Results 51 to 60 of about 2,436 (103)

Expression Profiles of Circular RNA in Aortic Vascular Tissues of Spontaneously Hypertensive Rats

open access: yesFrontiers in Cardiovascular Medicine, 2021
Background: Circular RNAs (circRNAs), as a kind of endogenous non-coding RNA, have been implicated in ischemic heart diseases and vascular diseases.
Ying Liu   +27 more
doaj   +1 more source

Entamoeba histolytica Up-Regulates MicroRNA-643 to Promote Apoptosis by Targeting XIAP in Human Epithelial Colon Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
MicroRNAs (miRNAs) are small non-coding RNAs that function as negative regulators of gene expression. Recent evidences suggested that host cells miRNAs are involved in the progression of infectious diseases, but its role in amoebiasis remains largely ...
Itzel López-Rosas   +12 more
doaj   +1 more source

Three novel circRNAs upregulated in tissue and plasma from hepatocellular carcinoma patients and their regulatory network

open access: yesCancer Cell International, 2021
Background The regulatory roles of circular RNAs (circRNAs) in tumorigenesis have attracted increasing attention. However, novel circRNAs with the potential to be used as serum/plasma biomarkers and their regulatory mechanism in the pathogenesis of ...
Lianghai Wang   +6 more
doaj   +1 more source

An Injectable Epigenetic Autophagic Modulatory Hydrogel for Boosting Umbilical Cord Blood NK Cell Therapy Prevents Postsurgical Relapse of Triple‐Negative Breast Cancer

open access: yesAdvanced Science, 2022
Triple‐negative breast cancer (TNBC) exhibits resistance to conventional treatments due to the presence of cancer stem cells (CSCs), causing postsurgical relapse and a dismal prognosis.
Yihang Gong   +12 more
doaj   +1 more source

LncRNA Gm15290 Promotes Cell Proliferation and Invasion in Non-Small Cell Lung Cancer Through Directly Interacting With and Suppressing the Tumor Suppressor miR-615-5p

open access: yesOncology Research Featuring Preclinical and Clinical Cancer Therapeutics, 2017
Long non-coding RNAs (lncRNAs) have been involved in occurrence and progression of multiple cancers. In this study, weinvestigated the role of lncRNA Gm15290 in the proliferation and invasion of non-small cell lung cancer (NSCLC) cells. First, we found that lncRNA Gm15290 was markedly upregulated in tumor tissues from NSCLC patients and NSCLC cell ...
Yu, Dong   +5 more
openaire   +2 more sources

Exploring MicroRNA Biomarkers for Parkinson’s Disease from mRNA Expression Profiles

open access: yesCells, 2018
Parkinson’s disease (PD) is a chronic, progressive neurodegenerative disease characterized by both motor and nonmotor features. The diagnose of PD is based on a review of patients’ signs and symptoms, and neurological and physical ...
Y-h. Taguchi, Hsiuying Wang
doaj   +1 more source

MOESM1 of The novel circular RNA circ-CAMK2A enhances lung adenocarcinoma metastasis by regulating the miR-615-5p/fibronectin 1 pathway

open access: yes, 2019
Additional file 1 :Figure S1. Northern blot analysis of circ-CAMK2A expression in three pairs of LUAD and normal tissues. 18S was used as control reference. Figure S2. qRT-PCR analysis of CAMK2A expression in LUAD cells with circ-CAMK2A overexpression or knockdown. Figure S3.
Jiahui Du   +4 more
openaire   +1 more source

Amniotic fluid‐derived small extracellular vesicles for predicting postnatal severe outcome of congenital diaphragmatic hernia

open access: yesJournal of Extracellular Biology
Congenital diaphragmatic hernia (CDH) is a life‐threatening condition with high morbidity and mortality rates. The survival rate of neonates with severe CDH is reportedly only 10%–15%.
Seiko Matsuo   +11 more
doaj   +1 more source

Additional file 4: of Circular RNA 100146 functions as an oncogene through direct binding to miR-361-3p and miR-615-5p in non-small cell lung cancer

open access: yes, 2019
Figure S1. Identification of circRNA 100146 and its expression in lung cancer tissues. Figure S2. Suppression of circRNA 100146 expresssion inhibits cancer cell invasion and migration in vitro. Figure S3. circRNA 100146 binds subtypes of splicing factor SF3 family. Figure S4.
Lijian Chen   +10 more
openaire   +1 more source

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