Loss of DNA mismatch repair proteins in prostate cancer [PDF]
Medicine, 2020 Abstract Recent studies have suggested an increased risk of prostate cancer in men with Lynch syndrome driven by germline mutations in mismatch repair (MMR) genes. However, the incidence and clinical implication of MMR deficiency in sporadic prostate cancers remain poorly understood.
Meenal Sharma +2 more
openaire +3 more sources
A Novel Reverse Combination Configuration to Reduce Mismatch Loss for Stratospheric Airship Photovoltaic Arrays [PDF]
Applied SciencesEnhancing the output power of stratospheric airship photovoltaic arrays during months with weak irradiance is crucial for extending the endurance of airships.
Chuan Shan +5 more
doaj +2 more sources
Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair [PDF]
Nature Communications, 2018 Polymerase proofreading and the mismatch repair pathway maintain the fidelity of DNA replication. Here the authors show that tumors with concurrent loss of function of both pathways lead to mutation signatures that are not simply a sum of the signatures ...
N. J. Haradhvala +11 more
doaj +2 more sources
Metric learning loss functions to reduce domain mismatch in the x-vector space for language recognition [PDF]
, 2020 International audienceState-of-the-art language recognition systems are based on dis-criminative embeddings called x-vectors. Channel and gender distortions produce mismatch in such x-vector space where em-beddings corresponding to the same language are ...
Illina, Irina +2 more
core +4 more sources
Effect of Cell Electrical Mismatch on Output of Crystalline Photovoltaic Modules
Energies, 2022 The importance of energy supply and demand has been emphasized over the past few years. Renewable energy without regional bias continues to attract attention.
Somin Park +4 more
doaj +1 more source
File_S1.txt - "Examination of gene loss in the DNA mismatch repair pathway and its mutational consequences in a fungal phylum" [PDF]
, 2021 Matrix of MMR gene presence/absence in Ascomycota for "Examination of gene loss in the DNA mismatch repair pathway and its mutational consequences in a fungal phylum"
Xing-Xing Shen (823794) +3 more
core +1 more source
Examination of gene loss in the DNA mismatch repair pathway and its mutational consequences in a fungal phylum [PDF]
, 2021 Supplementary data for "Examination of gene loss in the DNA mismatch repair pathway and its mutational consequences in a fungal phylum"
Xing-Xing Shen (823794) +3 more
core +1 more source
In Lynch syndrome adenomas, loss of mismatch repair proteins is related to an enhanced lymphocytic response. [PDF]
, 2009 Contains fulltext : 80304.pdf (Publisher’s version ) (Open Access)AIMS: Lynch syndrome-associated tumours are characterized by the presence of an increased number of tumour-infiltrating lymphocytes.
Meijer, T.W. +4 more
core +1 more source
README.txt - "Examination of gene loss in the DNA mismatch repair pathway and its mutational consequences in a fungal phylum" [PDF]
, 2021 README file for "Examination of gene loss in the DNA mismatch repair pathway and its mutational consequences in a fungal phylum"
Xing-Xing Shen (823794) +3 more
core +1 more source
Prime editing efficiency and fidelity are enhanced in the absence of mismatch repair
Nature Communications, 2022 Prime Editing is a versatile genome engineering tool. Here, the authors identify the DNA repair pathway known as mismatch repair as inhibitory for Prime Editing, thus, loss of mismatch repair enhances the efficiency of Prime Editing.
J. Ferreira da Silva +7 more
doaj +1 more source