p/fibronectin 1 pathway [PDF]
Cellular & Molecular Biology Letters, 2019 Background Circular RNA (circRNA) has recently been considered as a key regulator in carcinogenesis. In this study, we investigated the functional significance and regulatory role of circ-CAMK2A (hsa_circ_0128332) in lung adenocarcinoma (LUAD).
Jiahui Du +4 more
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CircRNA circ-OGDH (hsa_circ_0003340) Acts as a ceRNA to Regulate Glutamine Metabolism and Esophageal Squamous Cell Carcinoma Progression by the miR-615-5p/PDX1 Axis [PDF]
Cancer Management and Research, 2021 Zongying Liang, Baoshan Zhao, Jishen Hou, Jingxiong Zheng, Guohua Xin Department of Thoracic Surgery, The Affiliated Hospital of Chengde Medical University, Chengde, 067000, People’s Republic of ChinaCorrespondence: Guohua XinDepartment of Thoracic
Liang Z, Zhao B, Hou J, Zheng J, Xin G
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Circ-CDK8 regulates SLC7A11-mediated ferroptosis by inhibiting miR-615-5p to promote progression in oral squamous cell carcinomas [PDF]
Frontiers in PharmacologyIntroduction: Ferroptosis is a new mode of programmed cell death distinct from necrosis, apoptosis, and autophagy, induced by iron-ion-dependent lipid peroxide accumulation.
Kai Sun +19 more
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Hsa_circ_0023179 modulated the processes of proliferation, apoptosis, and EMT in non-small cell lung cancer cells via the miR-615-5p/CDH3 axis [PDF]
Biomolecules & BiomedicineCircular RNA (circRNA) has been widely studied as a competitive endogenous RNA targeting microRNA (miRNA)/messenger RNA to regulate cancer progression.
Qingkui Guo, Min Zheng, Chen Zhu, Bin Wu
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