Results 41 to 50 of about 317,294 (179)

MicroRNA‐661 modulates redox and metabolic homeostasis in colon cancer

Molecular Oncology, Volume 11, Issue 12, Page 1768-1787, December 2017., 2017
miR661 modulates redox homeostasis and metabolism in colon cancer. More specifically, miR661 decreases the pentose phosphate pathway and carbohydrate metabolism, which leads to a diminished tolerance to metabolic stress. This phenotype seems to be partially associated to a reduction of H6PD and PKM2.
Marta Gómez de Cedrón, Rebeca Acín Pérez, Ruth Sánchez‐Martínez, Susana Molina, Jesús Herranz, Jaime Feliu, Guillermo Reglero, Jose Antonio Enríquez, Ana Ramírez de Molina   +8 more
wiley   +1 more source

Multiversion Document Warehouse: An Approach to Multidimensional Analysis

Journal of Intelligence Studies in Business, 2012
Document warehouses allow the storage of selected and filtered heterogeneous documents, as well as their exploitation through multidimensional analyses techniques. However, the content of documents is dynamic and changes over time.
Kaïs Khrouf, Jamel Feki, Chantal Soulé-Dupuy   +2 more
doaj   +1 more source

Diagnostic Potential of miR-126, miR-143, miR-145, and miR-652 in Malignant Pleural Mesothelioma [PDF]

The Journal of Molecular Diagnostics, 2014
Malignant pleural mesothelioma (MPM) is difficult to distinguish from reactive mesothelial proliferations (RMPs). It is uncertain whether miRNAs are useful biomarkers for differentiating MPM from RMPs. Thus, we screened with a quantitative RT-PCR (RT-qPCR)-based platform the expression of 742 miRNAs in formalin-fixed, paraffin-embedded, preoperative ...
Andersen, Morten, Grauslund, Morten, Ravn, Jesper, Sørensen, Jens B, Andersen, Claus B, Santoni-Rugiu, Eric   +5 more
openaire   +3 more sources

Serum miR‐224, miR‐760, miR‐483‐5p, miR‐378 and miR‐375 as potential novel biomarkers in rheumatoid arthritis

International Journal of Clinical Practice, 2021
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease which affects various tissues and organs mainly joints. Serum microRNAs are considered a new class of non-coding RNA which plays a vital role in pathogenesis of RA.The current study was conducted on 80 RA patients and 80 healthy participants.
Omayma O. Abdelaleem, Nermeen A. Fouad, Olfat G. Shaker, Tarek I. Ahmed, Noha K. Abdelghaffar, Hanaa M. Eid, Abdelrahmaan A. Mohamed, Ahmed Magdy Elebiary, Mohamed M. Mohamed, Rania H. Mahmoud   +9 more
openaire   +2 more sources

Neutrophil microRNAs

Biological Reviews, Volume 99, Issue 3, Page 864-877, June 2024.
ABSTRACT Neutrophils are considered ‘first‐line defence’ cells as they can be rapidly recruited to the site of the immune response. As key components of non‐specific immune mechanisms, neutrophils use phagocytosis, degranulation, and formation of neutrophil extracellular traps (NETs) to fight pathogens.
Marzena Garley, Karolina Nowak, Ewa Jabłońska   +2 more
wiley   +1 more source

Organization of project activities in preschool educational institutions on the example of the Golden Pedagogical Ring project

Современное дошкольное образование
Background. Project activities in kindergarten are an urgent area that meets modern educational standards and contributes to the comprehensive development of children.
Larisa L. Shevchenko, Maria V. Stepanova
doaj   +1 more source

Tapping the Full Potential of Infrared Spectroscopy for the Analysis of Technical Lignins

ChemSusChem, Volume 17, Issue 10, May 21, 2024.
From days to minutes: genuine high‐throughput & in‐depth analysis of technical lignins via fast and facile IR spectroscopy aided by chemometrics. Abstract We present an approach to overcome the challenges associated with the increasing demand of high‐throughput characterization of technical lignins, a key resource in emerging bioeconomies. Our approach
Ivan Sumerskii, Stefan Böhmdorfer, Otgontuul Tsetsgee, Irina Sulaeva, Hajar Khaliliyan, Oliver Musl, Katharina Dorninger, Alexander Tischer, Karin Potthast, Thomas Rosenau, Richard G. Brereton, Antje Potthast   +11 more
wiley   +1 more source

Automized inline monitoring in perfused mammalian cell culture by MIR spectroscopy without calibration model building

Engineering in Life Sciences, Volume 24, Issue 3, March 2024.
Abstract Process Analytical Technologies (PATs) are taking a key role in the run for automatization in the biopharmaceutical industry. Spectroscopic methods such as Raman spectroscopy or mid‐infrared (MIR) spectroscopy are getting more recognition in the recent years for inline monitoring of bioprocesses due to their ability to measure various ...
Hannah Marienberg, Nicole Desch, Vitalii Mozin, Lorenz Sykora‐Mirle, Anja Müller, Andreas Roth, Mathias Käfer, Rüdiger Neef   +7 more
wiley   +1 more source

The clinical significance of circulating miR-21, miR-142, miR-143, and miR-146a in patients with prostate cancer

Journal of Medical Biochemistry, 2022
Background: Prostate cancer (PCa) is the most common type of solid tissue cancer among men in western countries. In this study, we determined the levels of circulating miR-21, miR-142, miR-143, miR-146a, and RNU 44 levels as controls for early diagnosis of PCa.
Bolayırlı Ibrahim Murat, Önal Bülent, Adıgüzel Mutlu, Konukoğlu Dildar, Demirdağ Çetin, Kurtuluş Eda Merve, Türegün Fethi Ahmet, Uzun Hafize   +7 more
openaire   +5 more sources

Microvesicle-associated and circulating microRNAs in diabetic dyslipidemia: miR-218, miR-132, miR-143, and miR-21, miR-122, miR-155 have biomarker potential

Cardiovascular Diabetology, 2023
Abstract Background Circulating MicroRNAs (miRNAs) carried by microvesicles (MVs) have various physiological and pathological functions by post-transcriptional regulation of gene expression being considered markers for many diseases including diabetes and dyslipidemia.
Miruna Nemecz, Diana Simona Stefan, Ioana Karla Comarița, Alina Constantin, Gabriela Tanko, Cristian Guja, Adriana Georgescu   +6 more
openaire   +3 more sources