Results 101 to 110 of about 214,976 (242)
Tomb of Mir Mahmud Nimatullahi
, 2007 Located on a hillock on Mir Alam road west of Charminar is the tomb-dargah of Mir Mahmud Nimatullah, who came from Najaf in the reign of Abdullah Qutb Shah 1626-72. Mir Mahmud Nimatullah passed away in 1688. A flight of 101 steps lead to the four massive
Mir Alam
core
miR-105 and miR-767 expression across cell lines.
, 2022 (A) miR-105 and (B) miR-767 expression levels were measured across 13 cell lines. (C) Expression was consistent with patient data, as miR-105 and miR-767 expression were highly correlated.
Guanying Bianca Xu (12700306) +3 more
core +1 more source
Advanced Functional Materials, EarlyView.We present a novel proteolysis‐targeting chimera (PROTAC) system conjugated to lipoic acid gold nanoclusters (PLANC), designed to degrade pTau, regulate inflammatory signaling, and effectively traverse the blood‐brain barrier (BBB). PLANC degraded pTau at various phosphorylation sites, with mechanistic studies confirming proteasome‐mediated degradation
Sarah Nevins +9 more
wiley +1 more source
Supplementary Figures 1-6 from miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell Death
, 2023 Supplementary Figures 1-6 from miR-181a and miR-630 Regulate Cisplatin-Induced Cancer Cell ...
Guido Kroemer +15 more
openaire +1 more source
Hierarchical MXene‐Derived NTP/C Nanohybrids for Cryogenic Sodium‐Ion Batteries
Advanced Functional Materials, EarlyView.A hierarchical MXene‐derived NaTi2(PO4)3/C nanohybrid enables efficient sodium‐ion storage down to −40°C by integrating fast ion–electron transport pathways with an ether‐based electrolyte. The system promotes dominant pseudocapacitive behavior and forms a robust inorganic‐rich SEI, collectively mitigating kinetic and interfacial limitations, thereby ...
M. Sai Bhargava Reddy +5 more
wiley +1 more source
miRNA-21和miRNA-134在乳腺癌患者血清中表达情况及其临床意义
Zhongshan Daxue xuebao. Yixue kexue ban, 2016 [目的] 研究乳腺癌相关miRNA在正常人群及乳腺癌患者血清中的表达情况，统计分析其在乳腺癌诊断中的临床价值。[方法] 收集47例乳腺癌及50例正常体检人群血清，通过实时荧光定量PCR（RT-PCR）检测各组miR-630、miR-21、miR-195、miR-134 、miR-200a、miR-381、miR-1228的表达情况。分析单个血清miRNA在乳腺癌诊断中的价值，进一步用统计学方法分析多个miRNA联合检测的诊断价值。[结果]相比正常体检人群，乳腺癌患者血清中miR134和miR21表达增加，
石岩
doaj
Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels
Advanced Healthcare Materials, EarlyView.We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa +8 more
wiley +1 more source
, 2016 (A) Quantification of pri-miR-590 by qRT-PCR normalized by GAPDH. Mean ± SD (n = 3). HEK293T cells were transfected with the pri-miR-590-WT or pri-miR-590-SNP plasmids. The empty plasmid was used as negative control.
Suresh K. Kandasamy (2794198) +15 more
core +1 more source
Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway [PDF]
, 2015 Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens.
Drakaki, A +23 more
core +1 more source
Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells
Advanced Materials, EarlyView.This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno +16 more
wiley +1 more source