ADSC-derived mitochondrial nanovesicles transplantation alleviates capsular fibrosis and inflammation and improves joint mobility in a rat model of adhesive capsulitis. [PDF]
Zhu Y +11 more
europepmc +1 more source
Libretti di sala - MITO SettembreMusica (2007-2025)
Questa sezione raccoglie, in ordine cronologico, tutti i libretti di sala del festival MITO SettembreMusica dal 2007 ad oggi. Si tratta di piccoli volumi distribuiti in sala durante gli spettacoli previsti dal programma generale del festival.
MITO SettembreMusica Archivio Storico
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Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang +11 more
wiley +1 more source
Analysis of the ERG25 gene family based on the whole-genome sequence in Trametes versicolor and its response to light stress. [PDF]
Cheng X +5 more
europepmc +1 more source
Unraveling a Diagnostic Enigma: A TECPR2 Case Solved Through Multi‐Omic Genomics
ABSTRACT TECPR2 is a key regulator of autophagy, encoded by the TECPR2 gene. Pathogenic variants in this gene have been linked to a rare hereditary sensory and autonomic neuropathy with intellectual disability (HSAN9). We report a teenage female with a syndromic intellectual disability disorder associated with neuromuscular abnormalities.
Teresa Zhao +123 more
wiley +1 more source
Rebalancing mitochondrial dynamics restores succinate dehydrogenase activity and reduces succinate release in hepatocellular carcinoma. [PDF]
Wu JY +6 more
europepmc +1 more source
Report on the human genome initiative. Draft
United States. Department of Energy. Office of Energy Research. Health and Environmental Research Advisory Committee. Subcommittee on Human Genome
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GLP‐1R agonist semaglutide protects human forebrain organoids from cholesterol‐induced neurotoxicity
Abstract INTRODUCTION Dysregulated cholesterol metabolism represents a critical metabolic stressor in the central nervous system, contributing to neuronal injury across multiple neurological conditions, including Alzheimer's disease (AD). While glucagon‐like peptide‐1 receptor (GLP‐1R) agonists show neuroprotective potential, their capacity to directly
Feifei Yu +10 more
wiley +1 more source
Whole‐brain input–output mapping reveals that DMDLepRb and DMHLepRb neurons share a highly conserved global connectivity architecture yet exhibit local connection biases: DMDLepRb neurons preferentially integrate arousal and defensive signals, whereas DMHLepRb neurons favor viscerosensory and metabolic inputs, uncovering a principle of conserved global
Yaxin Hao +8 more
wiley +1 more source
Iron and Other Metal Ions in Human Health and Disease
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley +1 more source

