Results 111 to 120 of about 6,232 (244)

Over-expression of the miR-483-3p overcomes the miR-145/TP53 pro-apoptotic loop in hepatocellular carcinoma [PDF]

open access: yes, 2016
The miR-145-5p, which induces TP53-dependent apoptosis, is down-regulated in several tumors, including hepatocellular carcinomas (HCCs), but some HCCs show physiological expression of this miR.
Bolondi, Luigi   +18 more
core   +5 more sources

Tin‐Oxo Nanocluster Extreme UV Photoresists Equipped with Chemical Features for Atmospheric Stability and High EUV Sensitivity

open access: yesAdvanced Functional Materials, EarlyView.
Fluoroalkyl‐functionalized tin–oxo nanoclusters (N‐TOC6) enable robust pattern formation through ligand crosslinking under EUV exposure without thermal processing. Sn–F coordination mitigates the Lewis acidity of Sn centers, suppressing reactions with airborne molecules and improving post‐exposure pattern stability.
Yejin Ku   +18 more
wiley   +1 more source

Lower miR-630 expression predicts poor prognosis of osteosarcoma and promotes cell proliferation, migration and invasion by targeting PSMC2.

open access: yesEuropean review for medical and pharmacological sciences, 2019
miR-630 has been reported as a tumor suppressor or tumor promoter in various types of cancer. However, the effect of miR-630 in osteosarcoma (OS) has not been investigated. The purpose of this study was to investigate the expression patterns, clinical value, and functional role of miR-630 in OS.miR-630 levels in 147 paired OS tissues and corresponding ...
Li, G.-W., Yan, X.
openaire   +2 more sources

High Entropy Wide‐Bandgap Borates with Broadband Luminescence and Large Nonlinear Optical properties

open access: yesAdvanced Functional Materials, EarlyView.
High‐entropy rare‐earth borates exhibit excellent nonlinear optical and broadband luminescence properties arising from multi‐component doping, chemical disorder, increased configurational entropy, and increased lattice and electronic anharmonicity. This formulation enabled us to obtain a large, environmentally stable single crystal with 3X higher laser‐
Saugata Sarker   +14 more
wiley   +1 more source

Bioinspired Stabilization of Fluorescent Au@SiO2 Tracers for Multimodal Biological Imaging

open access: yesAdvanced Functional Materials, EarlyView.
This study demonstrates a bioinspired stabilization strategy for fluorescent gold‐silica nanoparticles. Inspired by natural biosilica maturation, high‐temperature calcination transforms the silica shells, preventing dissolution in cell culture media and intracellular environments.
Wang Sik Lee   +5 more
wiley   +1 more source

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

miRNA-21和miRNA-134在乳腺癌患者血清中表达情况及其临床意义

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2016
[目的] 研究乳腺癌相关miRNA在正常人群及乳腺癌患者血清中的表达情况,统计分析其在乳腺癌诊断中的临床价值。[方法] 收集47例乳腺癌及50例正常体检人群血清,通过实时荧光定量PCR(RT-PCR)检测各组miR-630、miR-21、miR-195、miR-134 、miR-200a、miR-381、miR-1228的表达情况。分析单个血清miRNA在乳腺癌诊断中的价值,进一步用统计学方法分析多个miRNA联合检测的诊断价值。[结果]相比正常体检人群,乳腺癌患者血清中miR134和miR21表达增加,
石岩
doaj  

Hsa_circ_0079474 facilitates epithelial-mesenchymal transition in intrauterine adhesion via miR-630/YAP1 axis

open access: yes
Abstract Insufficient understanding exists of the molecular mechanisms underlying circRNA involvement in IUA and requires further investigation. This research aims to examine the role of hsa_circ_0079474 (circDGKB-009) and its potential mechanisms in intrauterine adhesion (IUA).
Chen Xing   +23 more
openaire   +1 more source

Laser Engineering of HfN‐Based Nanoparticles for Safe NIR‐I Photothermal and X‐ray Enhancing Cancer Therapies

open access: yesAdvanced Functional Materials, EarlyView.
In this study, we produced HfN‐based nanoparticles via femtosecond laser ablation in acetone. The nanoparticles exhibit a red‐shifted plasmonic resonance in the NIR‐I window, colloidal stability after coating with polyethyleneglycol, and excellent biocompatibility. The photothermal and X‐ray sensitization therapeutic effects were demonstrated for tumor
Julia S. Babkova   +15 more
wiley   +1 more source

MicroRNAs como nueva herramienta diagnóstica en DLBCL [PDF]

open access: yes, 2018
[ES] El linfoma difuso de células B grandes, también conocido por sus siglas en inglés como DLBCL (Diffuse large B-cell lymphoma), es uno de los más de 50 tipos diferentes de linfomas descritos por la Organización Mundial de
Martínez de la Puente Molina, Eduardo
core  

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