PITPNA-AS1/miR-98-5p to Mediate the Cisplatin Resistance of Gastric Cancer. [PDF]
J Oncol, 2022 Gastric cancer (GC) is the most deadly gastrointestinal malignancy with high incidence and mortality. Although, molecular mechanisms which drive gastric cancer progression are extensively investigated, the roles of long noncoding RNA (lncRNA) in gastric cancer growth and drug sensitivity remain unclear.
Ma Z +7 more
europepmc +3 more sources
LncRNA HEIH regulates proliferation and apoptosis of lung cancer cells through miR-98-5p [PDF]
Jichu yixue yu linchuang, 2020 Objective To investigate the effect of lncRNA HEIH on proliferation and apoptosis of lung cancer cells and its mechanism. Methods Human lung epithelial cells BEAS-2B and lung cancer cell lines A549, A427, H1299 and TKB-1 were cultured, and the expression
JIANG Qing-feng, YU Yong-kui, CHENG Jin-hua, SHEN Si-ning, XING Wen-qun
doaj +1 more source
ImmunobiologyBackground: Studies have shown that serum microRNA detection holds significant potential in improving the diagnostic accuracy of mycoplasma pneumoniae pneumonia (MPP).
Ying Li +3 more
doaj +3 more sources
LncRNA NEAT1 promotes glioma cancer progression via regulation of miR-98-5p/BZW1. [PDF]
Biosci Rep, 2021 AbstractBackground: Glioma is the most common malignant tumor in the human central nervous system. Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) promotes oncogenesis in various tumors. In the present study, we aimed to examine the role of NEAT1 in altering the properties of gliomas.Methods: Quantitative real-time PCR technology ...
Li Y +5 more
europepmc +4 more sources
lncRNA Kcnq1ot1 promotes bone formation by inhibiting miR-98-5p/Tbx5 axis in MC3T3-E1 cells. [PDF]
Exp Ther Med, 2022 Long non-coding (lnc)RNA KCNQ1 opposite strand/antisense transcript 1 (Kcnq1ot1) has been shown to regulate multiple biological processes. However, the functional role of Kcnq1ot1 in osteoporosis and the underlying mechanism are still unclear. The present study aimed to investigate the function of lncRNA Kcnq1ot1 in osteogenic differentiation. Alkaline
Wang F, Zhang F, Zheng F.
europepmc +4 more sources
Extracellular vesicle-derived miR-760 as a novel promising candidate biomarker differentiating stable RRMS from SPMS [PDF]
Scientific ReportsMultiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system with heterogenous clinical course, lacking non-invasive biomarkers for phenotype differentiation.
Karina Wasilewska +12 more
doaj +2 more sources
miR-98-5p as a novel biomarker suppress liver fibrosis by targeting TGFβ receptor 1 [PDF]
Hepatology International, 2022 Hepatic fibrosis is the repair reaction of excessive deposition and abnormal distribution of extracellular matrix after various liver injuries, especially chronic HBV infection, which is a key step in the development of various chronic liver diseases to cirrhosis.
Yanhua Ma +8 more
openaire +2 more sources
CS nerve growth factor regulates sevoflurane anesthesiainduced nerve injury in nerve cells [PDF]
, 2021 Purpose: Sevoflurane is the most commonly used anesthetic agent for surgery. However, it is associated with deficiency in learning and memory abilities. The study was aimed at investigating the role of nerve growth factor (NGF) in sevoflurane anesthesia ...
Dong, Lan +4 more
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Epigenetic alterations in hippocampus of SAMP8 senescent mice and modulation by voluntary physical exercise [PDF]
, 2014 The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's disease. With the purpose of identifying potential epigenetic markers involved in aging and neurodegeneration, here we analyzed the expression of 84 ...
Alvarez López, María J. +8 more
core +5 more sources
miR-98 Regulates TMPRSS2 Expression in Human Endothelial Cells: Key Implications for COVID-19 [PDF]
, 2020 The two main co-factors needed by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to enter human cells are angiotensin-converting enzyme 2 (ACE2) and transmembrane protease serine 2 (TMPRSS2).
Alessandro Matarese +3 more
core +1 more source