Results 101 to 110 of about 3,426,573 (245)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Report to the President for year ended June 30, 2006, Lemelson–MIT Program

open access: yes, 2006
This report contains the following sections: Annual Invention Awards; Lemelson–MIT InvenTeams; Lemelson–MIT Invention Index; Lemelson–MIT Support for MIT Programs and ...
Finn, Kristin
core  

International diffusion of energy technology : report of a workshop held on June 2-3, 1976, at Dedham, Massachusetts [PDF]

open access: yes, 1976
Prepared in association with Center for International Studies, Massachusetts Institute of TechnologyGrant #E(49-18)-2295, Task Order No.2, from the Energy Research and Development ...
MIT Energy Lab
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Modeling of electric power demand growth [PDF]

open access: yes, 1973
Paper given at MIT conference entitled Energy: Demand, Conservation and Institutional Problems, February 12-15 ...
Schweppe, Fred C.   +2 more
core  

Fractional Model Reference Adaptive PIλDμ Control

open access: yesJournal of New Results in Science, 2016
This study explains the auto-adjustable fractional order the proportional–integral–derivative (PID) controller design methodology by using the technique of fractional model reference adaptive control (fractional MRAC).
Hüseyin Arpacı   +2 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Managerial switching and myopia [PDF]

open access: yes, 1987
Pew Charitable Trust, the Center for Energy Policy Research at MIT and the National Science ...
Tirole, Jean, Laffont, Jean-Jacques
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Rule of Law, Democracy, Openness, and Income: Estimating the Interrelationships [PDF]

open access: yes
We estimate the interrelationships among economic institutions, political institutions, openness, and income levels, using identification through heteroskedasticity (IH).
Roberto Rigobon, Dani Rodrik
core  

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