Results 251 to 260 of about 210,406 (304)

Mismatch Repair Deficiency Profiling and Its Impact on Management and Prognosis in Endometrial Cancer Patients: A Comprehensive Update. [PDF]

Cureus
Almperi EA, Margioula-Siarkou C, Almperis A, Margioula-Siarkou G, Flindris S, Daponte AI, Papamitsou T, Dinas K, Petousis S.   +8 more
europepmc   +1 more source

Mismatch repair deficiency drives malignant progression and alters the tumor immune microenvironment in glioblastoma models. [PDF]

J Clin Invest
Puigdelloses Vallcorba M, Soni N, Choi SW, Rawat K, Joshi T, Friedman S, Buonfiglioli A, Angione A, Chen Z, Piñero G, Price G, Dedhia M, Roche R, Radkevich E, Bowcock AM, Bhatt D, Edelmann W, Samstein RM, Richardson TE, Tsankova NM, Tsankov AM, Bindra RS, Rabadan R, Vasquez JC, Hambardzumyan D.   +24 more
europepmc   +1 more source

Mismatch Repair System Gene Expression in FFPE Samples from Breast Cancer Patients. [PDF]

Med Sci (Basel)
Quidute R, Quidute P, Perez MM, Peiró CHF, da Veiga GL, da Costa Aguiar Alves B, Fonseca FLA.   +6 more
europepmc   +1 more source

Microsatellite Instability Status and Mismatch Repair Defects Testing in Endometrial Cancer-Insights from the Multicenter E-PEC Trial. [PDF]

Diagnostics (Basel)
Eser B, Papior D, Salmanton-García J, Cornely OA, Morgenstern B, Herpel C, Radosa JC, Almuheimid A, Aktas B, Weydandt L, Wittenborn J, Meyer-Wilmes P, Friebe V, Leidinger C, Kimmig R, Thangarajah F.   +15 more
europepmc   +1 more source

Deciphering mismatch repair protein expression variability in gastric cancer: clinical and prognostic implications. [PDF]

BMC Cancer
Zhong F, Zhang M, Xu L, Cui J, Chen Z, Gao Q.   +5 more
europepmc   +1 more source

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Mismatch repair

Molecular Biology, 2006
Specific repair systems are activated in response to DNA lesions. Mismatch repair protects the genome of prokaryotic and eukaryotic cells from errors arising during replication or induced by mutagenic factors. The mismatch repair system distinguishes between the newly synthesized and pattern DNA strands by the extent of methylation and checks the ...
N. V. Golyasnaya, N. A. Tsvetkova
  +6 more sources

Eukaryotic DNA mismatch repair

Current Opinion in Genetics & Development, 1999
Eukaryotic mismatch repair (MMR) has been shown to require two different heterodimeric complexes of MutS-related proteins: MSH2-MSH3 and MSH2-MSH6. These two complexes have different mispair recognition properties and different abilities to support MMR. Alternative models have been proposed for how these MSH complexes function in MMR.
R D, Kolodner, G T, Marsischky
openaire   +2 more sources

Mismatch repair prefers exons

Nature Genetics, 2017
A new analysis of cancer genomes identifies a decrease in the mutation burden of exons, but not introns, as compared to expectation. This difference can be explained by preferential recruitment of the DNA mismatch repair machinery to a protein modification that marks exons.
Dashiell J, Massey, Amnon, Koren
openaire   +2 more sources