Results 131 to 140 of about 3,426,573 (245)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Report to the President for year ended June 30, 2010, Lemelson–MIT Program
, 2010 This report contains the following sections: Annual Innovation Awards; 2010 Lemelson–MIT Prize; 2010 Lemelson–MIT Award for Sustainability; 2010 Lemelson–MIT Student Prize; 2010 Lemelson–MIT Collegiate Student Prizes; Invention Education; Lemelson–MIT ...
Schuler, Joshua
core
HDACiDB: a database for histone deacetylase inhibitors
Drug Design, Development and Therapy, 2015 Kasi Murugan,1 Shanmugasamy Sangeetha,2 Shanmugasamy Ranjitha,2 Antony Vimala,2 Saleh Al-Sohaibani,1 Gopal Rameshkumar21Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia; 2Bioinformatics Laboratory ...
Murugan K +5 more
doaj
PharmaceuticalsArtificial intelligence (AI) is emerging as a valuable complementary tool in small-molecule drug discovery, augmenting traditional methodologies rather than replacing them.
Sarfaraz K. Niazi
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Report to the President for year ended June 30, 2009, Lemelson–MIT Program
, 2009 This report includes the following sections: Annual Invention Awards; 2009 Lemelson–MIT Award for Sustainability; 2009 Lemelson–MIT Student Prize; 2009 Lemelson–MIT Collegiate Student Prizes; Invention Education; Lemelson–MIT Support for MIT Programs and
Schuler, Joshua
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Development and testing of three dimensional, two-fluid code THERMIT for LWR core and subchannel applications [PDF]
, 1979 At head of title: Energy Laboratory and Dept. of Nuclear Engineering.Sponsored by Boston Edison Company and others under MIT Energy Laboratory Electric Utility ...
Kazimi, Mujid S., Kelly, John Edward
core
Zeitschrift Korpora Deutsch als FremdspracheDieser Beitrag untersucht die Verwendung und Akzeptanz von V2- und V3-Strukturen in deutschen Deklarativsätzen anhand Korpusdaten von Personen mit Deutsch als Erst- (L1) und Zweitsprache (L2).
doaj +2 more sources
Die "Canadian Head Rule" für Patienten mit leichtem Schädelhirntrauma
, 2004 Hintergrund: Sensitivität, Spezifität und Anwendbarkeit der Canadian Head Rule (CHR) wurde für Münsteraner Patienten evaluiert. Methoden: Eingeschlossen wurden 122 SHT-Patienten (m=74; w=48; 40.0 +/- 19.0J) der Jahre 1999-2000. Die Indikation zur CCT wurde entsprechend der CHR ermittelt und mit den CCT-Resultaten verglichen. Ergebnisse: 4/122 Patienten
openaire