Plasma microRNA levels following resection of metastatic melanoma [PDF]
Melanoma remains the leading cause of skin cancer–related deaths. Surgical resection and adjuvant therapies can result in disease-free intervals for stage III and stage IV disease; however, recurrence is common.
Abrams, Zachary B +10 more
core +3 more sources
microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma. [PDF]
Glycolysis was reported to have a positive correlation with radioresistance. Our previous study found that the miR-33a functioned as a tumor suppressor in malignant melanoma by targeting hypoxia-inducible factor1-alpha (HIF-1α), a gene known to promote ...
Cao, Ke +12 more
core +1 more source
MicroRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 locus, regulate proliferation, apoptosis, migration and invasion in metastatic prostate cancer cells [PDF]
miRNAs act as oncogenes or tumor suppressors in a wide variety of human cancers, including prostate cancer (PCa). We found a severe and consistent downregulation of miRNAs, miR-154, miR-299-5p, miR-376a, miR-376c, miR-377, miR-381, miR-487b, miR-485-3p, miR-495 and miR-654-3p, mapped to the 14q32.31 region in metastatic cell lines as compared with ...
Formosa, A +9 more
openaire +4 more sources
Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a. [PDF]
A comprehensive genomic and proteomic, computational, and physiological approach was employed to examine the (previously unexplored) role of microRNAs (miRNAs) as regulators of internal anal sphincter (IAS) smooth muscle contractile phenotype and basal ...
Addya, Sankar +6 more
core +3 more sources
El bloqueo del plexo cervical superficial ecoguiado es una técnica sencilla y que, complementada con una adecuada sedación, puede proporcionar las condiciones adecuadas para la realización de la exéresis de la glándula paratiroides sin necesidad de ...
Manuel Eced Sánchez +5 more
doaj +1 more source
Mačevi u plugove ili vice versa (Iz; Mih; Jl)
Aktualna situacija rata u Ukrajini poticaj je za promišljanje o smislu i besmislu rata. Utemeljujući svoje promišljanje na starozavjetnoj tradiciji, pretežito onoj proročkoj, autor donosi biblijsko-teološki uvid u koncept rata i mira.
Anđelo Maly
doaj +1 more source
Involvement of MicroRNA Families in Cancer [PDF]
Collecting representative sets of cancer microRNAs (miRs) from the literature we show that their corresponding families are enriched in sets of highly interacting miR families.
Arjona, Dolores +3 more
core +5 more sources
AbstractMicroRNAs are a class of non‐coding molecules found to regulate a variety of cellular functions in health and disease. Dysregulation of microRNAs is involved in liver disease, especially hepatocarcinogenesis. Since primary hepatic malignancies are typically characterized by late diagnosis, frequent recurrence, and poor response to adjuvant ...
Karakatsanis, A. +5 more
openaire +3 more sources
A heterozygous variant in the human cardiac miR-133 gene, MIR133A2, alters miRNA duplex processing and strand abundance [PDF]
BACKGROUND MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate gene expression. Sequential cleavage of miRNA precursors results in a ~22 nucleotide duplex of which one strand, the mature miRNA, is typically loaded into the ...
Anderson, Elizabeth +4 more
core +1 more source
Abstract Background Circulating MicroRNAs (miRNAs) carried by microvesicles (MVs) have various physiological and pathological functions by post-transcriptional regulation of gene expression being considered markers for many diseases including diabetes and dyslipidemia.
Miruna Nemecz +6 more
openaire +3 more sources

