Results 31 to 40 of about 2,436 (103)
Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer. [PDF]
PLoS ONE, 2013 Colorectal cancer (CRC) is one of the leading causes of cancer related deaths and the search for prognostic biomarkers that might improve treatment decisions is warranted.
Kristina Schee +8 more
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Journal of Advanced Research, 2020 Circulatory microRNAs have recently emerged as non-invasive and effective biomarkers for diagnosis of various diseases. Currently there is no reliable biomarker for diagnosis, prognosis or even staging of fibrotic and cirrhotic complications arising from
Shohda A. El-Maraghy +5 more
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European review for medical and pharmacological sciences, 2018 The underlying mechanism of long non-coding RNA (lncRNA) in lung adenocarcinoma (LAC) has not been fully understood yet. Hence, this study aimed to determine the biological function of LINC00324 in LAC and to provide a novel diagnostic and therapeutic target for it.The expression level of LINC00324 in 87 paired LAC tumor tissues and matched para-tumor ...
Pan, Z.-H. +3 more
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PU.1 Is Identified as a Novel Metastasis Suppressor in Hepatocellular Carcinoma Regulating the miR-615-5p/IGF2 Axis [PDF]
Asian Pacific Journal of Cancer Prevention, 2015 Invasion and metastasis is the major cause of tumor recurrence, difficulty for cure and low survival rate. Excavating key transcription factors, which can regulate tumor invasion and metastasis, are crucial to the development of therapeutic strategies for cancers. PU.1 is a master hematopoietic transcription factor and a vital regulator in life.
Li-Jie, Song +6 more
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miR‐615‐5p is restrictedly expressed in cirrhotic and cancerous liver tissues and its overexpression alleviates the tumorigenic effects in hepatocellular carcinoma [PDF]
FEBS Letters, 2012 microRNAs aberrant behavior in heptocellular carcinoma (HCC) plays a major role in HCC pathogenesis. miR‐615‐5p expression has never been evaluated in HCC. We showed that miR‐615‐5p was preferentially expressed in HCC, cirrhotic liver tissues and HCC cell lines, but undetected in normal livers.
El Tayebi, H.M. +4 more
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MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.
PLoS Genetics, 2014 Transcriptional dysregulation has long been recognized as central to the pathogenesis of Huntington's disease (HD). MicroRNAs (miRNAs) represent a major system of post-transcriptional regulation, by either preventing translational initiation or by ...
Andrew G Hoss +11 more
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Potential mechanism of circRNA_000585 in cholangiocarcinoma
Journal of International Medical Research, 2021 Objective Circular RNA (circRNA) plays a vital role in the development and progression of malignancies, however, the function of circRNAs in cholangiocarcinoma (CCA) remains unexplored.
Fengming Yi, Longxiang Xin, Long Feng
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Biomedicines, 2023 Identifying target microRNAs (miRNAs) might serve as a basis for developing advanced therapies for Parkinson’s disease (PD) and Alzheimer’s disease. This review aims to identify the main therapeutic targets of miRNAs that can potentially act in Parkinson’
Idiberto José Zotarelli-Filho +11 more
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BMC Medical Genomics, 2020 Background Prostate cancer is one of the most common and socially significant cancers among men. The aim of our study was to reveal changes in miRNA expression profiles associated with lymphatic dissemination in prostate cancer and to identify the most ...
Elena A. Pudova +18 more
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Urinary MicroRNAs of Prostate Cancer: Virus-Encoded hsv1-miRH18 and hsv2-miR-H9-5p Could Be Valuable Diagnostic Markers [PDF]
International Neurourology Journal, 2015 Purpose: MicroRNAs (miRNAs) in biological fluids are potential biomarkers for the diagnosis and assessment of urological diseases such as benign prostatic hyperplasia (BPH) and prostate cancer (PCa).
Seok Joong Yun +19 more
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