Results 141 to 150 of about 921,496 (243)

RNF13 regulates the endolysosomal pathway through interaction with the small GTPase Arl8B

open access: yesThe FEBS Journal, EarlyView.
The E3 ubiquitin ligase RNF13 functions as a regulatory scaffold, organizing Arl8B‐dependent complexes and tuning downstream signaling that controls endolysosomal organization and trafficking. In this model, wild‐type RNF13 associates with Arl8B on endolysosomes, whereas Arl8B (E22D/F55A) or RNF13 (L244A) variants weaken complex assembly, potentially ...
Audrey M. Sénécal   +4 more
wiley   +1 more source

A mitochondrial-based prognostic score for risk stratification in acute myeloid leukemia. [PDF]

open access: yesBlood Res
Santos IC   +10 more
europepmc   +1 more source

Energetic dysregulations in psychotic disorders: Targets for new therapeutics

open access: yesThe FEBS Journal, EarlyView.
The present review synthesizes literature documenting aberrant energy production and use, specifically related to mitochondrial and redox dysregulation, in psychotic disorders. Findings from different levels of investigation—genetic, cellular, and in vivo imaging—converge on aberrant energy metabolism as a hallmark of psychotic disorders.
Jacey Anderson   +10 more
wiley   +1 more source

Lo scandalo del mito

open access: yes, 2007
Il processo di demitizzazione avviato dal razionalismo settecentesco è posto in relazione con la problematica del rapporto tra filosofia, mito poetico e mito verosimile, formulata da Platone, ed è riconsiderato alla luce della revisione del ruolo del ...
BOVA, Anna Clara
core  

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney   +4 more
wiley   +1 more source

Echoes in the powerhouse: mito-lncRNAs contribution to cardiac function and disease. [PDF]

open access: yesActa Pharmacol Sin
Chaurembo AI   +12 more
europepmc   +1 more source

Tetraploid Wheat Germplasm Diversity Scan based on the Durum Wheat Genome Assembly

open access: yes, 2018
The genome of modern durum wheat (DW) cultivar Svevo has been assembled based on a combination of whole genome shotgun sequencing (270X), NRGene deNovoMagic assembler, high-resolution genetic mapping obtained from the cross between Svevo DW and Zavitan ...
Raj K Pasam   +18 more
core  

Mitochondrial control of ciliary gene expression and structure in striatal neurons

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen   +5 more
wiley   +1 more source

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