Results 1 to 10 of about 690,904 (305)

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

open access: yesNature, 2018
Both mitochondria and lysosomes are essential for maintaining cellular homeostasis, and dysfunction of both organelles has been observed in multiple diseases.
Yvette C Wong   +2 more
exaly   +2 more sources

Green Extraction of Phenolic Compounds from Lotus (Nelumbo nucifera Gaertn) Leaf Using Deep Eutectic Solvents: Process Optimization and Antioxidant Activity

open access: yesSeparations, 2023
Natural deep eutectic solvents (NDESs) were used to extract flavonoids and polyphenols from lotus (Nelumbo nucifera Gaertn.) leaves at the same time, and the extraction process was optimized to provide reference for the effective development and ...
Jiwei Yang   +10 more
doaj   +1 more source

Calcium Binding Mechanism of Soybean Peptide with Histidine Alteration by Molecular Docking Analysis and Spectroscopic Methods

open access: yesFoods, 2022
Histidine (His) carries a unique heteroaromatic imidazole side chain and plays an irreplaceable role in peptides and proteins. With the current study, we aimed to determine the characteristics and functional activities of the bone density of soy peptide ...
Jing Gan   +8 more
doaj   +1 more source

Mitochondria metabolism sets the species-specific tempo of neuronal development

open access: yesScience, 2023
Neuronal development in the human cerebral cortex is considerably prolonged compared with that of other mammals. We explored whether mitochondria influence the species-specific timing of cortical neuron maturation.
Ryohei Iwata   +26 more
semanticscholar   +1 more source

The Protective Effects of Water-Soluble Alginic Acid on the N-Terminal of Thymopentin

open access: yesMolecules, 2023
Thymopentin (TP5) has exhibited strong antitumor and immunomodulatory effects in vivo. However, the polypeptide is rapidly degraded by protease and aminopeptidase within a minute at the N-terminal of TP5, resulting in severe limitations for further ...
Haiyu Ji   +7 more
doaj   +1 more source

Effect of fermentation using different lactic acid bacteria strains on the nutrient components and mineral bioavailability of soybean yogurt alternative

open access: yesFrontiers in Nutrition, 2023
IntroductionAnalysis of the composition of yogurt alternatives (YAs) during fermentation provides critical information for evaluating its quality and nutritional attributes.MethodWe investigated the effects of homotypic (HO) and heterotypic (HE) lactic ...
Jing Gan   +11 more
doaj   +1 more source

Expression of Synj2bp in mouse liver regulates the extent of wrappER-mitochondria contact to maintain hepatic lipid homeostasis

open access: yesBiology Direct, 2022
Background In mouse liver hepatocytes, nearly half of the surface area of every mitochondrion is covered by wrappER, a wrapping-type of ER that is rich in fatty acids and synthesizes lipoproteins (VLDL) (Anastasia et al.
Nicolò Ilacqua   +9 more
doaj   +1 more source

The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics

open access: yesBiomedicines, 2022
Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 base pair double-stranded circular DNA that encodes for 13 vital proteins
Sanjana Saravanan   +5 more
doaj   +1 more source

Protective Effects of Hippophae rhamnoides L. Phenylpropanoids on Doxorubicin-Induced Cardiotoxicity in Zebrafish

open access: yesMolecules, 2022
Hippophae rhamnoides L. is a deciduous shrub that contains many unique bioactive substances. This sea buckthorn possesses anticancer, antioxidant, anti-inflammatory, and cardiovascular protective properties.
Gang Li   +7 more
doaj   +1 more source

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