Results 241 to 250 of about 616,240 (353)

MAVS oligomerization drives a faster and more efficient antiviral signaling activation at peroxisomes compared to mitochondria

open access: yesThe FEBS Journal, EarlyView.
Cells rely on mitochondria and peroxisomes to trigger antiviral defenses via the protein MAVS. This manuscript demonstrates that the robust production of antiviral effectors resulting from MAVS activation at peroxisomes is faster than at mitochondria due to a swifter oligomerization of this protein at peroxisomal membranes. These results underscore the
Bruno Ramos   +4 more
wiley   +1 more source

Coenzyme A mitigates cystine‐deprivation‐induced ferroptosis by suppressing the iron‐starvation response

open access: yesThe FEBS Journal, EarlyView.
Cystine (Cys2) deprivation in pancreatic cancer cells induces oxidative stress that destabilizes cytosolic iron–sulfur cluster (ISC) proteins, triggering an iron‐regulatory protein (IRP)‐mediated iron‐starvation response (ISR). This leads to increased iron uptake (via TFRC), an expanded labile iron pool, and ferroptosis.
Mingjun Tan   +8 more
wiley   +1 more source

Natural Variation of a PPR Coding Gene SST1 Confers Salt Tolerance During Soybean Domestication

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Soil salinity is one of the constraints that adversely affect seedling growth and limit soybean yield. Identifying salt tolerance genes and profiling their allele variants are crucial for elucidating the mechanisms underlying salt tolerance in soybean and enabling the genetic improvement of salt‐tolerant cultivars.
Hui Wang   +14 more
wiley   +1 more source

Tracheobronchial mucoid pseudotumor

open access: yesOpen Medicine, 2012
Itoi Satoshi   +5 more
doaj   +1 more source

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