Results 41 to 50 of about 3,028 (210)

Plasma miR-940 may serve as a novel biomarker for gastric cancer

Tumor Biology, 2015
It was reported that circulating microRNAs could be applied as non-invasive biomarkers for cancer monitoring. The purpose of this study was to identify plasma miRNA that may serve as a novel biomarker for gastric cancer and to evaluate its clinical application.
Chu, KM, Kwong, A, Liu, X, Sihoe, DLA
openaire   +4 more sources

Hsa-miR-557 Inhibits Osteosarcoma Growth Through Targeting KRAS

Frontiers in Genetics, 2022
Objective: Osteosarcoma is the most common malignancy in the skeletal system; studies showed an important role of miRNAs in tumorigenesis, indicating miRNAs as possible therapeutic molecules.
Zhi Qiao, Jinfeng Li, Hongwei Kou, Xiangrong Chen, Deming Bao, Guowei Shang, Songfeng Chen, Yanhui Ji, Tian Cheng, Yisheng Wang, Hongjian Liu   +10 more
doaj   +1 more source

hsa_circ_0038382 upregulates T-box transcription factor 5 to inhibit keloid formation by interacting with miR-940

Advances in Clinical and Experimental Medicine, 2022
A keloid is a benign fibroproliferative skin tumor whose formation is regulated by circular RNAs (circRNAs). However, the effect and regulatory mechanism of hsa_circ_0038382 on keloid formation have not been investigated.This study aimed to identify the function and mechanism of hsa_circ_0038382 in keloid formation.The expression levels of ...
Meihong, Cai, Zhen, Hu, Lin, Liu, Jiangwei, Su   +3 more
openaire   +2 more sources

MicroRNA-1202 plays a vital role in osteoarthritis via KCNQ1OT1 has-miR-1202-ETS1 regulatory pathway

Journal of Orthopaedic Surgery and Research, 2020
Background This study aimed to explore the molecular mechanism of osteoarthritis (OA) and provide information about new genes as potential targets for OA treatment.
Changzeng Liu, Jianming Gao, Guangyan Su, Yang Xiang, Le Wan   +4 more
doaj   +1 more source

Development of a Novel Immune Infiltration-Related ceRNA Network and Prognostic Model for Sarcoma

Frontiers in Cell and Developmental Biology, 2021
Due to the rarity and heterogeneity, it is challenging to explore and develop new therapeutic targets for patients with sarcoma. Recently, immune cell infiltration in the tumor microenvironment (TME) was widely studied, which provided a novel potential ...
Deyao Shi, Deyao Shi, Shidai Mu, Feifei Pu, Binlong Zhong, Binwu Hu, Jianxiang Liu, Tongchuan He, Zhicai Zhang, Zengwu Shao   +9 more
doaj   +1 more source

MiR-940 regulates angiogenesis after cerebral infarction through VEGF.

European review for medical and pharmacological sciences, 2018
The aim of this study was to investigate whether miR-490 was involved in the regulation of angiogenesis after cerebral infarction by regulating vascular endothelial growth factor (VEGF) expression.Sprague Dawley (SD) rats were used to establish a middle cerebral artery infarction model.
Liu, D., Tang, Z.-Y., Hu, Z.-J., Li, W.-W., Yuan, W.-N.   +4 more
openaire   +2 more sources

Hypoxia- and Inflammation-Related Transcription Factor SP3 May Be Involved in Platelet Activation and Inflammation in Intracranial Hemorrhage

Frontiers in Neurology, 2022
The purpose of this study was to identify the biomarkers implicated in the development of intracranial hemorrhage (ICH) and potential regulatory pathways.
Ding Wan, Ding Wan, Jin Feng, Peng Wang, Zhenxing Yang, Tao Sun, Tao Sun   +6 more
doaj   +1 more source

Circulating microRNAs in Response to Exercise Training in Healthy Adults

Frontiers in Genetics, 2020
Circulating microRNAs (miRNAs, miRs) have great potential as cardiac biomarkers and they are also being explored for their roles in intercellular communication and gene expression regulation.
Qiulian Zhou, Qiulian Zhou, Chao Shi, Yicheng Lv, Chenglin Zhao, Zheng Jiao, Tianhui Wang   +6 more
doaj   +1 more source

Long non-coding RNA LINC01559 serves as a competing endogenous RNA accelerating triple-negative breast cancer progression

Biomedical Journal, 2022
Background: Long non-coding RNA (lncRNA) is an endogenous RNA over 200 nt in length involved in gene regulation. LINC01559 is a novel lncRNA that has been identified as a fundamental player in human cancer.
Xue Yang, Yunqing Yang, Xueke Qian, Xiaodong Xu, Pengwei Lv   +4 more
doaj   +1 more source

Non-destructive Evaluation of the Quality Characteristics of Pomegranate Kernel Oil by Fourier Transform Near-Infrared and Mid-Infrared Spectroscopy

Frontiers in Plant Science, 2022
The pomegranate kernel oil has gained global awareness due to the health benefits associated with its consumption; these benefits have been attributed to its unique fatty acid composition.
Emmanuel E. Okere, Emmanuel E. Okere, Ebrahiema Arendse, Helene Nieuwoudt, Willem J. Perold, Umezuruike Linus Opara, Umezuruike Linus Opara   +6 more
doaj   +1 more source