Results 71 to 80 of about 1,588,382 (270)

Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression

open access: yesNature Communications, 2019
N6-methyladenosine (m6A) modification is an important mechanism in miRNA processing and maturation, but the role of its aberrant regulation in human diseases remained unclear. Here, we demonstrate that oncogenic primary microRNA-25 (miR-25) in pancreatic
Jialiang Zhang   +27 more
semanticscholar   +1 more source

Predicting the risk of malignisation of endometrial hyperplasia in reproductive age

open access: yesФундаментальная и клиническая медицина, 2020
Aim. Atypical endometrial hyperplasia (AEH) is a strong predictor of endometrial cancer, which is responsible for 80% of endometrial malignancies; out of all patients AEH, 10-50% are further diagnosed with endometrial cancer.
I. M. Ordiyants   +3 more
doaj   +1 more source

The ٍeffect of Eight Weeks of Moderate and High Intensity Resistance Training on micro-RNAs Associated with Reverse Cholesterol Transport in Older Wistar rats [PDF]

open access: yesفیزیولوژی ورزش و فعالیت بدنی, 2019
Purpose: Aging is associated with systemic dysfunctions in lipid metabolism and chronic inflammatory state which contribute to atherosclerotic. The purpose of this study was to investigate the effect of moderate and high intensity resistance training on ...
mehdi taheri gandomany   +3 more
doaj   +1 more source

The \u3cem\u3emir-51\u3c/em\u3e Family of MicroRNAs Functions in Diverse Regulatory Pathways in \u3cem\u3eCaenorhbditis elegans\u3c/em\u3e [PDF]

open access: yes, 2012
The mir-51 family of microRNAs (miRNAs) in C. elegans are part of the deeply conserved miR-99/100 family. While loss of all six family members (mir-51-56) in C. elegans results in embryonic lethality, loss of individual mir-51 family members results in a
Abbott, Allison L.   +2 more
core   +1 more source

MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis [PDF]

open access: yes, 2016
MicroRNA-155 (miR-155) is an important regulator of B cells in mice. B cells have a critical role in the pathogenesis of rheumatoid arthritis (RA). Here we show that miR-155 is highly expressed in peripheral blood B cells from RA patients compared with ...
Alivernini, Stefano   +13 more
core   +2 more sources

Conditional neuronal deletion of microRNA‐141/200c cluster, but not microRNA‐181a/b‐1 cluster, is protective against experimental stroke in male mice

open access: yesPhysiological Reports, Volume 13, Issue 15, August 2025.
Abstract MicroRNAs (miRs) regulate the translation of target genes often in a cell‐type specific manner. We previously demonstrated that downregulation of either miR‐181a or miR‐200c with intracranial injection of an inhibitor is protective against experimental stroke in mice.
Lijun Xu   +9 more
wiley   +1 more source

Ovarian cancer cell-secreted exosomal miR-205 promotes metastasis by inducing angiogenesis

open access: yesTheranostics, 2019
Background: By providing oxygen, nutrients and metastatic conduits, tumour angiogenesis is essential for cancer metastasis. Cancer cell-secreted microRNAs can be packaged into exosomes and are implicated in different aspects of tumour angiogenesis ...
Liuqing He   +6 more
semanticscholar   +1 more source

Weltraumstation MIR

open access: yes, 2022
Mir (russ. für: Frieden, Welt), von der Sowjetunion erbaute, bemannte Raumstation, die von 1986 bis 2001 die Erde ...
Straub, Wolfgang   +2 more
openaire   +2 more sources

FAIM Is Regulated by MiR-206, MiR-1-3p and MiR-133b [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2020
Apoptosis plays an important role during development, control of tissue homeostasis and in pathological contexts. Apoptosis is executed mainly through the intrinsic pathway or the death receptor pathway, i.e., extrinsic pathway. These processes are tightly controlled by positive and negative regulators that dictate pro- or anti-apoptotic death receptor
Elena Coccia   +13 more
openaire   +4 more sources

Mechanisms of action of extracellular miRNAs

open access: yesZdorovʹe Rebenka, 2022
The mechanisms of action of extracellular miRNAs are given in the scientific review. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library databases.
A.E. Abaturov, V.L. Babуch
doaj   +1 more source

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