Effects of electroacupuncture on behavioral deficits, hippocampal neuronal death and oxidative stress in rats with parkinson"s disease [PDF]
We aimed to study electroacupuncture (EA) for its potential neuroprotection against oxidative stress, death of hippocampal neurons and behavioral deficits in rats with Parkinson"s disease (PD). PD was induced by rotenone (2 mg/kg, subcutaneous injection)
Dingding LIU, Yan YUE
doaj +1 more source
Regulation of microRNA with food. Part 1. Food of plant origin
Тhe scientific review presents the mechanisms of microRNA regulation of biological processes in the human body with the help of food products of plant origin.
A.E. Abaturov, V.L. Babуch
doaj +1 more source
Non-coding RNAs (ncRNAs) have been shown to regulate gene expression involved in tumor progression of multiple malignancies. Our previous studies indicated that large tumor suppressor kinase 1 (LATS1), a core part of Hippo signaling pathway, functions as
Jing Zhang +7 more
semanticscholar +1 more source
AbstractWe previously demonstrated that acidic bile activates NF‐κB, deregulating the expression of oncogenic miRNA markers, in pre‐malignant murine laryngopharyngeal mucosa. Here, we hypothesize that the in vitro exposure of human hypopharyngeal cells to acidic bile deregulates cancer‐related miRNA markers that can be reversed by BAY 11‐7082, a ...
Sotirios G. Doukas +2 more
openaire +2 more sources
The role of miRNAs in the development of cholangiopathies. Part 1
The role of miRNA in the development of cholangiopathies is given in the scientific review. This article discusses the role of miRNA in primary sclerosing cholangitis and primary biliary cholangitis.
A.E. Abaturov, V.L. Babуch
doaj +1 more source
microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma. [PDF]
Glycolysis was reported to have a positive correlation with radioresistance. Our previous study found that the miR-33a functioned as a tumor suppressor in malignant melanoma by targeting hypoxia-inducible factor1-alpha (HIF-1α), a gene known to promote ...
Cao, Ke +12 more
core +1 more source
Diagnostic Potential of miR-126, miR-143, miR-145, and miR-652 in Malignant Pleural Mesothelioma [PDF]
Malignant pleural mesothelioma (MPM) is difficult to distinguish from reactive mesothelial proliferations (RMPs). It is uncertain whether miRNAs are useful biomarkers for differentiating MPM from RMPs. Thus, we screened with a quantitative RT-PCR (RT-qPCR)-based platform the expression of 742 miRNAs in formalin-fixed, paraffin-embedded, preoperative ...
Andersen, Morten +5 more
openaire +3 more sources
Introduction Efficiently meeting recruitment targets is foundational to clinical trial success. Past reviews on improving recruitment efficiency have highlighted only a few evidence-supported strategies; some of which may be context-specific, infeasible,
Natasha Hudek +9 more
doaj +1 more source
Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 [PDF]
Sphingosine kinase 1 (SphK1) upregulation is associated with pathologic pulmonary vascular remodeling in pulmonary arterial hypertension (PAH), but the mechanisms controlling its expression are undefined.
Chen, Jiwang +6 more
core +1 more source
The nanoparticle‐on‐slit (NPoS) cavity has emerged as a sub‐wavelength platform for efficient coherent frequency conversion between mid‐infrared and visible light, and for nanoscale nonlinear vibrational spectroscopy. This numerical study identifies the NPoS quasi‐normal modes, relates them to known nanogap patterns, and predicts the relative ...
Huatian Hu +3 more
wiley +1 more source

