Results 31 to 40 of about 480,809 (228)
miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. [PDF]
, 2012 Acquired resistance to classical chemotherapeutics is a major obstacle in cancer treatment. Doxorubicin is frequently used in breast cancer therapy either as single-agent or in combination with other drugs like docetaxel and cyclophosphamide.
Oak, Prajakta S. +11 more
core +1 more source
The role of miRNAs in the development of cholangiopathies. Part 2
Zdorovʹe Rebenka, 2023 The role of miRNA in the development of cholangiopathies is considered in the scientific review. This article discusses the role of miRNA in biliary atresia, polycystic liver disease, and cholangiocarcinoma.
A.E. Abaturov, V.L. Babуch
doaj +2 more sources
Mejorando la IOT con el Dispositivo Airtraq®. Descripción de la maniobra "KET"
Revista Electrónica de AnestesiaR, 2011 La vía aérea difícil (VAD) es la primera causa de morbi-mortalidad anestésica. Representa el 50% de las complicaciones severas no fatales y el 30% de las muertes de causa anestésica. Uno de cada tres casos de VAD son imprevistos.
José Viñuales Cabeza +4 more
doaj +1 more source
Change impact analysis for software product lines
Journal of King Saud University: Computer and Information Sciences, 2016 A software product line (SPL) represents a family of products in a given application domain. Each SPL is constructed to provide for the derivation of new products by covering a wide range of features in its domain.
Jihen Maâzoun +2 more
doaj +1 more source
MicroRNA‐661 modulates redox and metabolic homeostasis in colon cancer
Molecular Oncology, Volume 11, Issue 12, Page 1768-1787, December 2017., 2017 miR661 modulates redox homeostasis and metabolism in colon cancer. More specifically, miR661 decreases the pentose phosphate pathway and carbohydrate metabolism, which leads to a diminished tolerance to metabolic stress. This phenotype seems to be partially associated to a reduction of H6PD and PKM2.
Marta Gómez de Cedrón +8 more
wiley +1 more source
Zdorovʹe Rebenka, 2022 The scientific review considers the mechanisms of action of cytoplasmic microRNAs, namely miRNA-mediated silencing, which is caused during the initiation and post-initiation period of translation.
A.E. Abaturov, V.L. Babуch
doaj +1 more source
BMP signaling in vascular diseases
FEBS Letters, Volume 586, Issue 14, Page 1993-2002, July 04, 2012., 2012 Bone morphogenetic proteins (BMPs) are members of the transforming growth factor‐β (TGF‐β) family that signal via type I and type II serine/threonine kinase receptors and intracellular Smad transcription factors. BMPs are multifunctional regulators of development and tissue homeostasis and they were initially characterized as inducers of bone ...
Jie Cai +3 more
wiley +1 more source
Multiversion Document Warehouse: An Approach to Multidimensional Analysis
Journal of Intelligence Studies in Business, 2012 Document warehouses allow the storage of selected and filtered heterogeneous documents, as well as their exploitation through multidimensional analyses techniques. However, the content of documents is dynamic and changes over time.
Kaïs Khrouf +2 more
doaj +1 more source
Zdorovʹe Rebenka, 2022 The scientific review presents the mechanisms of action of cytoplasmic miRNAs, namely miRNA-mediated posttranslational silencing. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE ...
A.E. Abaturov, V.L. Babуch
doaj +1 more source
La artrodesis de las cuatro esquinas con placa circular
Revista Iberoamericana de Cirugía de la Mano, 2007 Objetivo: La artrodesis de las cuatro esquinas del carpo fue descrita inicialmente para el tratamiento del colapso avanzado del carpo e incluye la extirpación del escafoides y la fusión de los huesos semilunar, piramidal, hueso grande y ...
A. García López +4 more
doaj +1 more source