Results 41 to 50 of about 1,588,382 (270)

Cancer-derived exosomal miR-25-3p promotes pre-metastatic niche formation by inducing vascular permeability and angiogenesis

Nature Communications, 2018
Cancer-derived exosomes are considered a major driver of cancer-induced pre-metastatic niche formation at foreign sites, but the mechanisms remain unclear.
Zhicheng Zeng, Yuling Li, Yangjian Pan, X. Lan, F. Song, Jingbo Sun, K. Zhou, Xiaolong Liu, X. Ren, Feifei Wang, Jinlong Hu, Xiaohui Zhu, Wei Yang, W. Liao, Guoxin Li, Yanqing Ding, L. Liang   +16 more
semanticscholar   +1 more source

miR‐9, miR‐21, miR‐27b, and miR‐34a Expression in HPV16/58/52‐Infected Cervical Cancer [PDF]

BioMed Research International, 2020
The aim of this study was to observe the expression of miR‐9, miR‐21, miR‐27b, and miR‐34a related with E6/E7 in HPV16‐, HPV52‐, and HPV58‐infected cervical cancer patients and explore their possible role in cervical cancer with HPV infection. The expression levels of 4 miRNAs were detected in cervical exfoliated cells using qRT‐PCR.
Mi Liu, Wei Wang, Haixing Chen, Yi Lu, Daisha Yuan, Yongjiu Deng, Danlu Ran   +6 more
openaire   +2 more sources

RETRACTED ARTICLE: CircHIPK3 promotes colorectal cancer growth and metastasis by sponging miR-7

Cell Death and Disease, 2018
Mounting evidences indicate that circular RNAs (circRNAs) have a vital role in human diseases, especially cancers. More recently, circHIPK3, a particularly abundant circRNA, was proposed to be involved in tumorigenesis.
K. Zeng, Xiaoxiang Chen, Mu Xu, Xiangxiang Liu, Xiuxiu Hu, Tao Xu, Huiling Sun, Yu-qin Pan, Bangshun He, Shukui Wang   +9 more
semanticscholar   +1 more source

MicroRNAs miR-19, miR-340, miR-374 and miR-542 regulate MID1 protein expression

PLOS ONE, 2018
The MID1 ubiquitin ligase activates mTOR signaling and regulates mRNA translation. Misregulation of MID1 expression is associated with various diseases including midline malformation syndromes, cancer and neurodegenerative diseases. While this indicates that MID1 expression must be tightly regulated to prevent disease states specific mechanisms ...
Kristoffer Unterbruner, Frank Matthes, Judith Schilling, Rohit Nalavade, Stephanie Weber, Jennifer Winter, Sybille Krauß   +6 more
openaire   +5 more sources

Circulating microRNAs, miR-939, miR-595, miR-519d and miR-494, Identify Cirrhotic Patients with HCC [PDF]

PLOS ONE, 2015
The performance of circulating biomarkers for the diagnosis of hepatocellular carcinoma (HCC) is sub-optimal. In this study we tested circulating microRNAs as biomarkers for HCC in cirrhotic patients by performing a two stage study: a discovery phase conducted by microarray and a validation phase performed by qRT-PCR in an independent series of 118 ...
FORNARI, FRANCESCA, FERRACIN, MANUELA, TRERE', DAVIDE, MILAZZO, MADDALENA, MARINELLI, SARA, GALASSI, MARZIA, VENERANDI, LAURA, POLLUTRI, DANIELA, PATRIZI, CLARISSA, BORGHI, ALBERTO, Foschi, Francesco G., STEFANINI, GIUSEPPE FRANCESCO, Negrini, Massimo, BOLONDI, LUIGI, GRAMANTIERI, LAURA   +14 more
openaire   +5 more sources

Mejorando la IOT con el Dispositivo Airtraq®. Descripción de la maniobra "KET"

Revista Electrónica de AnestesiaR, 2011
La vía aérea difícil (VAD) es la primera causa de morbi-mortalidad anestésica. Representa el 50% de las complicaciones severas no fatales y el 30% de las muertes de causa anestésica. Uno de cada tres casos de VAD son imprevistos.
José Viñuales Cabeza, M Fernández Rodrigo, J Garafulla García, J Buil Lanaspa, L Colomina Callen   +4 more
doaj   +1 more source

Zemstvo Tradition as a Particularly Valuable Intangible Cultural Heritage of the Russian North

Арктика и Север, 2023
The article presents the scientific results obtained during the study of the zemstvo self-government tradition in the Russian North. This tradition is considered as a particularly valuable intangible cultural heritage.
Nikolay N. Terebikhin
doaj   +1 more source

Elevating microRNA-122 in blood improves outcomes after temporary middle cerebral artery occlusion in rats. [PDF]

, 2016
Because our recent studies have demonstrated that miR-122 decreased in whole blood of patients and in whole blood of rats following ischemic stroke, we tested whether elevating blood miR-122 would improve stroke outcomes in rats.
Ander, Bradley P, Cox, Christopher, Dykstra-Aiello, Cheryl, Hull, Heather, Jickling, Glen C, Liu, Da Zhi, Sharp, Frank R, Shroff, Natasha, Stamova, Boryana, Zhan, Xinhua   +9 more
core   +2 more sources

Hypoxic Tumor-Derived Exosomal miR-301a Mediates M2 Macrophage Polarization via PTEN/PI3Kγ to Promote Pancreatic Cancer Metastasis.

Cancer Research, 2018
Exosomes are emerging as important mediators of the cross-talk between tumor cells and the microenvironment. However, the mechanisms by which exosomes modulate tumor development under hypoxia in pancreatic cancer remain largely unknown.
Xiaofeng Wang, Guangtao Luo, Kun-dong Zhang, Jun Cao, Chen Huang, T. Jiang, Bing-ya Liu, Liping Su, Z. Qiu   +8 more
semanticscholar   +1 more source

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients [PDF]

Journal of Translational Medicine, 2013
Abstract Background Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor with poor clinical outcome. Identification and development of new markers could be beneficial for the diagnosis and prognosis of GBM patients. Deregulation of microRNAs (miRNAs or miRs) is involved in GBM.
Qiu, Shuwei, Lin, Sheng, Hu, Dan, Feng, Yimin, Tan, Yang, Peng, Ying   +5 more
openaire   +4 more sources