Results 91 to 100 of about 1,588,382 (270)

Organization of project activities in preschool educational institutions on the example of the Golden Pedagogical Ring project

Современное дошкольное образование
Background. Project activities in kindergarten are an urgent area that meets modern educational standards and contributes to the comprehensive development of children.
Larisa L. Shevchenko, Maria V. Stepanova
doaj   +1 more source

The hot core-ultracompact HII connection in G10.47+0.03 [PDF]

, 2004
We present infrared imaging and spectroscopic data of the complex massive star-forming region G10.47+0.03. The detection of seven mid-infrared (MIR) sources in our field combined with a sensitive Ks/ISAAC image allows to establish a very accurate ...
B. Brandl, B. Stecklum, Caswell, Cesaroni, Churchwell, Churchwell, Churchwell, Cohen, D. Apai, De Buizer, De Buizer, de Vicente, Draine, Garay, Grevesse, Hatchell, Hatchell, Hayward, Henning, Hofner, Hofner, I. Pascucci, Kaufman, Lada, Martins, Martín-Hernández, Maxia, Mokiem, Okamoto, Okamoto, Olmi, Olmi, Olmi, Osorio, Ossenkopf, Panagia, Panagia, Pantin, Persson, Saraph, Schaerer, Siebenmorgen, Stasinska, Stecklum, Th. Henning, Vacca, Walsh, Watt, Watt, Weingartner, Wood, Wyrowski, Yorke   +52 more
core   +3 more sources

Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring [PDF]

, 2009
Background miRNAs play important roles in the regulation of gene functions. Maternal dietary modifications during pregnancy and gestation have long-term effects on the offspring, but it is not known whether a maternal high fat (HF) diet during ...
Bruce, Kimberley D., Byrne, Christopher D., Cagampang, Felino R., Ceriello, Antonio, Didelot, Xavier, Hanson, Mark A., Lehnert, Hendrik, Vatish, Manu, Zhang, F. (Fang), Zhang, Junlong   +9 more
core   +3 more sources

The miR-200 Family Inhibits Epithelial-Mesenchymal Transition and Cancer Cell Migration by Direct Targeting of E-cadherin Transcriptional Repressors ZEB1 and ZEB2*

Journal of Biological Chemistry, 2008
MicroRNAs are small non-coding RNA molecules that can regulate gene expression by interacting with multiple mRNAs and inducing either translation suppression or degradation of mRNA.
M. Korpal, Esther S. Lee, G. Hu, Yibin Kang   +3 more
semanticscholar   +1 more source

Let it glow: genetically encoded fluorescent reporters in Plasmodium

Malaria Journal
The use of fluorescent proteins (FPs) in Plasmodium parasites has been key to understand the biology of this obligate intracellular protozoon. FPs like the green fluorescent protein (GFP) enabled to explore protein localization, promoter activity as well
Pia J. Thiele, Raquel Mela-Lopez, Stéphanie A. Blandin, Dennis Klug   +3 more
doaj   +1 more source

Klasik ve Modern Dönemde Yazılmış İki Usûlün (Mir'âtü'l-Uṣûl ile Uṣûlü’l-Fıkh) Mukayesesi

Tokat İlmiyat Dergisi, 2021
Fıkhın kaynaklarını ve temellerini, bunlardan hüküm çıkarma yöntemlerini konu alan fıkıh usulü ilmi ilk defa Müslümanlar tarafından oluşturulmuş ve geliştirilmiş özgün bir ilim dalıdır. Bu ilme dair günümüze kadar pek çok eser kaleme alınmıştır.
Hilal Özay, Hatice Esra Can
doaj   +1 more source

NRF2-driven miR-125B1 and miR-29B1 transcriptional regulation controls a novel anti-apoptotic miRNA regulatory network for AML survival [PDF]

, 2014
Transcription factor NRF2 is an important regulator of oxidative stress. It is involved in cancer progression, and has abnormal constitutive expression in acute myeloid leukaemia (AML).
A Ooi, AG Ooi, BN Chorley, BT Kvinlaug, C Luna, CR Zhao, D J MacEwan, E Estey, E Surdziel, F Kong, G Tan, GM DeNicola, H Wang, H Zhang, I Spinello, J Alam, J Gong, J Winter, JE Anderson, JJ Tsai, JJ Zhao, JN Gong, K M Bowles, K Okamoto, L Zaitseva, L Zaitseva, M Bousquet, M Bousquet, MB Sporn, MY Murray, N Hanada, N M Shah, P Moi, PA Konstantinopoulos, R Garzon, R Garzon, R Garzon, R Venugopal, S A Rushworth, S Liu, SA Rushworth, SA Rushworth, SA Rushworth, TWP Devling, W Blum, Y Wang, YR Kim   +46 more
core   +1 more source

Vascular miR‐181b controls tissue factor‐dependent thrombogenicity and inflammation in type 2 diabetes [PDF]

, 2020
BACKGROUND: Diabetes mellitus is characterized by chronic vascular inflammation leading to pathological expression of the thrombogenic full length (fl) tissue factor (TF) and its isoform alternatively-spliced (as) TF. Blood-borne TF promotes factor (
Chakraborty, Aritra, Dörner, Andrea, Friebel, Julian, Krueger, Andreas, Landmesser, Ulf, Rauch, Ursula, Ruf, Wolfram, Saffarzadeh, Mona, Stratmann, Bernd, Ta Bao, Loc, Tabaraie, Termeh, Tschoepe, Diethelm, Winter, Samantha J., Witkowski, Marco, Witkowski, Mario   +14 more
core   +1 more source

Therapeutic role of miR-19a/19b in cardiac regeneration and protection from myocardial infarction

Nature Communications, 2019
The primary cause of heart failure is the loss of cardiomyocytes in the diseased adult heart. Previously, we reported that the miR-17-92 cluster plays a key role in cardiomyocyte proliferation.
F. Gao, M. Kataoka, N. Liu, T. Liang, Zhan-Peng Huang, Fei Gu, Jian Ding, Jianming Liu, Feng Zhang, Qing Ma, Yingchao Wang, Mingming Zhang, Xiaoyun Hu, J. Kyselovič, Xinyang Hu, W. Pu, Jian’an Wang, Jinghai Chen, Da-Zhi Wang   +18 more
semanticscholar   +1 more source

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]

, 2017
Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma, A Nan, A Okuhara, A Turchinovich, B Aryal, B Mayr, B Sharif, B Zhang, BM Bolstad, BM Kuhn, BM Mayr, C Beyer, C Chen, C Guay, C Taurino, CL Andersen, D Dlouha, D Iliopoulos, D Zhang, DT Felson, F Kostopoulou, FE Nicolas, G Dennis Jr, G Li, G Tardif, GD Miles, GR Sondag, GS Lien, H Causton, JB van Meurs, JD Storey, JD Storey, KC Vickers, L Qi, M Cross, M Parrizas, MB Goldring, MC Hochberg, MD Paraskevopoulou, MP Gantier, OF Laterza, Q Zhuo, R Gernapudi, RF Loeser, RI Gregory, S Kluzek, S Kumar, S Miyaki, T Thomou, TA Karlsen, VM Borgonio Cuadra, W Cleveland, WM Reichmann, X Chen, X Chen, X Tan, X Wang, Y Klipper-Aurbach, Y Zhang, YH Li   +59 more
core   +2 more sources