Results 81 to 90 of about 1,588,382 (270)

MicroRNA-210 Suppresses Junction Proteins and Disrupts Blood-Brain Barrier Integrity in Neonatal Rat Hypoxic-Ischemic Brain Injury. [PDF]

, 2017
Cerebral edema, primarily caused by disruption of the blood-brain barrier (BBB), is one of the serious complications associated with brain injury in neonatal hypoxic-ischemic encephalopathy (HIE).
Dasgupta, Chiranjib, Huang, Lei, Li, Yong, Ma, Qingyi, Zhang, Lubo   +4 more
core   +2 more sources

Neutrophil microRNAs

Biological Reviews, Volume 99, Issue 3, Page 864-877, June 2024.
ABSTRACT Neutrophils are considered ‘first‐line defence’ cells as they can be rapidly recruited to the site of the immune response. As key components of non‐specific immune mechanisms, neutrophils use phagocytosis, degranulation, and formation of neutrophil extracellular traps (NETs) to fight pathogens.
Marzena Garley, Karolina Nowak, Ewa Jabłońska   +2 more
wiley   +1 more source

Lack of association between miR-27a, miR-146a, miR-196a-2, miR-492 and miR-608 gene polymorphisms and colorectal cancer [PDF]

Scientific Reports, 2014
Colorectal cancer (CRC) is one of the most common cancers worldwide with high mortality rates. MicroRNAs (miRNAs) have an established role in the development of different cancers. Single nucleotide polymorphisms (SNPs) in miRNA related genes were linked with various gastrointestinal malignancies.
Juozas Kupcinskas, Indre Bruzaite, Simonas Juzenas, Ugne Gyvyte, Laimas Jonaitis, Gediminas Kiudelis, Jurgita Skieceviciene, Marcis Leja, Henrikas Pauzas, Algimantas Tamelis, Dainius Pavalkis, Limas Kupcinskas   +11 more
openaire   +2 more sources

Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway [PDF]

, 2015
Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens.
Drakaki, A, Georgoulias, V, Hatziapostolou, M, Iliopoulos, D, Polytarchou, C, Poultsides, GA, Souglakos, J, Vorvis, C   +7 more
core   +2 more sources

Tapping the Full Potential of Infrared Spectroscopy for the Analysis of Technical Lignins

ChemSusChem, Volume 17, Issue 10, May 21, 2024.
From days to minutes: genuine high‐throughput & in‐depth analysis of technical lignins via fast and facile IR spectroscopy aided by chemometrics. Abstract We present an approach to overcome the challenges associated with the increasing demand of high‐throughput characterization of technical lignins, a key resource in emerging bioeconomies. Our approach
Ivan Sumerskii, Stefan Böhmdorfer, Otgontuul Tsetsgee, Irina Sulaeva, Hajar Khaliliyan, Oliver Musl, Katharina Dorninger, Alexander Tischer, Karin Potthast, Thomas Rosenau, Richard G. Brereton, Antje Potthast   +11 more
wiley   +1 more source

Shear stress regulation of miR-93 and miR-484 maturation through nucleolin. [PDF]

, 2019
Pulsatile shear (PS) and oscillatory shear (OS) elicit distinct mechanotransduction signals that maintain endothelial homeostasis or induce endothelial dysfunction, respectively.
Chen, Lili, Chen, Shanshan, Chien, Shu, Gongol, Brendan, Han, Yue, He, Ming, Huang, Po-Hsun, Johnson, David A, Kang, Jian, Li, Jie, Li, Yi-Shuan, Liu, Jun-Hui, Lytle, Christian, Marin, Traci, Martin, Marcy, Shyy, John Y-J, Sun, Wei, Wang, Shen-Chih, Zhang, Jiao   +18 more
core  

Discovery of planetary nebulae using predictive mid-infrared diagnostics

, 2012
We demonstrate a newly developed mid-infrared planetary nebula (PN) selection technique. It is designed to enable efficient searches for obscured, previously unknown, PN candidates present in the photometric source catalogues of Galactic plane MIR sky ...
Bojicic, Ivan, Cohen, Martin, Frew, David J., Green, Anne J., Guzman-Ramirez, Lizette, Parker, Quentin A., Sabin, Laurence, Stupar, Milorad, Vogt, Frederic   +8 more
core   +1 more source

miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development [PDF]

, 2015
MicroRNAs play a crucial role in the regulation of cell growth and differentiation. Mice with genetic deletion of miR-375 exhibit impaired glycemic control due to decreased β-cell and increased α-cell mass and function.
Herrmanns, K, Latreille, M, Malecki, MT, McCarthy, MI, Owen, KR, Renwick, N, Rülicke, T, Stoffel, M, Tuschl, T   +8 more
core   +2 more sources

Automized inline monitoring in perfused mammalian cell culture by MIR spectroscopy without calibration model building

Engineering in Life Sciences, Volume 24, Issue 3, March 2024.
Abstract Process Analytical Technologies (PATs) are taking a key role in the run for automatization in the biopharmaceutical industry. Spectroscopic methods such as Raman spectroscopy or mid‐infrared (MIR) spectroscopy are getting more recognition in the recent years for inline monitoring of bioprocesses due to their ability to measure various ...
Hannah Marienberg, Nicole Desch, Vitalii Mozin, Lorenz Sykora‐Mirle, Anja Müller, Andreas Roth, Mathias Käfer, Rüdiger Neef   +7 more
wiley   +1 more source

MiR-CLIP reveals iso-miR selective regulation in the miR-124 targetome [PDF]

Nucleic Acids Research, 2020
Abstract Many microRNAs regulate gene expression via atypical mechanisms, which are difficult to discern using native cross-linking methods. To ascertain the scope of non-canonical miRNA targeting, methods are needed that identify all targets of a given miRNA.
Wang, Yuluan, Soneson, Charlotte, Malinowska, Anna L, Laski, Artur, Ghosh, Souvik, Kanitz, Alexander, Gebert, Luca F R, Robinson, Mark D, Hall, Jonathan   +8 more
openaire   +6 more sources