Results 61 to 70 of about 31,458 (257)
Long non-coding RNA-NEAT1, a sponge for miR-98-5p, promotes expression of oncogene HMGA2 in prostate cancer. [PDF]
Biosci Rep, 2019 Abstract Increasing evidence demonstrated that noncoding RNAs (lncRNA, miRNA) play important roles in the cancer development. LncRNA NEAT1 functions as an oncogene in many cancers. However, the roles of NEAT1 in prostate cancer (PCa) remain largely unknown.
Guo Z, He C, Yang F, Qin L, Lu X, Wu J.
europepmc +3 more sources
Food Chemistry Advances, 2023 Isovitexin is a highly bioactive food-derived flavonoid currently attracting attention for its signal transduction-based antioxidant effects. This study focused on the potential molecular mechanisms by which isovitexin protects HaCaT cells from oxidation-
Xuechun Lv +8 more
doaj +1 more source
Journal of Orthopaedic Surgery and Research, 2023 Background Postmenopausal osteoporosis (PMOP) is a common condition that leads to a loss of bone density and an increased risk of fractures in women.
Zhibang Sun +10 more
doaj +1 more source
CircRNA-Associated CeRNAs Regulatory Axes in Retinoblastoma: A Systematic Scoping Review [PDF]
, 2022 Retinoblastoma (RB) is one of the most common childhood cancers caused by RB gene mutations (tumor suppressor gene in various patients). A better understanding of molecular pathways and the development of new diagnostic approaches may lead to better ...
Asadi, Mohammad Reza +8 more
core +1 more source
A Plasma Biomarker Panel of Four MicroRNAs for the Diagnosis of Prostate Cancer [PDF]
, 2018 © 2018 The Author(s). Prostate cancer is diagnosed in over 1 million men every year globally, yet current diagnostic modalities are inadequate for identification of significant cancer and more reliable early diagnostic biomarkers are necessary for ...
A. Collins +17 more
core +2 more sources
miR‑98‑5p promotes osteoblast differentiation in MC3T3‑E1 cells by targeting CKIP‑1
Molecular Medicine Reports, 2018 Casein kinase 2-interacting protein 1 (CKIP-1) is a negative regulator for bone formation. Previously, using bioinformatics analysis, CKIP‑1 has been predicted to serve the role of target gene of miR‑98‑5p. In the present study, the potential role of miR‑98‑5p in regulating osteoblast differentiation through CKIP‑1 was investigated.
Qiliang, Liu +4 more
openaire +3 more sources
BMC Neurology, 2023 Background Acute cerebral infarction (ACI) is a common cerebrovascular disease. Previous studies have shown that some abnormally expressed microRNAs (miRNAs) play important roles in ACI.
Wei Du, Lingyan Fan, Juan Du
doaj +1 more source
Profiling microRNA from Brain by Microarray in a Transgenic Mouse Model of Alzheimer’s Disease [PDF]
, 2017 MicroRNAs (miRNAs) are small noncoding RNAs, which regulate numerous cell functions by targeting mRNA for cleavage or translational repression, and have been found to play an important role in Alzheimer’s disease (AD).
Hai-lun Jiang +10 more
core +2 more sources
Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice [PDF]
, 2020 Cognitive and behavioural disturbances are a growing public healthcare issue for the modern society, as stressful lifestyle is becoming more and more common.
Griñán Ferré, Christian +3 more
core +1 more source
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
FEBS Open Bio, EarlyView.During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source