Results 111 to 120 of about 3,426,573 (245)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Dynamic Modeling of Electromechanical Energy Conversion Systems in Advanced Gas Turbines using Adaptive Control Algorithms

open access: yesJournal of Engineering
This paper introduces a rigorous dynamic modeling and control platform of the electromechanical energy conversion systems of single-shaft, heavy-duty gas turbines.
Ahmed Imad Kamin
doaj   +1 more source

Effect Of Adaptation Gain On System Performance For Model Reference Adaptive Control Scheme Using Mit Rule

open access: yes, 2010
{"references": ["Karl J. Astrom, Bjorn Wittenmark, \"Adaptive control\" , 2nd ed.\nPearson Education Asia, 2001, pp185-225.", "Rey-Chue Hwang, Huang-Chu Huang, Wei-Shen Chi, \"A New\nFuzzy PID-Like Controller\", IEEE international conference on\nsystems, man, cybernetics, vol. 5, 2000.", "K. S.
Swarnkar, Pankaj   +2 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Deep learning-based early prediction of life-threatening ventricular arrhythmias using long-term Holter ECG signals

open access: yesFrontiers in Cardiovascular Medicine
IntroductionVentricular arrhythmias (VAs) are among the primary reasons for sudden cardiac death, and their early detection requires a key factor to reduce patient mortality. Conventional tools used to identify arrhythmias (manual and rule-based) are not
Yifan Wu   +8 more
doaj   +1 more source

Analisis Model Reference Adaptive Control (MRAC) dengan MIT Rule pada Suhu Mesin Sealer

open access: yesJurnal Elektronika dan Otomasi Industri
Mesin sealer merupakan alat yang penting dalam industri untuk mengirimkan plastik dan mengemas bahan, dengan aplikasi di industri makanan, minuman, farmasi, dan manufaktur. Proses pendaftaran ini penting untuk menjaga kesegaran produk, meningkatkan keamanan, dan estetika kemasan. Tantangan yang dihadapi dalam penggunaan mesin sealer meliputi pengaturan
Sri Aji Eka Mahendra Sri Aji Eka Mahendra   +2 more
openaire   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Report to the President for year ended June 30, 2005, Lemelson–MIT Program

open access: yes, 2005
This report contains the following sections: Annual Invention Awards; Lemelson–MIT InvenTeams; Lemelson–MIT Invention Index; Other Public Outreach and Education; Lemelson–MIT Support for MIT Programs and ...
Finn, Kristin
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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