Results 21 to 30 of about 589,060 (317)

An Epigenetic Role of Mitochondria in Cancer

, 2022
Mitochondria are not only the main energy supplier but are also the cell metabolic center regulating multiple key metaborates that play pivotal roles in epigenetics regulation.
Sun, Yihong, Yihong Sun, Yufeng Shi, Jin Zhang, Zhang, Jin, Xinye Wang, Juxiang Chen, Chen, Juxiang, Shi, Yufeng, Wang, Xinye, Chen, Chao, Chao Chen, Yu’e Liu, Liu, Yu’e   +13 more
core   +1 more source

CaMKII induces permeability transition through Drp1 phosphorylation during chronic β-AR stimulation

Nature Communications, 2016
β-adrenergic receptor signaling induces mitochondrial permeability transition pore (mPTP) opening. Here, Xuet al. show that this effect is mediated by phosphorylation of mitochondrial fission protein Drp1 by CamKII, which increases the frequency of ...
Shangcheng Xu, Pei Wang, Huiliang Zhang, Guohua Gong, Nicolas Gutierrez Cortes, Weizhong Zhu, Yisang Yoon, Rong Tian, Wang Wang   +8 more
doaj   +1 more source

Glucose promotes cell growth by suppressing branched-chain amino acid degradation

Nature Communications, 2018
Hypertrophic cardiomyocytes switch their metabolism from fatty acid oxidation to glucose use, but the functional role of this change is unclear. Here the authors show that high intracellular glucose inhibits the degradation of branched-chain amino acids,
Dan Shao, Outi Villet, Zhen Zhang, Sung Won Choi, Jie Yan, Julia Ritterhoff, Haiwei Gu, Danijel Djukovic, Danos Christodoulou, Stephen C. Kolwicz, Daniel Raftery, Rong Tian   +11 more
doaj   +1 more source

A crucial role of the mitochondrial protein import receptor MOM19 for the biogenesis of mitochondria [PDF]

, 1994
The novel genetic method of "sheltered RIP" (repeat induced point mutation) was used to generate a Neurospora crassa mutant in which MOM19, a component of the protein import machinery of the mitochondrial outer membrane, can be depleted.
W Neupert, Lill, Roland, Harkness, Troy A.A.,, van der Klei, Ida, Neupert, Walter, Harkness, Troy A. A., Klei, Ida J. van der, TA Harkness, Klei, Ida van der,, Nargang, Frank E.,, I van der Klei, Neupert, Walter,, Lill, Roland,, van der Klei, Ida ; id_orcid, Nargang, Frank E., FE Nargang, R Lill   +16 more
core   +1 more source

Mitochondria and Cytoprotection

Biochemistry Research International, 2012
no ...
Brenner, Catherine, Ventura-Clapier, Renée, Jacotot, Etienne   +2 more
openaire   +5 more sources

Calcium and mitochondria [PDF]

FEBS Letters, 2004
The literature suggests that the physiological functions for which mitochondria sequester Ca2+ are (1) to stimulate and control the rate of oxidative phosphorylation, (2) to induce the mitochondrial permeability transition (MPT) and perhaps apoptotic cell death, and (3) to modify the shape of cytosolic Ca2+ pulses or transients.
Gunter, Thomas E., Yule, David I., Gunter, Karlene K., Eliseev, Roman A., Salter, Jason D.   +4 more
openaire   +2 more sources

Resolution of Inflammation after Skeletal Muscle Ischemia–Reperfusion Injury: A Focus on the Lipid Mediators Lipoxins, Resolvins, Protectins and Maresins

Antioxidants, 2022
Skeletal muscle ischemia reperfusion is very frequent in humans and results not only in muscle destruction but also in multi-organ failure and death via systemic effects related to inflammation and oxidative stress.
Cindy Barnig, Gaetan Lutzweiler, Margherita Giannini, Anne Lejay, Anne-Laure Charles, Alain Meyer, Bernard Geny   +6 more
doaj   +1 more source

Sarcopenia and cardiovascular diseases: A systematic review and meta‐analysis

Journal of Cachexia, Sarcopenia and Muscle, 2023
Sarcopenia is an age‐related disease and is often accompanied by other diseases. Now, many studies have shown that cardiovascular diseases (CVDs) may raise the incidence rate of sarcopenia. Therefore, the purpose of this study was to conduct a systematic
Xinrong Zuo, Xuehong Li, Kuo Tang, Rui Zhao, Minming Wu, Yang Wang, Tao Li   +6 more
doaj   +1 more source

A new limit for blood metabolite analysis using 1H NMR spectroscopy

Journal of Magnetic Resonance Open, 2022
Human blood is the most widely used biospecimen in the clinic and the metabolomics field. While both mass spectrometry and NMR spectroscopy are the two premier analytical platforms in the metabolomics field, NMR exhibits several unsurpassed ...
G.A. Nagana Gowda, Vadim Pascua, Daniel Raftery   +2 more
doaj   +1 more source

Mitochondria in Health and Diseases

, 2020
Mitochondria are subcellular organelles evolved by endosymbiosis of bacteria with eukaryotic cells characteristics. They are the main source of ATP in the cell and play a pivotal role in cell life and cell death.
Andrey V. Kozlov, Amadou K. S. Camara, Sabzali Javadov   +2 more
core   +1 more source