The role of miRNAs in the development of cholangiopathies. Part 2
The role of miRNA in the development of cholangiopathies is considered in the scientific review. This article discusses the role of miRNA in biliary atresia, polycystic liver disease, and cholangiocarcinoma.
A.E. Abaturov, V.L. Babуch
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Diagnostic and prognostic potential of serum miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429 in ovarian cancer patients [PDF]
Owing to late diagnosis in advanced disease stages, prognosis of patients with epithelial ovarian cancer (EOC) is poor. The quantification of deregulated levels of microRNAs could facilitate earlier diagnosis and improve prognosis of EOC.Seven microRNAs (miR-7, miR-16, miR-25, miR-93, miR-182, miR-376a and miR-429) were quantified in the serum of 180 ...
Xiaodan Meng +8 more
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miR‐17, miR‐19b, miR‐20a, and miR‐106a are down‐regulated in human aging [PDF]
SummaryAging is a multifactorial process where deterioration of body functions is driven by stochastic damage while counteracted by distinct genetically encoded repair systems. To better understand the genetic component of aging, many studies have addressed the gene and protein expression profiles of various aging model systems engaging different ...
Hackl, Matthias +27 more
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Genetic Variants miR-126, miR-146a, miR-196a2, and miR-499 in Polycystic Ovary Syndrome [PDF]
Introduction: Alterations in certain microRNAs (miRNAs) and their target genes have reported in polycystic ovary syndrome (PCOS) and other disease of the female reproductive system, and so may be potential biomarkers. We hypothesised alterations in the prevalence of four miRNAs single nucleotide polymorphism (SNP) variants miR-126 rs4636297, miR-146a ...
Li, R. +6 more
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The scientific review considers the mechanisms of action of cytoplasmic microRNAs, namely miRNA-mediated silencing, which is caused during the initiation and post-initiation period of translation.
A.E. Abaturov, V.L. Babуch
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Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients [PDF]
Abstract Background Glioblastoma multiforme (GBM) is the most common and aggressive brain tumor with poor clinical outcome. Identification and development of new markers could be beneficial for the diagnosis and prognosis of GBM patients. Deregulation of microRNAs (miRNAs or miRs) is involved in GBM.
Qiu, Shuwei +5 more
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The scientific review presents the mechanisms of action of cytoplasmic miRNAs, namely miRNA-mediated posttranslational silencing. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE ...
A.E. Abaturov, V.L. Babуch
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The effect of different intensities Resistance Training on expression mir-204 and transcription factors of osteogenic, Runx2 and biomechanical properties on bone in Old male Wistar rats [PDF]
Purpose: Bones are largely influenced by nutrition, activity levels and lifestyle, and structural adaptations in the form and size of the bone occur by the forces of weight bearing and forces applied by the muscles.
ZAHRA HEMATI FARSANI +3 more
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The scientific review presents the mechanisms of action of intranuclear miRNAs, namely microRNA-mediated regulation of the non-coding RNA (ncRNA) transcriptome and alternative splicing.
A.E. Abaturov, V.L. Babуch
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MiR-574-5P, miR-1827, And miR-4429 As Potential Biomarkers For Schizophrenia [PDF]
Abstract Schizophrenia is a severe chronic debilitating disorder with millions of affected individuals. Lack of a reliable mollecular diagnostic invokes the identification of novel biomarkers. To elucidate the molecular basis of the disease, two mRNA expression arrays including GSE93987 and GSE38485, and one miRNA array, GSE54914, were ...
Omran Davarinejad +7 more
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