Results 271 to 280 of about 210,406 (304)
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Gan to kagaku ryoho. Cancer & chemotherapy, 1997
A DNA mismatch repair system exists that repairs mispaired bases formed during DNA replication and genetic recombination. Genetic defects in this mismatch repair system are known to increase the rate of spontaneous mutation in Escherichia coli. Some cases of inherited cancer are associated with inherited defects of mismatch repair genes, showing the ...
M, Ikejima, T, Shimada
openaire +1 more source
A DNA mismatch repair system exists that repairs mispaired bases formed during DNA replication and genetic recombination. Genetic defects in this mismatch repair system are known to increase the rate of spontaneous mutation in Escherichia coli. Some cases of inherited cancer are associated with inherited defects of mismatch repair genes, showing the ...
M, Ikejima, T, Shimada
openaire +1 more source
2016
The DNA replication machinery synthesizes ~500 DNA base pairs every second in bacteria and ~50 base pairs every second in eukaryotes [1]. Mismatches can occur in a newly synthesized DNA due to misincorporation of nucleotides by DNA polymerase or slippage during DNA replication.
openaire +1 more source
The DNA replication machinery synthesizes ~500 DNA base pairs every second in bacteria and ~50 base pairs every second in eukaryotes [1]. Mismatches can occur in a newly synthesized DNA due to misincorporation of nucleotides by DNA polymerase or slippage during DNA replication.
openaire +1 more source
PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
New England Journal of Medicine, 2015Bjarne R Bartlett +2 more
exaly +2 more sources
Recent progress in Lynch syndrome and other familial colorectal cancer syndromes
Ca-A Cancer Journal for Clinicians, 2018Patrick M Boland +2 more
exaly
Mismatch repair deficient colorectal cancer in the era of personalized treatment
Nature Reviews Clinical Oncology, 2010David Cunningham
exaly
DNA mismatch repair and adjuvant chemotherapy in sporadic colon cancer
Nature Reviews Clinical Oncology, 2010Frank A Sinicrope
exaly

