miR-98-5p plays a critical role in depression and antidepressant effect of ketamine [PDF]
Translational Psychiatry, 2021 Ketamine has been demonstrated to be a rapid-onset and long-lasting antidepressant, but its underlying molecular mechanisms remain unclear. Recent studies have emerged microRNAs as important modulators for depression treatment.
Chaoli Huang +10 more
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Effects of lncRNA HOXA11-AS on Sevoflurane-Induced Neuronal Apoptosis and Inflammatory Responses by Regulating miR-98-5p/EphA4 [PDF]
Mediators of Inflammation, 2023 Objective. To explore the molecular mechanism of sevoflurane-induced neurotoxicity and to determine whether lncRNA HOXA11-AS affects sevoflurane-induced neuronal apoptosis and inflammation by regulating miR-98-5p/EphA4. Methods.
Li Zhao +8 more
doaj +4 more sources
Hsa_circ_0003489 Drives PTX Resistance of Human NSCLC Cells Through Modulating miR-98-5p/IGF2 [PDF]
Pharmacogenomics and Personalized Medicine, 2023 Shaofeng Xia,1 Chenliang Wang2 1Department of Thoracic Surgery, The First People’s Hospital of Jiujiang City, Jiujiang, Jiangxi, People’s Republic of China; 2Department of Pathology, The First People’s Hospital of Jiujiang City, Jiujiang, Jiangxi, People’
Xia S, Wang C
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miR-98-5p Prevents Hippocampal Neurons from Oxidative Stress and Apoptosis by Targeting STAT3 in Epilepsy in vitro [PDF]
Neuropsychiatric Disease and Treatment, 2023 Zhizhuan Guo,1,2 Wenwen Zhong,3 Zhengshou Zou4 1Department of Neurology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, People’s Republic of China ...
Guo Z, Zhong W, Zou Z
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Astragaloside IV Inhibits Galactose-Deficient IgA1 Secretion via miR-98-5p in Pediatric IgA Nephropathy [PDF]
Frontiers in Pharmacology, 2021 Purpose: The factor associated with IgA nephropathy (IgAN) is an abnormality of IgA known as galactose-deficient IgA1 (Gd-IgA1). The purpose of this study was to determine the molecular role played by miRNAs in the formation of Gd-IgA1 in IgAN and ...
Caiqiong Liu +14 more
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MiR-98-5p plays suppressive effects on IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting CASP3 [PDF]
Journal of Orthopaedic Surgery and ResearchBackground This study aims to explore how miR-98-5p affects osteoarthritis, focusing on its role in chondrocyte inflammation, apoptosis, and extracellular matrix (ECM) degradation.
Hang Lv +4 more
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lncRNA Xist regulates sevoflurane-induced social and emotional impairment by modulating miR-98-5p/EDEM1 signaling axis in neonatal mice [PDF]
Molecular Therapy: Nucleic Acids, 2021 Long non-coding RNA (lncRNA) X-inactive specific transcript (Xist) is involved in apoptosis and inflammatory injury. This study aimed to assess the role of lncRNA Xist in sevoflurane-induced social and emotional impairment and neuronal apoptosis in ...
Lili Xu +7 more
doaj +2 more sources
A long non-coding RNA with important roles in the carcinogenesis [PDF]
Frontiers in Cell and Developmental Biology, 2022 Long non-coding RNAs are demonstrated to contribute to carcinogenesis. TMPO Antisense RNA 1 (TMPO-AS1) is an example of lncRNAs with crucial roles in this process. This lncRNA serves as a sponge for miR-320a, miR-383-5p, miR-329-3p, miR-126, miR-329, miR‐
Soudeh Ghafouri-Fard +6 more
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Long noncoding RNA ANRIL up‐regulates CCND1 via sponging miR‐98‐5p to promote TGF‐β1‐induced human airway smooth muscle cell proliferation, migration, and extracellular matrix deposition [PDF]
Kaohsiung Journal of Medical Sciences, 2022 Excessive proliferation and migration of airway smooth muscle cell (ASMC) contribute to asthma pathogenesis. Long noncoding RNAs (lncRNAs) are reported to take part in asthma pathogenesis.
Zhao‐Gang Zhong +5 more
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Circulating miR-146a-5p and miR-98–5p as Indicators of Inflammatory Response and Joint Pain in Chikungunya Fever [PDF]
Virus ResearchObjectives: Chikungunya virus (CHIKV) infection often results in chronic manifestations such as joint pain and fatigue. Recent evidence suggests that host microRNAs (miRNAs) may modulate antiviral and inflammatory responses during infection.
Delong Xie +7 more
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