Journal of Experimental & Clinical Cancer Research, 2021 Background A prostate cancer diagnosis is based on biopsy sampling that is an invasive, expensive procedure, and doesn’t accurately represent multifocal disease.
Simona Giglio +10 more
doaj +1 more source
Journal of Orthopaedic Surgery and Research, 2021 Background Osteoarthritis (OA) is a chronic degenerative joint disease and the most frequent type of arthritis. This study aimed to identify the key miRNAs and genes associated with OA progression.
Pei-yan Huang +6 more
doaj +1 more source
A Concise Review on Dysregulation of LINC00665 in Cancers
Cells, 2022 Long Intergenic Non-Protein Coding RNA 665 (LINC00665) is an RNA gene located on the minus strand of chromosome 19. This lncRNA acts as a competing endogenous RNA for miR-4458, miR-379-5p, miR-551b-5p, miR-3619-5p, miR-424-5p, miR-9-5p, miR-214-3p, miR ...
Soudeh Ghafouri-Fard +5 more
doaj +1 more source
Microcystin-leucine arginine causes cytotoxic effects in sertoli cells resulting in reproductive dysfunction in male mice [PDF]
, 2016 2016-2017 > Academic research: refereed > Publication in refereed journal201804_a bcmaVersion of ...
Chen, YB +6 more
core +1 more source
Preliminary evidence supports circulating microRNAs as prognostic biomarkers for type 2 diabetes. [PDF]
, 2017 Background:Circulating microRNAs are emerging as potential prognostic biomarkers for the development of type 2 diabetes. However, microRNAs are also associated with complications from impaired glucose metabolism (e.g. endothelial cell function).
Allen, IE +5 more
core +1 more source
A blood microRNA classifier for the prediction of ICU mortality in COVID-19 patients: a multicenter validation study [PDF]
, 2023 Background: The identification of critically ill COVID-19 patients at risk of fatal outcomes remains a challenge. Here, we first validated candidate microRNAs (miRNAs) as biomarkers for clinical decision-making in critically ill patients.
Añón, José M. +45 more
core +5 more sources
Frontiers in Cell and Developmental Biology, 2021 Being located on 17q25.1, small nucleolar RNA host gene 6 (SNHG16) is a member of SNHG family of long non-coding RNAs (lncRNA) with 4 exons and 13 splice variants.
Soudeh Ghafouri-Fard +3 more
doaj +1 more source
LncRNA HEIH Confers Cell Sorafenib Resistance in Hepatocellular Carcinoma by Regulating miR-98-5p/PI3K/AKT Pathway. [PDF]
Cancer Manag Res, 2020 The hepatocellular carcinoma up-regulated EZH2-associated long non-coding RNA (HEIH) has been identified to act as an oncogene to promote cell tumorigenesis in hepatocellular carcinoma (HCC); however, the roles of HEIH in sorafenib resistance in HCC cells remain elusive.The expression of HEIH and microRNA (miR)-98-5p was detected using quantitative ...
Shen Q +5 more
europepmc +4 more sources
LncRNA HOXA11-AS promotes OSCC progression by sponging miR-98-5p to upregulate YBX2 expression
Biomedicine & Pharmacotherapy, 2020 Oral squamous cell carcinoma (OSCC) is a type of oral malignancy. Long non-coding RNAs (lncRNAs) have been shown to be related to the occurrence and development of many cancers. Here, we aimed to study the role and molecular mechanism of lncRNA Homeobox A11 antisense RNA (HOXA11-AS) in OSCC.The expression levels of HOXA11-AS, miR-98-5p and Y box ...
Xingyu, Niu +3 more
openaire +2 more sources
The BACH1/Nrf2 Axis in Brain in Down Syndrome and Transition to Alzheimer Disease-Like Neuropathology and Dementia [PDF]
, 2020 Down syndrome (DS) is the most common genetic cause of intellectual disability that is associated with an increased risk to develop early-onset Alzheimer-like dementia (AD).
Barone, Eugenio +4 more
core +4 more sources