Results 61 to 70 of about 616,240 (353)

Mito y clasificación social [PDF]

, 2017
Al igual que las sociedades de las que forman parte, los mitos también están estratificados. La mitocrítica debe tener en cuenta la clasificación social del contexto socio-histórico donde nace cada mito.
Losada Goya, José Manuel
core   +1 more source

Functional and Biogenetical Heterogeneity of the Inner Membrane of Rat-Liver Mitochondria [PDF]

, 1971
Rat liver mitochondria were fragmented by a combined technique of swelling, shrinking, and sonication. Fragments of inner membrane were separated by density gradient centrifugation.
Allmann D. W., Ashwell M., Beattie D. S., Beattie D. S., Brunner G., Burstone M. S., Davis K. A., Delbruck A., Fiske C. H., Folch J., Gear A. R. L., Gear A. R. L., Gear A. R. L., Gelder B. F., Gotterer G. S., Hasegawa E., Hawley E. S., Johnson A. B., Klingenberg M., Kuntzel H., Labbe R. F., Lentz P. E., Neupert W., Neupert W., Novikoff A. B., Ohnishi K., Omura T., Parsons D. F., Parsons D. F., Pette D., Pollak J. K., Pullmann M. E., Raw J., Raw J., Reith A., Schneider W. C., Schuel H., Schumacher H.-H., Sebald W., Sebald W., Seligman A. M., Sies H., Sottocasa G. L., Stoffel W., Strecker H. J., Swick R. W., Szarkowska L., Tabor C. W., Tol A., Vazquez J. J., Yonetani T.   +50 more
core   +1 more source

Alkyltriphenylphosphonium Binding to Cardiolipin Triggers Oncosis in Cancer Cells

Advanced Science, EarlyView.
Alkyltriphenylphosphonium, exemplified by TPP+‐C14, preferentially accumulates in mitochondria and selectively binds to cardiolipin, a key phospholipid of the inner mitochondrial membrane, causing loss of mitochondrial membrane potential, severe cellular ATP depletion, and calcium imbalance.
Jin Li, Hang Zheng, Yuxing Lin, Ziwei Zhao, Yijia Mai, Zhangrong Lou, Qiang Liu, Zhao Ma, Chengjun Wu   +8 more
wiley   +1 more source

Leigh syndrome global patient registry: uniting patients and researchers worldwide

Orphanet Journal of Rare Diseases, 2023
Background Leigh Syndrome (LS) is a rare genetic neurometabolic disorder, that leads to the degeneration of the central nervous system and subsequently, early death. LS can be caused by over 80 mutations in mitochondrial or nuclear DNA.
Sophia Zilber, Kasey Woleben, Simon C. Johnson, Carolina Fischinger Moura de Souza, Danielle Boyce, Kevin Freiert, Courtney Boggs, Souad Messahel, Melinda J. Burnworth, Titilola M. Afolabi, Saima Kayani   +10 more
doaj   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

The Antimicrobial Effect of Silver Ion Impregnation into Endodontic Sealer against Streptococcus mutans. [PDF]

, 2008
Pulpal and periradicular diseases are primarily caused by bacterial invasion of the root canal system as a result of caries progression. The presence of residual bacteria at the time of root canal completion (obturation) is associated with significantly ...
Chugal, N, Hsiao, G, Kang, MK, Kim, D, Kreth, J, Mito, R, Nguyen, M, Shi, W   +7 more
core   +3 more sources

TP019/#1387  Rosella (GOG-3073, ENGOT-OV72/MITO): a phase 3 study of relacorilant + nab paclitaxel vs. nab-paclitaxel in platinum-resistant ovarian cancer [PDF]

, 2023
Domenica Lorusso, Andrea Bagaméri, Erin Bishop, Anita Chudecka-Głaz, Alix Devaux, Laurence Gladieff, Mary E. Gordinier, Jae‐Weon Kim, Jacob Korach, Michael McCollum, Linda Mileshkin, Bradley J. Monk, Shibani Nicum, Angélica Nogueira‐Rodrigues, Ana Oaknin, David M. O’Malley, Mauro Orlando, Lyndah Dreiling, Iulia Cristina Tudor, Alexander Olawaiye   +19 more
openalex   +1 more source

Investigating Mitochondrial Viscosity in Ferroptosis‐Mediated Drug‐Induced Liver Injury using a Double‐Targeted Strategy

Advanced Science, EarlyView.
Utilizing a mitochondrial double‐targeted strategy, a novel near‐infrared fluorescent probe (FTZ‐2) is established for monitoring viscosity variations in ferroptosis‐mediated drug‐induced liver injury. In summary, this work provided a practical strategy for the early diagnosis and evaluation of liver injury.
Yongqing Zhou, Yan Wang, Bing Huang, Hosoowi Lee, Mei Yan, Juyoung Yoon   +5 more
wiley   +1 more source

Meningeal carcinomatosis presenting with leukoencephalopathy-like imaging findings

eNeurologicalSci, 2019
Meningeal carcinomatosis is a unique and rare form of metastasis observed in patients with malignant tumours. Diagnosis is simple when the primary lesion of the malignant tumour is clear, and when multiple miliary lesions are confirmed via cranial ...
Hiroshi Tsuji, Shioya Ayako, Norio Takayashiki, Toshiyuki Irie, Satoshi Itoi, Taisuke Kodama, Yuki Kaji, Ryota Matsuoka, Ryota Mashiko, Yasushi Shibata, Akiko Ishii, Yuko Siato, Akira Tamaoka   +12 more
doaj   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source